Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Aboriginal Peoples' Health / Santé des Autochtones
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
PATERSON, Barbara L
University of New Brunswick (Fredericton) LEBLANC, Denis / LOPPIE READING, Charlotte J / MOORE, Carla S / WIEN, Frederic C
 $102,347 ABH 2 Yr(s)
"Talking with their feet": Origins and impact of and potential solutions to non-attendance in diabetes clinics by Aboriginal people
SMITH, Dawn A
University of Ottawa ANDREW, Caroline P / EDWARDS, Nancy C / PETERSON, Wendy
 $65,682 ABH 2 Yr(s)
Improving access to preventive early childhood services for urban Aboriginal families: A participatory research study
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
1
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Aging / Vieillissement
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
CHERTKOW, Howard M
Jewish General Hospital (Montreal) EVANS, Alan C / THIEL, Alexander / WHATMOUGH, Christine E
 $149,843 BSB 3 Yr(s)
Lady Davis Institute for Medical Research (Mtl)
Diagnosis, localization, and treatment of semantic memory impairment in Alzheimer's Disease
CLARK, Alexander M
University of Alberta CHAN, Michael C / EZEKOWITZ, Justin A / KASZA, Leslie A / MCALISTER, Finlay A / STRAIN, Laurel A / TSUYUKI, Ross T
 $88,802 HSI 2 Yr(s)
Improving heart failure outcomes in rural communities: Moving from understanding to practice change
GIGNAC, Monique A
University Health Network (Toronto) BACKMAN, Catherine L / BADLEY, Elizabeth M / DAVIS, Aileen M / LACAILLE, Diane V
 $104,634 SDA 2 Yr(s)
Measuring What Matters in Life: Patterns of Role Participation in Arthritis
GIROUARD, Hélène
Université de Montréal $121,688 CSC 3 Yr(s)
Astrogliosis in Angiotensin II-induced neurovascular uncoupling.
GOTTLIEB, Benjamin H
University of Guelph MAITLAND, Scott B / MEEGAN, Daniel / SPRIET, Lawrence L
 $107,084 SDA 3 Yr(s)
Contribution of Volunteer Service to the Physical Fitness and Cognitive Functioning of Older Adults: A Prospective, Comparison Study
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
2
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Aging / Vieillissement
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
HARKNESS, Troy A
University of Saskatchewan $86,692 BCA 3 Yr(s)
Mechanisms facilitating Anaphase Promoting Complex-dependent lifespan in yeast
HASHER, Lynn
Baycrest Centre for Geriatric Care (Toronto) GRADY, Cheryl L $98,511 BSC 3 Yr(s)
Rotman Research Institute (Toronto, Ontario)
Aging and Memory: Behavoural and Neural Underpinnings of Memory Failure
HOOD, David A
York University (Toronto, Ontario) $105,687 BCA 4 Yr(s)
Mitochondria in aging skeletal muscle
JUNOP, Murray S
McMaster University $130,841 BMA 5 Yr(s)
Unraveling the Molecular Mechanisms of Non-homologous DNA End-joining
KHALIL, Abdelouahed
Université de Sherbrooke CUNNANE, Stephen / GRENIER, Guillaume
 $105,131 BCA 4 Yr(s)
Centre de recherche sur le vieillissement (QC)
Mécanismes d'action des paraoxonases 1 et 3 dans la régulation des propriétés anti- athérogènes des HDL au cours du vieillissement
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
3
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Aging / Vieillissement
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
MAYSINGER, Dusica
McGill University $99,674 PS 3 Yr(s)
NANOMEDICINES: A Non-Invasive Approach to Neural Sensing, Imaging, and Chaperoning in the Compromised Nervous System
MCELHANEY, Janet E
University of British Columbia KOLLMANN, Tobias R / MENEILLY, Graydon S
 $128,802 BCA 3 Yr(s)
Vancouver Coastal Health Research Institute
Inflammaging, Diabetes & Metabolic Sydrome: Effect on T-Cell Responses to Influenza
PAUDEL, Hemant K
Jewish General Hospital (Montreal) $134,809 BCA 3 Yr(s)
Tau protein and Alzheimer's disease
PRADO, Vania F
University of Western Ontario PRADO, Marco A $164,525 BCA 5 Yr(s)
The role of basal forebrain cholinergic neurons in synaptic plasticity and cognition.
RAJAH, Maria N
Douglas Hospital Research Centre (Verdun, Québec)
 GRADY, Cheryl L / PRUESSNER, Jens C
 $86,882 BCA 3 Yr(s)
Dissociating regional changes in prefrontal cortex structure and function that impact memory performance during normal aging
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
4
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Aging / Vieillissement
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
ROBAIRE, Bernard
McGill University NAGANO, Makoto $148,322 E 5 Yr(s)
Aging of male germ cells
SADIKOT, Abbas F
McGill University $131,897 MOV 5 Yr(s)
Montreal Neurological Institute
Mechanisms by which Afferents Regulate Striatal Neuronal Loss and Motor Activity in Movement Disorders
SHATENSTEIN, Bryna
Institut universitaire de gériatrie de Montréal GAUVIN, Lise / KELLER, Heather H / PAYETTE, Hélène / RICHARD, Lucie
 $56,877 SDA 1 Yr(s)
The impact of personal characteristics and social factors on food choices and adaptive strategies for maintaining diet quality among community-dwelling older adults
SHERWIN, Barbara B
McGill University $70,089 BCA 4 Yr(s)
Estrogen and Cognitive Aging in Women: A Test of the Critical Period Hypothesis
SINAL, Christopher J
Dalhousie University (Nova Scotia) $138,982 BCA 3 Yr(s)
Chemerin/CMKLR1: A Molecular Switch to Regulate Bone Marrow Adipogenesis and Osteoblastogenesis
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
5
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Aging / Vieillissement
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
STOLEE, Paul
University of Waterloo (Ontario) BERG, Katherine O / BYRNE, Kerry / CHESWORTH, Bert M / COOK, Richard J / EGAN, Mary Y / FORBES, Dorothy A / HIRDES, John P / JAGLAL, Susan B / POSS, Jeff W / WELLS, Jennie / ZHU, Mu
 $127,524 HSI 2 Yr(s)
Enhancing home care rehabilitation through better use of health information
TANNENBAUM, Cara
Institut universitaire de gériatrie de Montréal BELLEVILLE, Sylvie N / MULSANT, Benoit H
 $129,482 BCA 5 Yr(s)
Querying cognition and pharmacologic treatment of urinary incontinence in the elderly
THORIN, Eric
Montreal Heart Institute FERLAND, Guylaine / HAMEL, Edith
 $115,163 CSC 3 Yr(s)
Risk factors for cardiovascular diseases and cerebrovascular function
THORIN, Eric
Montreal Heart Institute $149,289 PT 5 Yr(s)
Ageing of the vascular endothelium
WELLINGTON, Cheryl L
University of British Columbia DONKIN, James / FAN, Jianjia
 $187,482 BCA 5 Yr(s)
Child and Family Research Institute
The role of ABCA1 and apolipoprotein E in brain lipid metabolism and amyloidogenesis
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
6
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Cancer Research / Cancer
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
BALLY, Marcel B
University of British Columbia APARICIO, Samuel J / JONES, Steven / LASKIN, Janessa J / MARRA, Marco A
 $159,178 CPT 3 Yr(s)
BC Cancer Agency (Vancouver, BC)
SynTarg Discovery Program: Use of a Genome Wide siRNA Screen To Identify Targets that will Enhance Platinum-Containing Chemotherapy when used in First Line Therapy of Non-Small Cell Lung Cancer
BEDELL, Barry J
McGill University EVANS, Alan C / PIKE, G. Bruce / ROSA-NETO, Pedro / STANIMIROVIC, Danica
 $158,224 MPI 4 Yr(s)
Montreal Neurological Institute
Multi-parametric imaging studies of novel therapeutic agents in rodent models of glioma
BERGER, Stuart A
University Health Network (Toronto) $104,799 CPT 3 Yr(s)
Calpain and calpastatin in leukemia
BRAND, Marjorie C
Ottawa Health Research Institute $149,655 CBT 3 Yr(s)
Epigenetic Regulation of Erythropoiesis by the MLL Family of Proto-oncogenes
CASPER, Robert F
Mount Sinai Hospital (Toronto) BROWN, Theodore J / SHAPIRO, Colin M
 $143,607 E 3 Yr(s)
Samuel Lunenfeld Research Institute (Toronto)
Prevention of Circadian Rhythm Disruption by Nocturnal Light Exposure
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
7
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Cancer Research / Cancer
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
CHARTRAND, Pascal
Université de Montréal $121,819 MCC 4 Yr(s)
Telomerase trafficking and maintenance of genome integrity
DICK, Frederick A
University of Western Ontario $118,193 CBT 3 Yr(s)
London Health Sciences Centre (London, Ontario)
Differential control of E2F transcription factors by pRB in normal and cancer cells
DROBETSKY, Elliot A
Hôpital Maisonneuve-Rosemont (Montréal) $116,014 CBT 3 Yr(s)
Cell cycle-specific regulation of nucleotide excision repair in human cells
DUBOIS, Claire M
Université de Sherbrooke $133,673 MCC 3 Yr(s)
Furin trafficking in cancer invasion and metastasis
DUGGLEBY, Wendy
WILLIAMS, Allison M
COOPER, Dan / HAMPTON, Mary R / HOLTSLANDER, Lorraine F / MACLEAN, Michael / POPKIN, David R / THOMAS- MACLEAN, Roanne Leigh / WILSON, Donna M
 $81,573 PLC 3 Yr(s)
University of Saskatchewan
Living with Hope: Developing a Psychosocial Supportive Program for Rural Older Women Caregivers of Spouses with Advanced Cancer
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
8
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Cancer Research / Cancer
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
DUROCHER, Daniel
Mount Sinai Hospital (Toronto) $157,689 MCC 5 Yr(s)
Deciphering a novel ubiquitin-dependent signaling pathway during the DNA damage response
EGAN, Sean E
Hospital for Sick Children (Toronto) ZACKSENHAUS, Eldad $147,008 MCC 4 Yr(s) Pending
Genetic Analysis of Jagged & Notch1, genes implicated in aggressive breast cancer
EVANS, Stephen V
University of Victoria (British Columbia) $123,281 BMA 5 Yr(s)
Structure-function studies of glycosyltransferases
FOSTER, F. S
Sunnybrook Health Sciences Centre BURNS, Peter N / GOERTZ, David E / KERBEL, Robert S
 $104,977 MPI 5 Yr(s)
High frequency ultrasound molecular imaging with applications in angiogenesis and preclinical cancer research.
GAUDREAULT, René C
Université Laval PETITCLERC, Eric $128,742 PS 5 Yr(s)
Hôpital Saint-François d'Assise (Québec)
Aryl 2-chloroethylureas as thioredoxin and cellular redox homeostasis inhibitors: Structure-activity relationships and mechanisms of anticancer activity
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
9
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Cancer Research / Cancer
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
GUÉRIN, Brigitte
BENARD, Francois
APARICIO, Samuel J / RUTH, Thomas J
 $108,186 CBT 3 Yr(s)
Université de Sherbrooke
Radiolabelled peptides to improve cancer diagnosis by positron emission tomography / Peptides radiomarqués pour améliorer le diagnostic du cancer par tomographie à émission de positron
HACK, Thomas F
University of Manitoba DEGNER, Lesley F / GRENIER, Debjani / LATOSINSKY, Steven / RUETHER, Joseph D / WEIR, Lorna
 $112,793 KTE 3 Yr(s)
Addressing "evidence" and "context" to facilitate the transfer and uptake of consultation recording use in oncology: A knowledge translation implementation study
HAMMOND, James R
University of Western Ontario $100,843 PT 3 Yr(s)
Structure-Function Analysis of Drug Interactions with Nucleoside Transporters
HASINOFF, Brian B
University of Manitoba $129,961 PS 3 Yr(s)
Structure-based targeting of topoisomerase II
JABADO, Nada
The Research Institute of the McGill University Health Centre
 $126,779 CPT 3 Yr(s)
Montreal Children's Hospital Research Institute
Identification and characterization of genes involved in the genesis and progression of pediatric astrocytomas.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
10
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Cancer Research / Cancer
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
JEAN-CLAUDE, Bertrand J
McGill University $98,685 CPT 3 Yr(s)
Royal Victoria Hospital (Montreal)
Single molecules engineered for the tandem delivery of Xeloda ® and EGFR/Her2 tyrosine kinase inhibitors: a novel multitargeted approach for the therapy of advanced breast cancers
JOLICOEUR, Paul
Institut de recherches cliniques de Montréal $126,721 MCC 5 Yr(s)
Oncogenes and the interaction of retroviruses with the host
KARSAN, Aly
University of British Columbia $159,805 EM 5 Yr(s)
B.C. Cancer Research Centre (Vancouver)
Innate immune signaling in hematopoiesis
KASSOUF, Wassim
The Research Institute of the McGill University Health Centre
 LAPOINTE, Jacques / MANSURE, Jose J
 $128,945 CPT 3 Yr(s)
Interrogating the mTOR Signaling Pathway in Bladder Cancer
LAPOINTE, Réjean
Centre Hosp. de l'Université de Montréal (CHUM)
 PICCIRILLO, Ciriaco A $138,780 CBT 3 Yr(s)
Defining immunological checkpoints to enhance cancer immunotherapy
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
11
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Cancer Research / Cancer
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
LE, Xiaochun C
University of Alberta WEINFELD, Michael $128,871 CBT 3 Yr(s)
Mechanisms of arsenic carcinogenesis
LEE, Stephen
University of Ottawa COTE, Jocelyn $149,124 CBM 5 Yr(s)
Anaerobic Nucleolar Proteome Dynamics
LEE, Stephen
University of Ottawa $158,919 MCC 5 Yr(s)
Understanding the HIF2a Oncogenic Pathway in Human Cancer
LEPAGE, Martin
Université de Sherbrooke ESCHER, Emanuel / GUÉRIN, Brigitte / NEUGEBAUER, Witold A / PAQUETTE, Benoît
 $133,333 MPI 3 Yr(s)
Optimization and characterization of novel contrast agents for magnetic resonance imaging allowing the non-invasive detection of matrix metalloproteinases activity in vivo
LEVESQUE, Eric
Université Laval $125,387 IT 3 Yr(s)
Hematopoietic stem cell (HCT) transplantation: Identification of key determinants of graft-versus-host disease.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
12
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Cancer Research / Cancer
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
LIN, Sheng-Xiang
Université Laval POIRIER, Donald $125,715 E 5 Yr(s)
Centre hospitalier de l'Université Laval (Québec)
Estrogenic 17beta-hydroxysteroid dehydrogenases contributing to breast cancer stimulation: 3D-structure, function and inhibition
LIU, Fei-Fei
University Health Network (Toronto) HUI, Angela B / O'SULLIVAN, Brian / PEREZ-ORDONEZ, Bayardo / PINTILIE, Melania
 $150,500 CPT 5 Yr(s)
The Role of Micro-RNA's in Human Nasopharyngeal Carcinoma
LIU, Johne X
Ottawa Health Research Institute $147,559 MCC 5 Yr(s)
Cdc42 Regulates Asymmetric Cytokinesis in Polar Body Extrusion
MACAULAY, Calum E
University of British Columbia LANE, Pierre / POH, Catherine / ROSIN, Miriam P
 $87,394 BME 3 Yr(s)
B.C. Cancer Research Centre (Vancouver)
Development and evaluation of in vivo confocal imaging of the oral mucosa: Applications in oral cancer screening, diagnosis and surveillance
MAI, Sabine
University of Manitoba $98,978 MCC 3 Yr(s)
The role of chromosome 11 in v-abl/myc- induced mouse plasmacytomagenesis
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
13
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Cancer Research / Cancer
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
MASSEY, Thomas E
Queen's University (Kingston, Ontario) $163,452 PS 5 Yr(s)
Biotransformation and Molecular Toxicity of Pulmonary Carcinogens
MES-MASSON, Anne-Marie
Centre Hosp. de l'Université de Montréal (CHUM)
 PROVENCHER, Diane M / TONIN, Patricia N
 $150,500 CPT 5 Yr(s)
Selection and validation of target genes implicated in the clinical and biological features of ovarian cancer
MULLER, William J
McGill University $128,630 MCC 5 Yr(s)
The role of phosphatidylinositol-3 kinase (PI3K) coupled signaling pathways in mammary tumorigenesis
OHH, Michael
University of Toronto $110,596 CBM 5 Yr(s)
Role of HIF in Endocytosis
PAQUETTE, Benoît
Université de Sherbrooke BUJOLD, Rachel / LEPAGE, Martin
 $88,626 CPT 3 Yr(s)
Improving radiotherapy of breast cancer with the COX-2 inhibitor NS-398
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
14
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Cancer Research / Cancer
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
PARISSENTI, Amadeo M
Sudbury Regional Hospital (ON) CHAPMAN, Judith-Anne W / CONLON, Michael / KAHN, Harriette / MACLEAN, Dave A / TRUDEAU, Maureen E
 $111,280 CPT 3 Yr(s)
Aldoketoreductases and Their Role in Tumour Progression and Anthracycline Resistance in Human Breast Cancer
POSTOVIT, Lynne-Marie
University of Western Ontario $127,001 MCC 5 Yr(s)
Role of Oxygen as a Regulator of Tumour Cell Plasticity and Metastatic Potential
ROBERT, François
Institut de recherches cliniques de Montréal COULOMBE, Benoît $137,699 GMX 1 Yr(s)
Systematic characterization of the proteome associated with specific genomic loci: A proof of concept
ROSEN, Kirill V
Dalhousie University (Nova Scotia) LEE, Patrick W $112,459 MCC 3 Yr(s)
Anti-apoptotic mechanisms that mediate ras oncogene-driven tumor growth
ROSKELLEY, Calvin D
University of British Columbia MCNAGNY, Kelly M $111,112 CPT 4 Yr(s)
The role of the podocalyxin complex in tumor progression.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
15
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Cancer Research / Cancer
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
SABISTON, Catherine M
McGill University O'LOUGHLIN, Jennifer L / WROSCH, Carsten
 $144,118 PSB 3 Yr(s)
Physical activity among breast cancer survivors: Understanding the impact on biological risk factors and psychological health over time.
SADAR, Marianne D
University of British Columbia ANDERSEN, Raymond J / WANG, Yuzhuo
 $151,203 E 3 Yr(s)
B.C. Cancer Research Centre (Vancouver)
Discovery of new drug candidates for the clinical management of prostate cancer
SHAH, Girish M
Université Laval GRAZIANI, Grazia / PASIEKA, Janice L
 $156,347 CBT 4 Yr(s)
Centre hospitalier de l'Université Laval (Québec)
Potentiation of chemotherapy of neuroendocrine carcinoid tumors by PARP- inhibitors
SLEIMAN, Hanadi
McGill University AUTEXIER, Chantal / MOITESSIER, Nicolas R
 $103,673 CBT 3 Yr(s)
Supramolecular Complexes as G-Quadruplex Binders: Towards Effective Telomerase Inhibition
ST-PIERRE, Yves
INRS - (Québec, QC) $97,633 CPT 3 Yr(s)
INRS-Institut Armand-Frappier (Laval)
The role of galectin-7 in mammary tumorigenesis and metastasis
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
16
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Cancer Research / Cancer
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
TANNOCK, Ian F
University Health Network (Toronto) $127,822 CPT 3 Yr(s)
Princess Margaret Hospital (Toronto)
Repopulation and chemotherapy
THOMPSON, Alison
Dalhousie University (Nova Scotia) $113,449 PS 3 Yr(s)
Design, Synthesis and Evaluation of Prodigiosin Analogues as Chemotherapeutic Agents
TRUONG, Kien K
University of Toronto $66,437 BME 3 Yr(s)
Live cell imaging of caspase specific kinetics using fluorescent protein biosensors
TRUS, Micheal R
McMaster University SINGH, Gurmit $123,934 CPT 1 Yr(s)
Juravinski Cancer Centre (Hamilton, ON)
Identification of Targets for Novel Acute Myeloblastic Leukemia Treatments
URBACH, David R
University Health Network (Toronto) BAXTER, Nancy N / LIX, Lisa M / SIMUNOVIC, Marko / SUTRADHAR, Rinku
 $209,445 HSR 5 Yr(s)
Structures and Processes of Care in Colorectal Cancer Surgery (SPoCCS) Study
VERREAULT, Alain
Université de Montréal $138,426 BMB 5 Yr(s)
Chromatin Assembly during DNA Replication
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
17
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Cancer Research / Cancer
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
WAGNER, James R
Université de Sherbrooke CADET, Jean $107,402 CBT 3 Yr(s)
DNA repair and mutagenic potential of oxidized cytosine and 5-methylcytosine
XIANG, Jim (Jianhua)
University of Saskatchewan $123,201 PS 4 Yr(s)
CD4+ T-Cell vaccine capable of breaking immune tolerance, A novel anti-cancer pharmaceutical.
ZENG, Haishan
LAM, Stephen $78,013 MPI 4 Yr(s)
University of British Columbia
B.C. Cancer Research Centre (Vancouver)
Rapid Multi-spectral Imaging of Tissue Physiological and Morphological Changes for Endoscopic Lung Cancer Detection and Localization
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
18
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Circulatory and Respiratory Health / Santé circulatoire et respiratoire
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
BACKX, Peter H
University Health Network (Toronto) $146,346 CSA 5 Yr(s)
Mechanisms for (subcellular) regulation of cAMP in normal and diseased heart
BONNET, Sébastien
University of Alberta $118,500 CSC 5 Yr(s)
Experimental therapies for vascular remodeling diseases
BUTCHER, Kenneth S
University of Alberta BEAULIEU, Christian / EMERY, Derek J / JEERAKATHIL, Thomas J / MAJUMDAR, Sumit R / SHUAIB, Ashfaq
 $88,926 CSB 3 Yr(s)
Cerebral Perfusion and Blood Pressure in Acute Ischemic Stroke.
CHALIFOUR, Lorraine E
Jewish General Hospital (Montreal) SEBAG, Igal A $108,035 CSB 5 Yr(s)
Steroidal hormone programming in heart.
COUTTS, Shelagh B
University of Calgary DEMCHUK, Andrew M / ELIASZIW, Michael / FRAYNE, Richard / GOYAL, Mayank / HILL, Michael D
 $122,798 CSC 3 Yr(s)
CT And MRI in the Triage of TIA and minor Cerebrovascular events to identify High risk patients. (CATCH)
CYBULSKY, Myron I
University Health Network (Toronto) $146,813 CSC 5 Yr(s)
Functions of alpha-4 integrins in monocyte emigration.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
19
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Circulatory and Respiratory Health / Santé circulatoire et respiratoire
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
DENG, Alan Y
Centre Hosp. de l'Université de Montréal (CHUM)
 DEBLOIS, Denis $136,265 CSB 3 Yr(s)
Gene discovery for cardiovascular diseases independent of hypertension
DIXON, Ian Michael C
University of Manitoba $102,611 CSC 5 Yr(s)
Regulation of extracellular matrix by myofibroblasts in cardiac hypertrophy and failure
FISET, Céline
Montreal Heart Institute $170,966 CSA 5 Yr(s)
Sex hormone-based differences in cardiac electrical activity
FISET, Céline
Montreal Heart Institute $156,739 CP 5 Yr(s)
The role of pro-inflammatory cytokines on cardiac repolarization and arrhythmogenesis
GOBEIL, Fernand J
Université de Sherbrooke $104,038 PT 4 Yr(s)
Probing signalling and biological outcomes of nuclear bradykinin receptors.
GOLLOB, Michael H
University of Ottawa $115,982 CSB 3 Yr(s)
University of Ottawa Heart Institute
Connexin Defects and Mechanistic Insight into the Vunerability of Atrial Fibrillation
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
20
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Circulatory and Respiratory Health / Santé circulatoire et respiratoire
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
GREER, John J
University of Alberta $134,934 RS 5 Yr(s)
Ampakine Therapy to Alleviate Respiratory Depression
GUILLEMETTE, Gaétan
Université de Sherbrooke ESCHER, Emanuel / LAVIGNE, Pierre / LEDUC, Richard
 $131,597 PT 5 Yr(s)
Bases moléculaires de la fonction du récepteur AT1 de l'angiotensine II
HAMET, Pavel
Centre Hosp. de l'Université de Montréal (CHUM)
 ORLOV, Sergei N / SEDA, Ondrej
 $164,614 CSB 5 Yr(s)
Hypertension at nexus of the thrifty, thirsty and accelerated ageing genotypes: evolution of a complex disease
KARSAN, Aly
University of British Columbia $141,043 CSA 5 Yr(s)
B.C. Cancer Research Centre (Vancouver)
Endothelial to mesenchymal transformation
KIRSHENBAUM, Lorrie A
University of Manitoba $145,266 CSA 5 Yr(s)
Molecular Determinants of Apoptosis in Heart
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
21
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Circulatory and Respiratory Health / Santé circulatoire et respiratoire
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
LAVOIE, Kim
Montreal Heart Institute ARSENAULT, André / BACON, Simon L / DUPUIS, Jocelyn / PILOTE, Louise / VADEBONCOEUR, Alain
 $85,235 POP 4 Yr(s)
6 Mths
Improving prediction of cardiovascular morbidity and mortality in men and women using a new nuclear imaging technique designed to assess endothelial function by vascular reactivity
LEONG-POI, Howard M
St. Michael's Hospital (Toronto) DICK, Alexander J / STEWART, Duncan J
 $132,926 MPI 3 Yr(s)
Molecular Imaging of Stem Cell Therapy Using Targeted Contrast Ultrasound
LIU, Mingyao
University Health Network (Toronto) $142,782 RS 5 Yr(s)
Signal crosstalk in lung injury and repair
LOPASCHUK, Gary D
University of Alberta $124,577 CSB 5 Yr(s)
Energy substrate metabolism in the ischemic and non-ischemic heart
MCNEILL, John H
University of British Columbia $131,174 CSB 3 Yr(s)
Malonyl CoA-Independent Regulation of Carnitine Palmitoyltransferase-1 by ß adrenoceptor Signalling in the Heart
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
22
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Circulatory and Respiratory Health / Santé circulatoire et respiratoire
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
MOQBEL, Redwan
University of Alberta LACY, Paige $154,500 RS 5 Yr(s)
Intracellular Mechanisms in Eosinophil Exocytosis: Contribution to the Development of Airway Inflammation.
MOURAD, Walid M
Centre Hosp. de l'Université de Montréal (CHUM)
 HASSAN, Ghada / MERHI, Yahye
 $129,817 CSC 5 Yr(s)
Role of CD40 ligand in athero-thrombosis.
NANTHAKUMAR, Kumaraswamy
University Health Network (Toronto) $136,187 CSB 5 Yr(s)
Mechanisms and Modulation of Spatio- temporal Organization of Human Ventricular Fibrillation
NOSKOV, Sergei
University of Calgary DUFF, Henry J $90,743 CSA 3 Yr(s)
Mechanism of the high-affinity ligand binding and selective ion permeation in voltage-gated K-channels
PARENT, Jean-Luc
Université de Sherbrooke $141,943 CP 5 Yr(s)
Regulation of G protein-coupled receptor trafficking
POWELL, William S
McGill University $143,165 PT 5 Yr(s)
Biosynthesis and role of eicosanoids in inflammation
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
23
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Circulatory and Respiratory Health / Santé circulatoire et respiratoire
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
REUDELHUBER, Timothy L
Institut de recherches cliniques de Montréal $125,214 CSB 3 Yr(s)
Prorenin in health and disease
RUEL, Marc
SUURONEN, Erik DE KEMP, Robert A / GRIFFITH, May C / STEWART, Duncan J / WHITMAN, Stewart C
 $149,827 BME 4 Yr(s)
University of Ottawa
University of Ottawa Heart Institute
Mechanisms of Progenitor Cell-based Angiogenic Therapy with Tissue-Engineered Biopolymer Delivery Matrices and Effects of Host Substrate Modification
SERIES, Frédéric H
Université Laval SIMILOWSKI, Thomas $120,310 RS 5 Yr(s)
Institut universitaire de cardiologie et pneumologie de Québec
Pathophysiology of sleep disordered breathing
THOMAS, David Y
McGill University CARLILE, Graeme W / HANRAHAN, John W / ROBERT, Renaud S
 $114,036 RS 5 Yr(s)
Mechanisms of correction of deltaF508CFTR
VON DER WEID, Pierre-Yves
University of Calgary $137,832 EM 5 Yr(s)
Mechanisms of Distension-Activated Contractility in Lymphatic Vessels: Importance for edema resolution
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
24
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Circulatory and Respiratory Health / Santé circulatoire et respiratoire
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
VON HARSDORF, Rudiger
University Health Network (Toronto) $151,886 CSA 5 Yr(s)
Cardiac growth control by E2F4
WARD, Michael E
BACKX, Peter H $129,900 CSB 3 Yr(s)
St. Michael's Hospital (Toronto)
Oxygen Regulation of Membrane Potential by a GTP-gated Chloride Current in Proliferating Pulmonary Artery Smooth Muscle.
YAN, Andrew T
WALD, Ron
DICK, Alexander J / GOLDSTEIN, Marc / LEONG-POI, Howard M / WU, Louis
 $101,376 CSB 3 Yr(s)
St. Michael's Hospital (Toronto)
Impact of in-centre nocturnal hemodialysis on ventricular remodeling and function in end- stage renal disease
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
25
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Gender and Health / Santé des femmes et des hommes
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
BAILLARGEON, Raymond H
University of Ottawa KEENAN, Kathryn / LEFEBVRE, Francine
 $60,000 GSH 2 Yr(s)
The Origins of Gender Differences in Disruptive Behavior Problems II
BERGERON, Sophie
Université du Québec à Montréal BINIK, Yitzchak Irving M / DUPUIS, Marie- Josée / KHALIFE, Samir
 $59,988 PSB 4 Yr(s)
Dyadic predictors of pain and related sexual impairment in women with vulvodynia: A prospective investigation
BERMAN, Helene A
MASON, Robin A CLASSEN, Catherine C / LANIUS, Ruth A / MACARTHUR-EVANS, Marilyn K / RODGER, Susan C / ROSS, Lori E
 $73,920 GSH 3 Yr(s)
University of Western Ontario
Embodied Trauma: The Influence of Past Trauma on Women During the Transition to Motherhood
BERNARD, Daniel J
McGill University BOERBOOM, Derek Theodoor
 $159,619 GSH 5 Yr(s)
Transcriptional regulation of follicle stimulating hormone synthesis
FORTIER, Michel A
Université Laval EL-ALFY, Mohamed $114,506 CIA 3 Yr(s)
Centre hospitalier de l'Université Laval (Québec)
Genes and proteins of the prostaglandin sythesis and signalling cascades associated with menstrual disorders
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
26
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Gender and Health / Santé des femmes et des hommes
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
GALDAS, Paul M
OLIFFE, John L
GREWAL, Sukhdev K / JOHNSON, Joy L / RATNER, Pamela A / WONG, Sabrina
 $55,905 GSH 3 Yr(s)
University of British Columbia
Unpacking the effects of gender and ethnicity on healthcare utilization: The cardiac rehabilitation experiences of Indo-Canadian Men
GRANT, Denis M
University of Toronto $119,798 GSH 3 Yr(s)
Gender, genes and risk for arylamine-induced cancers: animal models and mechanisms
KAUL, Padmaja R
University of Alberta ARMSTRONG, Paul W / GRAHAM, Michelle M / NORRIS, Colleen / WELSH, Robert C
 $131,706 GSH 3 Yr(s)
Tracking gender differences in acute coronary syndromes: At the first point of care and beyond
LETOURNEAU, Nicole L
University of New Brunswick (Fredericton) BENZIES, Karen M / DENNIS, Cindy-Lee E / DOUCET, Andrea M / DUFFETT-LEGER, Linda A / MCGRATH, Patrick J / STEWART, Miriam J
 $86,835 GSH 2 Yr(s)
Support for Fathers Affected by Postpartum Depression
VIAU, Victor
University of British Columbia $153,421 BSA 5 Yr(s)
Androgen sensitive pathways to the paraventricular nucleus of the hypothalamus
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
27
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Genetics / Génétique
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
BARR, Cathy L
University Health Network (Toronto) KERR, Elizabeth N / LOVETT, Maureen W
 $200,665 BSB 5 Yr(s)
Toronto Western Research Institute (Toronto)
Genetics of Reading Disabilities
BENNETT, Steffany A
FIGEYS, Daniel BAETZ, Kristin K $107,070 CBM 5 Yr(s)
University of Ottawa
Lipidomics of neurodegenerative disease: A systems and cell biology approach to reverse neuronal vulnerability
BERGERON, John J
McGill University NILSSON, Tommy J $264,865 CBM 5 Yr(s)
The Molecular Cytology of Membrane Dynamics
BOUDREAU, François
Université de Sherbrooke $138,284 EM 3 Yr(s)
Functional role of specific transcriptional regulators during intestinal epithelial development and maintenance
BRINDLEY, David N
University of Alberta $144,853 CSA 5 Yr(s)
Control of cardiac fatty acid and glucose metabolism by lipins
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
28
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Genetics / Génétique
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
CARRENO, Sébastien
Université de Montréal $132,683 CBM 5 Yr(s)
Institute for Research in Immunology and Cancer (Montreal, QC)
Role of the Phosphoinositides and Moesin on the Actin/Microtubule crosstalk during cell division.
CARRIER, Julie
Université de Sherbrooke $101,558 EM 3 Yr(s)
The role of the estrogen-related receptors alpha (ERRalpha) in the normal and cancerous intestine
CHEN, Xing-Zhen
University of Alberta $140,382 EM 5 Yr(s)
Polycystin-2: cellular function, regulation and mechanism of renal cyst progression
CHTEINBERG, Serguei V
Université de Montréal $108,876 BMB 5 Yr(s)
Exploring the mechanisms of alternative reading of genetic code
CHUA, Gordon
University of Calgary $129,473 GMX 5 Yr(s)
Deciphering pathways of transcriptional regulation in Schizosaccharomyces pombe
CROSS, James C
University of Calgary $193,149 E 5 Yr(s)
Biology of Trophoblast Giant Cells
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
29
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Genetics / Génétique
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
DALEY, Denise
University of British Columbia $135,397 RS 3 Yr(s)
St. Paul's Hospital, Vancouver
The Genetics of Asthma, Atopy and Allergic Diseases
DAVIE, James R
University of Manitoba $159,827 BMB 5 Yr(s)
Histone modifications and the epigenetic state of transcribed chromatin
DICK, John E
University Health Network (Toronto) $161,250 EM 5 Yr(s)
Molecular and cellular characterization of early human hematopoietic lineage determination
DUNN, Stanley D
University of Western Ontario $140,014 BMA 5 Yr(s)
Energy Coupling in ATP Synthase
EDWARDS, Aled M
University of Toronto MAXWELL, Karen L $275,786 GMX 5 Yr(s)
Functional and Structural Genomics of Bacteriophage
GLOVER, John Newman M
University of Alberta $154,097 BMA 5 Yr(s)
Regulation of Bacterial Conjugation
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
30
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Genetics / Génétique
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
GRUENHEID, Samantha L
McGill University $113,468 G 5 Yr(s)
Genetic dissection of the host response to intestinal infections
HEKIMI, Siegfried
McGill University $104,712 DEV 3 Yr(s)
Genetics of lipoprotein metabolism in C. elegans
HOLCIK, Martin
Children's Hospital of Eastern Ontario (Ottawa)
 $136,392 BMB 3 Yr(s)
Regulation of internal initiation of translation in cell death and survival
HUGHES, Timothy R
University of Toronto $218,492 GMX 5 Yr(s)
Comprehensive analysis of mouse and human transcription factor DNA-binding specificities
JIA, Zongchao
Queen's University (Kingston, Ontario) $160,565 BMA 5 Yr(s)
EF-hand proteins and calcium-mediated modulation
LIPSHITZ, Howard D
University of Toronto $165,858 DEV 5 Yr(s)
Post-transcriptional gene regulation during Drosophila development
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
31
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Genetics / Génétique
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
LOHNES, David L
University of Ottawa $196,495 DEV 5 Yr(s)
Novel roles for Cdx proteins in development
LORINCZ, Matthew C
University of British Columbia $148,481 G 5 Yr(s)
Analysis of the Interplay Between Histone MTases, DNA Methylation and Proviral Silencing
MAYOR, Thibault
University of British Columbia $101,424 CBM 5 Yr(s)
Proteomic Analysis of the Ubiquitin Proteasome System and the Protein Quality Control Machinery
MENEGHINI, Marc D
University of Toronto $150,524 BMB 5 Yr(s)
Functional analysis of a developmentally regulated Jumonji-family histone demethylation pathway in Saccharomyces cerevisiae.
NALBANTOGLU, Joséphine
KARPATI, George $105,136 MOV 4 Yr(s)
McGill University
Molecular therapies for dystrophin deficiency
NODWELL, Justin R
McMaster University $144,910 BMB 5 Yr(s)
Links between antibiotic production and resistance in producer organisms
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
32
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Genetics / Génétique
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
OSBORNE, Lucy R
University of Toronto $130,190 G 5 Yr(s)
Genetic analysis of Williams-Beuren syndrome: linking genes with cognition and behaviour
PAETZEL, Mark W
Simon Fraser University (Burnaby, B.C.) $156,468 BMA 5 Yr(s)
Structural analysis of the molecular machinery involved in protein secretion and membrane protein assembly.
PASTINEN, Tomi
McGill University HARVEY, Edward J / RICHARDS, Brent
 $129,000 G 3 Yr(s)
Genomewide analysis of functional polymorphisms affecting human bone phenotypes
PEI, York P
University of Toronto PATERSON, Andrew D $132,526 G 3 Yr(s)
Molecular Genetics of IgA Nephropathy
PENG, Chun
York University (Toronto, Ontario) SHAW, Patricia A $133,300 E 3 Yr(s)
The integrative role of Nodal, cyclin G2 and miR-376c in ovarian tumorigenesis
POLYCHRONAKOS, Constantin
The Research Institute of the McGill University Health Centre
 $143,250 G 3 Yr(s)
Novel genetic susceptibility loci for type 1 diabetes
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
33
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Genetics / Génétique
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
ROGER, Andrew J
Dalhousie University (Nova Scotia) SIMPSON, Alastair G $143,876 GMX 5 Yr(s)
Major transitions in eukaryotic cell evolution.
ROKEACH, Luis A
Université de Montréal $112,338 CBM 3 Yr(s)
The endoplasmic reticulum and programmed cell death
SKAMENE, Emil
The Research Institute of the McGill University Health Centre
 FORTIN, Anny / GROS, Philippe / SLADEK, Robert G / VIDAL, Silvia M
 $199,262 G 5 Yr(s)
Genetic Dissection of Host Response Against Respiratory Virus Infections in Recombinant Congenic Strains of Mice
SRAYKO, Martin A
University of Alberta $133,672 CP 4 Yr(s)
Approaches to understand the regulation of microtubules and microtubule motor proteins in mitotic spindle assembly and the positioning of intracellular structures.
STANFORD, William L
BADER, Gary D $315,949 GMX 5 Yr(s)
MORRIS, Quaid D
ZANDSTRA, Peter W
University of Toronto
Transcription Networks Controlling Human Embryonic Stem Cell Fate
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
34
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Genetics / Génétique
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
TANENTZAPF, Guy
University of British Columbia $112,864 CP 4 Yr(s)
Analysis of Integrin Function in Muscle Formation and Maintenance.
TEPASS, Ulrich
University of Toronto $172,854 CP 5 Yr(s)
Regulation of epithelial polarity
WEEKS, Gerald
University of British Columbia $146,176 CP 5 Yr(s)
The role of Rap1 in regulating cell function
WEINER, Joel H
University of Alberta $114,626 BMA 5 Yr(s)
Bacterial complex II homologs as models for mitochondrial electron transfer
WEKSBERG, Rosanna
Hospital for Sick Children (Toronto) ROBERTS, Sheila (Wendy) G / SCHERER, Stephen W
 $186,196 G 3 Yr(s)
Genome-Wide DNA Methylation Profiling in Autism
WILKINSON, Mark D
University of British Columbia MCMANUS, Bruce M $133,178 GMX 4 Yr(s)
St. Paul's Hospital, Vancouver
CardioSHARE: Design of an integrated query and analysis framework for ischemic heart disease data
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
35
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Genetics / Génétique
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
WOOD, Janet M
University of Guelph $84,731 CP 3 Yr(s)
Characterization of osmolytes and osmolyte transporters that confer osmotic, thermal, oxidative and urea stress tolerance on Escherichia coli cells
ZACKSENHAUS, Eldad
University Health Network (Toronto) $149,253 CBM 5 Yr(s)
Effect of pRb phosphorylation on development and disease
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
36
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Health Services and Policy Research / Services et politiques de la santé
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
AHMED, Sara
McGill University BARTLETT, Susan J / ERNST, Pierre-Paul / GRAD, Roland M / PARÉ, Guy / PERREAULT, Robert / PINSONNEAULT, Alain / TAYLOR, Laurel K
 $69,898 KTE 2 Yr(s)
6 Mths
Facilitating patient self-management in chronic disease: Integrating electronic personal health records and ongoing communication into a web-based self-management tool
BAYOUMI, Ahmed M
St. Michael's Hospital (Toronto) ANTONIOU, Tony / HOCH, Jeffrey S / PARK-WYLLIE, Laura / STRIKE, Carol J / TABACK, Nathan A
 $130,723 HSR 2 Yr(s)
Preference Measures for HIV Antiretroviral Decision Making
BELL, Chaim M
St. Michael's Hospital (Toronto) BIERMAN, Arlene S / BRONSKILL, Susan E / ETCHELLS, Edward E / FERNANDES, Olavo A / MAMDANI, Muhammad / ROCHON, Paula A / URBACH, David R
 $63,057 HSR 3 Yr(s)
Unintentional discontinuation of chronic medications for seniors in long-term care facilities: An evaluation of a medication reconciliation and quality improvement strategy
BELL, Scott M
University of Saskatchewan MUHAJARINE, Nazeem / RAMSDEN, Vivian R / WILSON, Kathleen J
 $98,414 HSI 3 Yr(s)
Examining Access to Health Care at the Neighbourhood Level
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
37
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Health Services and Policy Research / Services et politiques de la santé
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
COWARD, Harold G
STAJDUHAR, Kelli I
AGUPIO, Godfrey / ATTIG, Thomas W / BRUCE, W. A / CLARK, David / CLOUSTON, Joyce / DAVIES, Elizabeth M / FLORIDA, Robert E / HADLEY, Michael L / HUI, Edwin C / KAUFERT, Joseph M / NAYAR, Kamala E / RAMBACHAN, Anantanand / RAVVIN, Norman / SOSKICE, Janet C / WAUGH, Earle H
 $51,641 ELH 3 Yr(s)
University of Victoria (British Columbia)
Religious Requirements for a "Good Death" in Hospice Care
DIXON, Elijah
University of Calgary BRIEN, Susan E / GHALI, William A / SEIDEL, Judy E / SIMUNOVIC, Marko
 $145,874 HSR 3 Yr(s)
Rates and Waits for Cancer Surgery in Canada: A Mixed Method Assessment
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
38
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Health Services and Policy Research / Services et politiques de la santé
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
GRIMSHAW, Jeremy M
Ottawa Health Research Institute BROUWERS, Melissa C / DRIEDGER, S. Michelle / ECCLES, Martin P / FRANCIS, Jillian J / GODIN, Gaston / HANNA, Steven E / HUX, Janet E / JOHNSTON, Marie / LEGARE, France / LEMYRE, Louise / POMEY, Marie-Pascale A / SALES, Anne E / ZWARENSTEIN, Merrick F
 $193,768 KTE 3 Yr(s)
Canada Prime Plus: Selecting individual and organizational theories for interventions to change clinical practice
GROOTENDORST, Paul V
University of Toronto RACINE, Jeffrey S $106,370 HSR 2 Yr(s)
Assessment of the cost and equity of different catastrophic drug insurance options for Canadians
HAGGERTY, Jeannie L
FORTIN, Martin
BEAULIEU, Marie- Dominique / HUDON, Catherine / LOIGNON, Christine / PREVILLE, Michel / ROBERGE, Danièle
 $161,880 HSR 4 Yr(s)
Université de Sherbrooke
At the interface of the community and the healthcare system: a longitudinal cohort to study evolving health and the impact of primary healthcare from the patient perspective.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
39
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Health Services and Policy Research / Services et politiques de la santé
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
LEGARE, France
Université Laval ELWYN, Glyn / FROSCH, Dominick L / GRIMSHAW, Jeremy M / LABRECQUE, Michel / OUIMET, Mathieu / ROUSSEAU, Michel / STACEY, Dawn / STEWART, Moira A / VAN DER WEIJDEN, Trudy
 $108,922 KTE 2 Yr(s)
6 Mths
EXACKTE 2: Exploiting the clinical consultation as a knowledge transfer and exchange environment
LEHOUX, Pascale N
Université de Montréal DENIS, Jean-Louis / MILLER, Fiona A / URBACH, David R / WILLIAMS-JONES, Bryn
 $88,143 KTE 1 Yr(s)
6 Mths
Judgments and health innovation: How do upstream knowledge transfer and exchange among stakeholders contribute to the design of innovations
LYND, Larry D
University of British Columbia FITZGERALD, J M / LAM, Stephen / MARRA, Carlo A / SIN, Donald
 $57,628 HSR 2 Yr(s)
Evaluating the Association Between Inhaled Corticosteroid and Statin Use and the Development of Lung Cancer in COPD Patients: A Linked Health Database Study
LYND, Larry D
University of British Columbia MAIL, Walter J / MARRA, Carlo A / TAYLOR, Jeff G / TSUYUKI, Ross T
 $53,431 HPM 2 Yr(s)
Study of Understanding Patients' Preferences on Remuneration and Transition Towards Pharmacists' Provision of Chronic Disease Management (SUPPORT 2)
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
40
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Health Services and Policy Research / Services et politiques de la santé
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
MINTZES, Barbara J
LEXCHIN, Joel
BARER, Morris L / BASSETT, Kenneth L / BEAULIEU, Marie- Dominique / CASSELS, Alan K / DURRIEU, Geneviève / MORGAN, Steven G / TEJANI, Aaron M / WILKES, Michael / WRIGHT, James M
 $141,119 HPM 2 Yr(s)
University of British Columbia
Pharmaceutical sales representatives and patient safety: comparative cross-sectional survey
NATHENS, Avery B
St. Michael's Hospital (Toronto) MORRISON, Laurie J / RUBENFELD, Gordon
 $119,787 HSI 1 Yr(s)
Trauma system design: an evaluation of structure and process
POMEY, Marie-Pascale A
Université de Montréal CARPENTIER, Normand C / FOREST, Pierre- Gerlier / HUDON, Raymond / LAVIS, John N
 $76,486 HPM 3 Yr(s)
Anatomy of Quebec's Decision-Making Process: The Chaoulli Decision
ROCHON, Paula A
Baycrest Centre for Geriatric Care (Toronto) ANDERSON, Geoffrey M / BELL, Chaim M / BRONSKILL, Susan E / GRUNEIR, Andrea / SCHULL, Michael J
 $76,116 HSI 3 Yr(s)
Emergency Department Visits by Nursing Home Residents in Ontario: Descriptive Patterns of Resident Visits by Timing, Location, and Physician Availability
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
41
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Health Services and Policy Research / Services et politiques de la santé
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
SIDANI, Souraya
Ryerson University (Toronto) CAIRNEY, John / MIRANDA, Joyal / STREINER, David L
 $48,663 HSR 2 Yr(s)
Influence of Treatment Attributes on Preferences for Behavioral and Pharmacological Treatments
TALJAARD, Monica
GRIMSHAW, Jeremy M
BORUCH, Robert F / BREHAUT, Jamie C / BROWN, Judith B / DONNER, Allan / ECCLES, Martin P / SAGINUR, Raphael / ZWARENSTEIN, Merrick F
 $93,996 ELH 3 Yr(s)
WEIJER, Charles E
Ottawa Health Research Institute
Ethical and policy issues in cluster randomized trials
YU, Dickie C
University of Manitoba MARTIN, Garry L $73,509 BSB 3 Yr(s)
Improving the quality of life for people with severe and profound intellectual disabilities: Studies of choice making
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
42
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Human Development, Child and Youth Health / Développement et santé des enfants et des adolescents
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
BHATIA, Mickie
McMaster University $159,893 DEV 5 Yr(s)
Characterization of the human embryonic stem cell niche
BRESSMANN, Tim
University of Toronto KULKARNI, Gajanan V $73,178 CHI 3 Yr(s)
Tactile and visual biofeedback in the therapy of compensatory cleft palate articulation
CANIGGIA, Isabella
Mount Sinai Hospital (Toronto) JURISICOVA, Andrea / POST, Martin
 $151,410 CIA 5 Yr(s)
The role of Bcl-2 family members in regulating placental cell fate
CHAMBERS, Christine T
IWK Health Centre (Halifax) MCGRATH, Patrick J / MOORE, Christopher / MORRONGIELLO, Barbara A / YANCHAR, Natalie L
 $105,752 CHI 5 Yr(s)
Everyday Pains in Young Children
CROY, Barbara A
Queen's University (Kingston, Ontario) ADAMS, Michael A / SMITH, Graeme N
 $154,071 CIA 5 Yr(s)
Evaluation of natural killer cell contributions to the known, elevated risks for maternal and fetal pathologies in diabetic pregnancy
DAVIDGE, Sandra T
University of Alberta $112,150 CIA 5 Yr(s)
Mechanisms for cardiovascular dysfunction in offspring born intrauterine growth restricted
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
43
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Human Development, Child and Youth Health / Développement et santé des enfants et des adolescents
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
FORGET, Robert
FAUBERT, Jocelyn
GAGNON, Isabelle $137,161 CHI 5 Yr(s)
MCKERRAL, Michelle
Université de Montréal
Visual perception deficits in children after mild traumatic brain injury: psychophysics, electrophysiology and impact on postural stability
GORDON, Karen Ann
Hospital for Sick Children (Toronto) PAPSIN, Blake C $109,743 CHI 4 Yr(s)
Processing bilateral electrical input in the developing auditory system
HAMILTON, Jill K
Hospital for Sick Children (Toronto) HANLEY, Anthony J / RETNAKARAN, Ravi R / ZINMAN, Bernard
 $88,044 CHI 5 Yr(s)
Insulin resistance and beta cell dysfunction in early childhood: the role of maternal and infant metabolic risk factors
HAN, Victor Khin M
University of Western Ontario GUPTA, Madhulika B / IOSEF, Cristiana
 $155,831 E 5 Yr(s)
Regulation of Fetal Growth
HOODLESS, Pamela A
University of British Columbia $146,839 DEV 3 Yr(s)
B.C. Cancer Research Centre (Vancouver)
Formation and Patterning of the Definitive Endoderm
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
44
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Human Development, Child and Youth Health / Développement et santé des enfants et des adolescents
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
LEVY, Emile
Hôpital Sainte-Justine (Montréal) DELVIN, Edgard E $140,325 EM 5 Yr(s)
Gaining insight into cholesterol homeostasis in the small intestine: a special role for PCSK9
MURPHY, Bruce D
Université de Montréal $147,932 E 5 Yr(s)
Ovarian cell differentiation
PANG, Elizabeth W
Hospital for Sick Children (Toronto) CHEYNE, Douglas O / DE NIL, Luc F / ROBERTS, Sheila (Wendy) G
 $155,242 CHI 5 Yr(s)
Dissociating cognitive and motor components of healthy and dysfunctional expressive language development in children
ROSENBLUM, Norman D
Hospital for Sick Children (Toronto) $155,828 EM 5 Yr(s)
Control of kidney cell determination and morphogenesis by BMPs and Beta-catenin
SIDEN, Harold B
STEELE, Rose G
BRANT, Rollin F / CADELL, Susan Anne / DAVIES, Elizabeth M / STRAATMAN, Lynn
 $260,935 CHI 5 Yr(s)
University of British Columbia
Charting the Territory: Determining and Documenting Trajectories for Families Where a Child Has a Life-Threatening Condition
SNIDER, Laurie M
McGill University BOS, Arend F / MAJNEMER, Annette / MAZER, Barbara L
 $41,011 CHI 2 Yr(s)
The predictive validity of the general movements assessment of infants born preterm for functional outcomes at six years of age
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
45
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Human Development, Child and Youth Health / Développement et santé des enfants et des adolescents
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
STEVENS, Bonnie J
GIBBINS, Sharyn A
ASZTALOS, Elizabeth V / BEYENE, Joseph / HOWLETT, Alexandra A / JOHNSTON, Celeste / MCNAMARA, Patrick J / O'BRIEN, Karel / PILLAI RIDDELL, Rebecca Rita E
 $184,734 PSB 4 Yr(s)
MCGRATH, Patrick J
Hospital for Sick Children (Toronto)
Pain in Infants at risk for Neurological Impairment: A Program of Research: Phase 3
SULLIVAN, Robert
Université Laval $127,184 E 3 Yr(s)
Sperm proteins acquired during epididymal transit: functions and usefulness for diagnostic of man infertility
TRASLER, Jacquetta M
The Research Institute of the McGill University Health Centre
 NAGANO, Makoto / ZINI, Armand S
 $161,694 GSH 5 Yr(s)
Montreal Children's Hospital Research Institute
Sex-specific susceptibility for fetal origins of adult disease and transgenerational effects
UNGAR, Michael
Dalhousie University (Nova Scotia) ANDREOU, Pantelis / CARREY, Normand / DONNON, Tyrone L / LEBLANC, John C / THIESSEN, Victor
 $136,462 CHI 5 Yr(s)
Adversity and Resilience among early teens: What predicts positive outcomes in later adolescence?
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
46
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Human Development, Child and Youth Health / Développement et santé des enfants et des adolescents
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
WOODGATE, Roberta L
University of Manitoba BORTON, Barbara L / EDWARDS, Marie P / HALLMAN, Bonnie C / REMPEL, Gina R / RIPAT, Jacqueline D
 $79,768 CHI 3 Yr(s)
Changing geographies of care: Using therapeutic landscapes as a framework to understand how families with medically complex children participate in communities
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
47
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Infection and Immunity / Maladies infectieuses et immunitaires
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
ARCHAMBAULT, Jacques
Institut de recherches cliniques de Montréal $120,701 VVP 5 Yr(s)
Functions and regulation of the papillomavirus E1 and E2 proteins in the viral life cycle
ARNOLD, Donald M
McMaster University CROWTHER, Mark A / KELTON, John G / LARCHE, Mark / SNIDER, Denis P
 $109,229 IT 2 Yr(s)
The effect of rituximab on the humoral immune response to S. pneumoniae and H. influenzae type b vaccines in patients with immune thrombocytopenic purpura
AUCLAIR, Karine
McGill University MITTERMAIER, Anthony K
 $150,393 PS 3 Yr(s)
Design of inhibitors of the resistance-causing aminoglycoside N-6'-acetyltransferase
BARRY, Marie M
University of Alberta $122,077 VVP 5 Yr(s)
Poxvirus Control of Ubiquitination
BAUCH, Christopher T
GILCA, Vladimir ANONYCHUK, Andrea / COLGAN, Terence J / HOWLETT, Robbi (Roberta) / JOHN- BAPTISTE, Ava A / SANDER, Beate H
 $76,046 HSR 3 Yr(s)
KRAHN, Murray D
MAI, Verna
MCLACHLIN, Catherine (Meg) M
PHAM, Ba'
University of Guelph
Cervical cancer screening in the era of HPV vaccination: using mathematical and economic models to guide screening policy
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
48
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Infection and Immunity / Maladies infectieuses et immunitaires
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
BLEACKLEY, Robert C
University of Alberta $178,948 IT 5 Yr(s)
Lymphocyte Proteinases
BORASTON, Alisdair B
University of Victoria (British Columbia) SMITH, Steven P $169,977 BMA 5 Yr(s)
Carbohydrate-recognition in bacterial pathogenesis: structural and functional analysis of virulence-associated Clostridium perfringens enzymes.
COOMBS, Kevin M
University of Manitoba $143,507 VVP 5 Yr(s)
Structure/Function of Reovirus Core: Host Proteomic Perturbations
COUSINEAU, Benoit
McGill University OLIVIER, Martin $130,464 MI 3 Yr(s)
Development of a new generation of live vaccines using Lactococcus lactis
CYGLER, Mirek M
McGill University MATTE, Allan M / VALVANO, Miguel A
 $202,526 BMA 5 Yr(s)
Structure-Function Relationships of Bacterial Polysaccharide Co-Polymerases
DESJARDINS, Michel
Université de Montréal THIBAULT, Pierre $158,113 CBM 5 Yr(s)
The phagosome proteome and systems biology: insights into novel phagosome functions
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
49
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Infection and Immunity / Maladies infectieuses et immunitaires
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
DEVINNEY, Rebekah
University of Calgary $116,190 MI 3 Yr(s)
Subversion of host cell signalling by Vibrio parahaemolyticus
FINLAY, Barton B
University of British Columbia $170,427 MI 5 Yr(s)
Salmonella Spi 2 Type III effectors that alter host cellular functions
FLAMAND, Louis
Université Laval $118,637 VVP 5 Yr(s)
Centre hospitalier de l'Université Laval (Québec)
Shutting down the innate immune response: Mechanisms and strategies utilized by human herpesvirus 6 to persist within the infected host.
FOSTER, Leonard J
University of British Columbia $122,768 GMX 5 Yr(s)
A global view of host cell manipulation by Salmonella
GAULDIE, Jack
McMaster University $149,412 RS 5 Yr(s)
Pathogenic Mechanisms in Persistent Pulmonary Fibrosis
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
50
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Infection and Immunity / Maladies infectieuses et immunitaires
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
GRANDVAUX, Nathalie
Centre Hosp. de l'Université de Montréal (CHUM)
 $118,649 RS 5 Yr(s)
Redox regulation of the RSV-induced proinflammatory response in airway epithelial cells.
GUTTMAN, Julian A
Simon Fraser University (Burnaby, B.C.) $110,037 MI 3 Yr(s)
The Role of Endocytic Proteins at Bacteria- Induced Pedestals
KAUL, Rupert
University of Toronto GELMON, Lawrence J / KIMANI, Joshua
 $121,896 VVP 3 Yr(s)
Antiretroviral rollout in a "core transmission" group of female sex workers: impact on mucosal co-infections and predictors of HIV transmission.
LAMARRE, Alain
INRS - (Québec, QC) $128,290 VVP 3 Yr(s)
INRS-Institut Armand-Frappier (Laval)
Role of natural antibodies in promoting acquired immune responses to hepatitis C virus.
LANGLOIS, Marc-Andre
Université Laval $121,805 VVP 5 Yr(s)
Centre hospitalier de l'Université Laval (Québec)
Molecular and cellular mechanisms involved in APOBEC3G-mediated innate immunity to HIV infection
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
51
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Infection and Immunity / Maladies infectieuses et immunitaires
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
LECLERC, Denis
Université Laval LAMARRE, Alain / LAPOINTE, Réjean
 $118,736 VVP 5 Yr(s)
Centre hospitalier de l'Université Laval (Québec)
Characterization and improvement of the intrinsic adjuvant properties of papaya mosaic virus-like particles: An innovative vaccine platform.
MARTIN, Alberto
University of Toronto GOMMERMAN, Jennifer L
 $124,050 IT 4 Yr(s)
The Molecular Basis for Germinal Center Selection
MCCUSKER, Christine T
The Research Institute of the McGill University Health Centre
 $94,597 RS 3 Yr(s)
Meakins Christie Labs (Québec)
Mechanisms of tolerance induction through neonatal exposure to environmental antigens. Prevention of asthma and allergic rhinitis
MOORE, David M
MONTANER, Julio S COUTINHO, Alex G / HOGG, Robert S / KING, Rachel L / MILLS, Edward J / NABIRYO, Christine
 $139,142 POP 3 Yr(s)
University of British Columbia
Antiretroviral therapy as an additional HIV prevention tool for sero-discordant couples in Uganda
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
52
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Infection and Immunity / Maladies infectieuses et immunitaires
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
MOURAD, Walid M
Centre Hosp. de l'Université de Montréal (CHUM)
 $101,145 IT 5 Yr(s)
The impacts of disulfide bond CD40/CD40 dimers in the biological responses.
NANO, Francis E
University of Victoria (British Columbia) BORASTON, Alisdair B / GUTTMAN, Julian A
 $158,771 MI 4 Yr(s)
Type six secretion system of the Francisella Pathogenicity Island
NG, Kenneth K
University of Calgary $111,416 BMA 4 Yr(s)
Molecular structural basis of replication in medically important caliciviruses and flaviviruses
NITZ, Mark
University of Toronto $86,873 MI 3 Yr(s)
De-N-acetylases in bacterial biofilm formation: The specificity, mechanism, and inhibition of IcaB and PgaB
ROWE-MAGNUS, Dean A
Sunnybrook Health Sciences Centre $106,550 MI 4 Yr(s)
Evolution of CPS and LPS diversity in V. vulnificus
SADOWSKI, Ivan J
University of British Columbia $118,374 VVP 3 Yr(s)
Ras-responsive elements in HIV-1 replication and AIDS pathogenesis
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
53
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Infection and Immunity / Maladies infectieuses et immunitaires
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
SATO, Sachiko
Université Laval TREMBLAY, Michel J $103,384 VVP 3 Yr(s)
Centre hospitalier de l'Université Laval (Québec)
Biochemical, cellular and molecular studies to dissect the contribution of the soluble host carbohydrate binding proteins to HIV-1 pathogenesis
SEFTON, Michael V
University of Toronto WOODHOUSE, Kimberly A
 $94,540 BME 3 Yr(s)
Modular Tissue Engineering
SHERMAN, Philip M
Hospital for Sick Children (Toronto) $150,500 MI 5 Yr(s)
Epithelial cell signalling responses to attaching-effacing intestinal pathogens
SURETTE, Michael G
University of Calgary $107,666 MI 5 Yr(s)
Polymicrobial Infections and Pathogenesis of the Streptococcus Milleri Group
ZAPH, Colby
University of British Columbia $119,970 IT 5 Yr(s)
Memory TH2 cell responses during helminth infection
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
54
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Infection and Immunity / Maladies infectieuses et immunitaires
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
ZHANG, Li
University Health Network (Toronto) $177,360 IT 5 Yr(s)
Molecular Mechanisms of DN regulatory T cell-mediated donor specific transplantation tolerance.
ZUNIGA-PFLUCKER, Juan C
Sunnybrook Health Sciences Centre $137,013 IT 5 Yr(s)
Study of pre-T cell receptor signals regulating thymocyte differentiation.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
55
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Musculoskeletal Health and Arthritis / Appareil locomoteur et arthrite
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
AKIMENKO, Marie-Andrée
Ottawa Health Research Institute $138,280 DEV 5 Yr(s)
Control mechanisms of fin regeneration in zebrafish
ANTONIOU, John
Jewish General Hospital (Montreal) IATRIDIS, James / MWALE, Fackson
 $81,246 CIB 3 Yr(s)
Lady Davis Institute for Medical Research (Mtl)
Quantitative magnetic resonance imaging as a diagnostic tool of intervertebral disc matrix composition and integrity
BROMME, Dieter
University of British Columbia CULLIS, Pieter R $111,844 CIB 3 Yr(s)
Cathepsins K and S inhibition in a rheumatoid arthritis murine model
BULMAN, Dennis E
Ottawa Health Research Institute WALLACE, Valerie A $170,082 G 5 Yr(s)
Identification of a novel gene for brachydactyly-A1
CHEN, Wayne S
University of Calgary $86,495 CBM 3 Yr(s)
Understanding the Molecular Defects and Treatment of Human Malignant Hyperthermia and Central Core Disease
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
56
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Musculoskeletal Health and Arthritis / Appareil locomoteur et arthrite
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
CIBERE, Jolanda
The Arthritis Research Centre of Canada ESDAILE, John M / KOPEC, Jacek A / NICOLAOU, Savvakis / SINGER, Joel / THORNE, Anona E / WONG, Hubert H
 $161,295 PUB 3 Yr(s)
Vancouver Longitudinal Study of Early Knee Osteoarthritis
DE BRUM-FERNANDES, Artur J
Université de Sherbrooke BOIRE, Gilles / PARENT, Jean-Luc
 $92,655 CIB 4 Yr(s)
Anabolic Properties of Prostaglandin D2 in Human Bone
DUTZ, Jan P
University of British Columbia $121,076 CIB 4 Yr(s)
Child and Family Research Institute
Mechanisms of topical TLR activation for the enhancement of immune responses to protein vaccines
EL-GABALAWY, Hani S
University of Manitoba ELIAS, Brenda D / FERUCCI, Elizabeth D / HITCHON, Carol A / OEN, Kiem G / PESCHKEN, Christine A
 $180,148 CIB 5 Yr(s)
Early identification of rheumatoid arthritis in First Nations
FRENETTE, Jérôme
Université Laval $98,013 MOV 4 Yr(s)
Biological integration of tendon healing:new approaches to understand and accelerate tendon repair
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
57
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Musculoskeletal Health and Arthritis / Appareil locomoteur et arthrite
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
GALLOUZI, Imed
McGill University $135,584 MOV 5 Yr(s)
The RNA binding protein HuR is a key player in muscle cell differentiation
HILDEBRAND, Kevin A
University of Calgary HART, David A / SALO, Paul T
 $140,732 CIB 3 Yr(s)
Neuroinflammatory Mechanisms in Joint Contracture Development
HOEMANN, Caroline D
École polytechnique de Montréal EL-GABALAWY, Hani S / RIVARD, Georges E
 $136,497 BME 5 Yr(s)
Defining therapeutic inflammation for articular cartilage regeneration
HOLDSWORTH, David W
University of Western Ontario DUNNING, Cynthia E / NAUDIE, Douglas
 $140,800 MPI 5 Yr(s)
Advanced anatomical and dynamic micro- computed tomography for arthritis research
KAARTINEN, Mari T
McGill University $112,359 CIB 3 Yr(s)
Matrix crosslinking by Factor XIIIA and transglutaminase 2 during bone formation
KOMAROVA, Svetlana V
McGill University $115,842 CIB 5 Yr(s)
Regulation of osteoclast formation and function by cell-cell interactions in the bone microenvironment
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
58
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Musculoskeletal Health and Arthritis / Appareil locomoteur et arthrite
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
LACAILLE, Diane V
The Arthritis Research Centre of Canada ABRAHAMOWICZ, Michal M / ANIS, Aslam H / ESDAILE, John M / TUGWELL, Peter S
 $115,543 HSI 2 Yr(s)
Assessing the quality of care for rheumatoid arthritis at a population level
MCDONALD, Patrick P
Université de Sherbrooke $120,990 CIB 5 Yr(s)
Nuclear signaling in human neutrophils
MOREAU, Robert
Université du Québec à Montréal BRISSETTE, Louise $93,479 CIB 4 Yr(s)
Functions of the scavenger receptors of class B in bone metabolism.
NANCI, Antonio
MOFFATT, Pierre
$110,882 DS 5 Yr(s)
SMITH, Charles E
Université de Montréal
Functional studies and experimental manipulation of ameloblastin expression
OVERALL, Christopher M
University of British Columbia $196,783 DS 5 Yr(s)
Leukocyte Matrix Metalloproteinases (MMPs) in Arthritis
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
59
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Musculoskeletal Health and Arthritis / Appareil locomoteur et arthrite
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
SAVARD, Pierre
École polytechnique de Montréal BUSCHMANN, Michael D / LAVIGNE, Patrick / LI, Leping
 $121,099 BME 4 Yr(s)
Electroarthrography: an original approach for the non-invasive measurement of load-induced electric fields in the knee joint for diagnosis of joint function and joint disease
SIMS, Stephen M
DIXON, S. Jeffrey $162,545 CP 5 Yr(s)
University of Western Ontario
Role of Cytosolic Calcium in the Regulation of Osteoclasts and Bone Resorption
TRIGGS-RAINE, Barbara L
University of Manitoba $151,222 G 5 Yr(s)
Constitutive and regulated pathways of hyaluronan degradation
UNDERHILL, T. Michael
University of British Columbia $139,953 DS 5 Yr(s)
Delineating the Molecular Mechanisms Underlying BMP Action
VACRATSIS, Panayiotis
University of Windsor (Ontario) $81,614 MOV 3 Yr(s)
Molecular mechanisms regulating myotubularin-related lipid phosphatases mutated in neuromuscular diseases
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
60
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Neurosciences, Mental Health and Addiction / Neurosciences, santé mentale et toxicomanies
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
ALDA, Martin
MACQUEEN, Glenda M
$225,467 BSB 5 Yr(s)
ROULEAU, Guy A
TURECKI, Gustavo X
YOUNG, L. T
Dalhousie University (Nova Scotia)
Phenotypic and molecular heterogeneity of bipolar disorder
AMIR, Shimon
Concordia University (Montreal, Quebec) $146,647 BSA 5 Yr(s)
Regulation and function of circadian clocks in the limbic forebrain
AVISON, William R
University of Western Ontario DAVIES, Lorraine E / FORD-GILBOE, Marilyn V / SEALY, Pat / SPEECHLEY, Kathy N
 $144,580 PSB 5 Yr(s)
A Life Course Analysis of Family Structure, Stress, and Mothers' Mental Health: Setting the Stage for a Prospective Study of Families
AVOLI, Massimo
McGill University $102,336 NSA 5 Yr(s)
Montreal Neurological Institute
Cellular mechanisms of epilepsies
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
61
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Neurosciences, Mental Health and Addiction / Neurosciences, santé mentale et toxicomanies
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
BLACK, Sandra E
Sunnybrook Health Sciences Centre CALDWELL, Curtis B / GAO, Fuqiang / HERRMANN, Nathan / KISS, Alexander J / LANCTOT, Krista L / LOBAUGH, Nancy J / MASELLIS, Mario / MCILROY, William E / ROGAEVA, Ekaterina / STEFANOVIC, Bojana / STUSS, Donald T / SWARTZ, Richard
 $282,211 BSB 5 Yr(s)
In Vivo Brain Mapping in the Dementias: A Longitudinal Brain-Behaviour Study With a Focus on interactions of Alzheimer's and Cerebrovascular Disease
BOHBOT, Véronique
Douglas Hospital Research Centre (Verdun, Québec)
 DAGHER, Alain $50,005 BCA 2 Yr(s)
MRI and Virtual Navigational Strategies in Parkinson's Disease
BROWNSTONE, Robert M
Dalhousie University (Nova Scotia) $128,731 MOV 5 Yr(s)
Control of movement: Brain stem control of locomotion
CANTOR, James M
Centre for Addiction and Mental Health (Toronto)
 BARBAREE, Howard E / BLANCHARD, Ray / DICKEY, Robert / GIRARD, Todd A / KLASSEN, Philip E / MIKULIS, David J
 $207,764 BSB 5 Yr(s)
Neuroanatomic features specific to pedophilia
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
62
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Neurosciences, Mental Health and Addiction / Neurosciences, santé mentale et toxicomanies
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
CAYOUETTE, Michel
Institut de recherches cliniques de Montréal $131,595 NSB 3 Yr(s)
Mechanisms of cell-fate choice in the developing mammalian retina
CHAUDHURI, Avi
McGill University $123,156 BSA 3 Yr(s)
Molecular mechanisms of cortical neuroadaptation in primates
CHAUHAN, Balwantray C
Dalhousie University (Nova Scotia) $161,894 CIA 5 Yr(s)
Models of Intraocular Pressure and Endothelin-1 Induced Optic Nerve Damage
CLOUTIER, Jean-Francois
McGill University $154,376 NSB 5 Yr(s)
Montreal Neurological Institute
Molecular mechanisms of sensory systems development
EKKER, Marc
University of Ottawa $176,231 DEV 5 Yr(s)
Regulation and function of Dlx homeobox genes in the developing forebrain of vertebrates.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
63
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Neurosciences, Mental Health and Addiction / Neurosciences, santé mentale et toxicomanies
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
EVERLING, Stefan
University of Western Ontario $167,327 BSC 5 Yr(s)
Robarts Research Institute - U.W.O. (London, Ont.)
Relationship between neural activity and blood oxygenation level-dependent (BOLD) signals in the primate frontal eye fields
FLORES, Cecilia
Douglas Hospital Research Centre (Verdun, Québec)
 $94,239 BSA 3 Yr(s)
Role of netrin-1 in the organization and function of dopamine circuitry
FLORESCO, Stanley B
University of British Columbia $77,204 BSA 5 Yr(s)
Dopaminergic circuits and risky decision making
GALLIN, Warren J
University of Alberta SPENCER, Andrew N $120,477 CP 3 Yr(s)
Structure/function analysis of voltage-gated potassium channels
GUAY, Stéphane
Hôpital Louis H. Lafontaine (Montréal) BOYER, Richard / MARCHAND, André
 $67,273 PSB 5 Yr(s)
Centre de recherche Fernand-Seguin de l'Hôpital Louis H.- Lafontaine (Mtl)
Étude prospective sur l'impact psychologique et social de la victimisation criminelle avec violence
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
64
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Neurosciences, Mental Health and Addiction / Neurosciences, santé mentale et toxicomanies
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
GUITTON, Matthieu J
Université Laval $84,247 BSC 5 Yr(s)
Development of new pharmacological therapeutic strategies for long-term tinnitus.
HENKELMAN, R. Mark
Hospital for Sick Children (Toronto) JOSSELYN, Sheena A / LERCH, Jason P / SLED, John G
 $134,667 MPI 5 Yr(s)
MRI of learning and memory
HESS, Robert F
McGill University $178,994 BSC 5 Yr(s)
The Cortical Sites of Amblyopia and Suppression in Humans
ITIER, Roxane J
Baycrest Centre for Geriatric Care (Toronto) ALAIN, Claude / MCINTOSH, Anthony R
 $67,108 BSC 3 Yr(s)
Modulations of the face and eye gaze processing brain networks
JULIEN, Jean-Pierre
Université Laval $133,300 NSB 5 Yr(s)
Centre hospitalier de l'Université Laval (Québec)
The role of inflammation in pathogenesis and immunotherapy of ALS
KIROUAC, Gilbert J
University of Manitoba $104,691 BSA 5 Yr(s)
Thalamic regulation of the nucleus accumbens
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
65
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Neurosciences, Mental Health and Addiction / Neurosciences, santé mentale et toxicomanies
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
KOZLOWSKI, Piotr
University of British Columbia MACKAY, Alexander L / TETZLAFF, Wolfram G
 $147,458 MPI 3 Yr(s)
Development of MRI techniques for animal models of Spinal Cord Injury
LAMBE, Evelyn K
University of Toronto $143,605 NSA 5 Yr(s)
Cellular and molecular mechanisms underlying development and plasticity of prefrontal attention circuitry
LOMBER, Stephen G
University of Western Ontario $171,162 BSC 5 Yr(s)
Adaptive Cortical Plasticity Following Deafness
LUKOWIAK, Kenneth D
University of Calgary $96,492 BSA 5 Yr(s)
How stress alters memory formation, reconsolidation and forgetting
LYTTON, Jonathan
University of Calgary $175,986 CP 5 Yr(s)
Hippocampal Plasticity: Cellular & Molecular Physiology of the K-Dependent Na/Ca- Exchanger, NCKX2
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
66
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Neurosciences, Mental Health and Addiction / Neurosciences, santé mentale et toxicomanies
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
MA, Weiya
Douglas Hospital Research Centre (Verdun, Québec)
 $94,510 PT 3 Yr(s)
McGill University
Peripherally derived inflammatory mediators and chronic pain
MACDONALD, Scott A
University of Victoria (British Columbia) CALLAGHAN, Russell C / GUIMARAES BORGES, Guilherme L / ROTH, Eric / SALMON, Amy L / STOCKWELL, Tim R / WELLS, Samantha L
 $49,562 PSB 4 Yr(s)
Patterns and consequences of cocaine and alcohol use for substance abuse treatment clients
MEYER, Jeffrey H
Centre for Addiction and Mental Health (Toronto)
 GEORGE, Tony P / HOULE, Sylvain / SELBY, Peter L / WILSON, Alan A
 $143,803 BSB 3 Yr(s)
Cigarette smoking and prefrontal monoamine oxidase-A (MAO-A) binding in health and depression
MILLER, Gregory E
University of British Columbia KOBOR, Michael S / MA, Roy / WROSCH, Carsten
 $189,406 PSB 5 Yr(s)
The Psychobiology of Caregiving for a Spouse with Cancer
MILNER, Theodore E
McGill University $70,372 MOV 2 Yr(s)
Efficacy of robot-assisted rehabilitation of hand function after stroke
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
67
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Neurosciences, Mental Health and Addiction / Neurosciences, santé mentale et toxicomanies
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
MISHARA, Brian L
Université du Québec à Montréal ALDERSON, Marie / CHAGNON, Francois / DAIGLE, Marc S / GREENFIELD, Brian J / HENRY, Melissa / LESAGE, Alain D / RAYMOND, Sylvaine / SOARES, Angelo / ST- LAURENT, Danielle / TOUSIGNANT, Michel
 $98,788 PSB 3 Yr(s)
Suicide, santé mentale et milieu de travail: Étude des conséquences du suicide d'un travailleur sur la santé mentale des collègues et sur le climat de travail
MÜLLER, Daniel J
Centre for Addiction and Mental Health (Toronto)
 COHN, Tony A / KENNEDY, James L / REMINGTON, Gary / TIWARI, Arun K
 $161,486 BSB 5 Yr(s)
Genetics of Antipsychotic-Induced Metabolic Syndrome
NGAN, Elton T
University of British Columbia WOODWARD, Todd S $54,942 BSB 4 Yr(s)
University Hospital (U.B.C.)
Physiological and behavioral evidence of conflict modulation failure in dual stream information processing in delusional schizophrenic patients.
NICOLSON, Robert J
London Health Sciences Centre Res. Inc. (Ont.)
 DROST, Dick J / GELMAN, Neil / NEUFELD, Richard W / THEBERGE, Jean / WILLIAMSON, Peter C
 $127,989 BSB 3 Yr(s)
Neurobiological Markers of Aberrant Connectivity in Autism
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
68
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Neurosciences, Mental Health and Addiction / Neurosciences, santé mentale et toxicomanies
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
OBERLANDER, Timothy F
University of British Columbia BOYCE, Thomas W / BRANT, Rollin F / DEVLIN, Angela M / DIAMOND, Adele / GRUNAU, Ruth E / MISRI, Shaila / WEINBERG, Joanne / YOUNG, Allan H
 $122,094 CHI 5 Yr(s)
Executive Functions and stress reactivity in 5- 7 year olds following prenatal serotonin reuptake inhibitor exposure
PARKINSON, Fiona E
ALBENSI, Benedict C ANDERSON, Christopher M
 $119,841 PT 5 Yr(s)
University of Manitoba
Regulation of brain adenosine levels by ecto- enzymes and membrane transporters.
PATTEN, Scott B
University of Calgary ELIASZIW, Michael / MARRA, Carlo A
 $70,003 PSB 3 Yr(s)
Major Depression and Health Status Changes
PETERS, Terence M
University of Western Ontario LEE, Donald H / MIRSATTARI, Seyed M / PARRENT, Andrew G
 $141,416 MPI 5 Yr(s)
Image-guided surgery for epilepsy
PETRONIS, Arturas
Centre for Addiction and Mental Health (Toronto)
 $293,530 BSB 3 Yr(s)
Epigenomics of Schizophrenia
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
69
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Neurosciences, Mental Health and Addiction / Neurosciences, santé mentale et toxicomanies
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
PITTMAN, Quentin J
University of Calgary $126,497 NSA 5 Yr(s)
Plasticity of neuroendocrine and autonomic synapses
PRAT, Alexandre
Centre Hosp. de l'Université de Montréal (CHUM)
 ARBOUR, Nathalie $110,940 NSB 5 Yr(s)
Novel Adhesion Molecules of the Blood-Brain Barrier Regulating CNS Inflammation
PROCHAZKA, Arthur
University of Alberta $113,901 BME 5 Yr(s)
Restoration of upper extremity function with a novel implanted neuroprosthesis.
RICHARD, Denis
Université Laval $92,437 M 5 Yr(s)
Institut universitaire de cardiologie et pneumologie de Québec
The Role of the Melanin-Concentrating Hormone System in the Regulation of Energy Balance
ROSKAMS, Angela J
University of British Columbia $151,033 CBM 5 Yr(s)
Regulation of Brain Lipid Binding Protein in Growth-Promoting Glia
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
70
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Neurosciences, Mental Health and Addiction / Neurosciences, santé mentale et toxicomanies
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
ROSKAMS, Angela J
University of British Columbia $148,178 NSB 5 Yr(s)
A role for SPARC in the Regulation of CNS Repair
ROSSIGNOL, Serge
Université de Montréal $174,786 MOV 5 Yr(s)
Adaptive mechanisms of spinal locomotion
ROUCOU, Xavier
Université de Sherbrooke $141,210 CBM 5 Yr(s)
Molecular activity of prion protein oligomers in health and diseases
ROUILLARD, Claude
LEVESQUE, Daniel
MARTINOLI, Maria- Grazia
 $145,864 BSA 5 Yr(s)
Université Laval
Centre hospitalier de l'Université Laval (Québec)
Nuclear receptors and dopamine neurotransmission: A yin-yang relationship
ROULEAU, Guy A
Centre Hosp. de l'Université de Montréal (CHUM)
 JULIEN, Jean-Pierre / PARKER, Jodey A / VANDE VELDE, Christine Diane C
 $169,522 NSA 5 Yr(s)
Cellular and biochemical impact of TDP-43 mutants in ALS
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
71
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Neurosciences, Mental Health and Addiction / Neurosciences, santé mentale et toxicomanies
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
SAREEN, Jitender
University of Manitoba ASMUNDSON, Gordon J / COX, Brian J / WANG, Jianli
 $60,000 PSB 2 Yr(s)
Work Stress and Childhood Adversity in relation to Mental Disorders and Suicidality Among Canadian Soldiers: Analysis of a large Population-Based Sample
SCHILLER, Peter W
Institut de recherches cliniques de Montréal $135,814 PS 5 Yr(s)
Neuropeptides and peptidomimetics as parmacological tools and potential drugs
SCHUURMANS, Carol J
University of Calgary $135,115 DEV 5 Yr(s)
Molecular regulation of layer formation in the developing CNS
SHOICHET, Molly S
University of Toronto TATOR, Charles H $129,011 BME 4 Yr(s)
Minimally-invasive Drug Delivery Strategy for Acute Spinal Cord Injury Repair
SINGH, Shiva M
O'REILLY, Richard L $183,166 BSB 3 Yr(s)
SCHERER, Stephen W
University of Western Ontario
Gene discovery in schizophrenia using copy number variations (CNVs) in high-risk monozygotic (MZ) and dizygotic (DZ) twins
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
72
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Neurosciences, Mental Health and Addiction / Neurosciences, santé mentale et toxicomanies
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
SOJA, Peter J
University of British Columbia $122,952 BSC 5 Yr(s)
Sensory Inflow Through the Spinothalamic Tract During Normal vs. Restricted Sleep
SONG, Cai
University of Prince Edward Island (Charlottetown)
 $91,333 BSA 3 Yr(s)
Interleukin-1beta, neurodegeneration, and memory impairment: an insight into imbalances between pro- and anti- inflammation, and between neurotoxicity and neuroprotection
STELLWAGEN, David
The Research Institute of the McGill University Health Centre
 $147,738 NSB 5 Yr(s)
The role of TNFalpha in synaptic plasticity and during neurodegeneration
STIFANI, Stefano
McGill University $154,750 NSA 5 Yr(s)
Basal Telencephalic Limbic System Development
STRONG, Michael J
University of Western Ontario $171,530 NSA 3 Yr(s)
Robarts Research Institute - U.W.O. (London, Ont.)
The role of TDP-43 in regulating NFL mRNA metabolism.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
73
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Neurosciences, Mental Health and Addiction / Neurosciences, santé mentale et toxicomanies
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
SZATMARI, Peter
McMaster University BRYSON, Susan E / FERNANDEZ, Bridget A / GOLDBERG, Jeremy / MAHONEY, William J / PATERSON, Andrew D / ROBERTS, Sheila (Wendy) G / SCHERER, Stephen W / TUFF, Lawrence / VINCENT, John B / ZWAIGENBAUM, Lonnie
 $155,946 BSB 5 Yr(s)
The Genetic Epidemiology of Autism; Family and Molecular Studies
THOMPSON, Roger J
University of Calgary $117,436 NSB 5 Yr(s)
Pannexin-1 Hemichannel Activation in Neurons.
TSUI, Ban C
University of Alberta $49,489 CIA 3 Yr(s)
Electrical impedance: a novel approach for detecting intraneural needle placement in regional anesthesia.
TYMIANSKI, Michael
University Health Network (Toronto) $179,793 NSB 5 Yr(s)
Toronto Western Hospital
Role of TRPM Channels in Ischemic Brain Damage
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
74
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Neurosciences, Mental Health and Addiction / Neurosciences, santé mentale et toxicomanies
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
WANG, Jianli
University of Calgary CURRIE, Shawn R / PATTEN, Scott B / SAREEN, Jitender / SCHMITZ, Norbert
 $63,345 POP 3 Yr(s)
Perceived needs and utilization of workplace mental health accommodations among workers with depressive and anxiety disorders
WANG, Lu-Yang
Hospital for Sick Children (Toronto) $157,229 NSA 5 Yr(s)
Spatial and temporal plasticity of neurotransmitter release at a developing central synapse
WANG, Yu Tian
University of British Columbia $204,293 NSB 5 Yr(s)
Regulation of postsynaptic expression and function of GABA-A receptors
WINSTANLEY, Catharine A
University of British Columbia $126,693 BSA 5 Yr(s)
Determining the effects of monoaminergic regulation of frontostriatal systems in different aspects of impulsive decision-making.
WONG, Agnes
Hospital for Sick Children (Toronto) GOLTZ, Herbert C / MIRABELLA, Giuseppe
 $95,673 CIA 5 Yr(s)
Timing of Surgery for Crossed Eyes in Infancy: A Clinical Evaluation of Sensory and Motor Outcomes
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
75
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Neurosciences, Mental Health and Addiction / Neurosciences, santé mentale et toxicomanies
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
WONG-WYLIE, Douglas R
University of Alberta $60,000 BSC 3 Yr(s)
Physiological, Anatomical and Molecular Organization of the Cerebellum
WOODWARD, Todd S
University of British Columbia HONER, William G / MORITZ, Steffen / NGAN, Elton T
 $99,608 BSB 4 Yr(s)
Integration of Disconfirmatory Evidence in Schizophrenia: Cognitive and Neural Underpinnings
ZATORRE, Robert J
McGill University SCHONWIESNER, Marc $159,057 BSC 5 Yr(s)
Montreal Neurological Institute
Mapping the human auditory cortex: low-level features and higher-order interactions
ZOCHODNE, Douglas W
University of Calgary $111,945 NSA 5 Yr(s)
Diabetes, neuron degeneration and insulin signaling
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
76
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Nutrition, Metabolism and Diabetes / Nutrition, métabolisme et diabète
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
ALLARD, Johane P
University Health Network (Toronto) GUINDI, Maha / MA, David W / MCGILVRAY, Ian D / THERAPONDOS, George
 $118,261 NUT 3 Yr(s)
Non-alcoholic fatty liver disease: Role of fatty acid composition and gene expression
BARACOS, Vickie E
University of Alberta DIELEMAN, Levinus A / FIELD, Catherine J / SAWYER, Michael B
 $104,791 NUT 3 Yr(s)
Nutritional modulation of antineoplastic therapy
BURT, Helen M
University of British Columbia BALLY, Marcel B / WATERHOUSE, Dawn N
 $126,909 PS 4 Yr(s)
Inhibition of drug efflux transport proteins by amphiphilic diblock copolymers
DAVISON, Sara
University of Alberta KLARENBACH, Scott / TONELLI, Marcello A
 $79,676 PLC 4 Yr(s)
Characterizing the Dying Experience and End- of-Life Care Needs for Patients with Chronic Kidney Disease
EL-SOHEMY, Ahmed
University of Toronto $60,000 NUT 3 Yr(s)
Genetic modifiers of coffee intake on cardiovascular disease risk
GAISANO, Herbert Y
University of Toronto OSBORNE, Lucy R $120,271 M 5 Yr(s)
Distinct insulin exocytotic actions of Syntaxins-1 and -2
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
77
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Nutrition, Metabolism and Diabetes / Nutrition, métabolisme et diabète
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
GIACCA, Adria
University of Toronto $122,408 M 5 Yr(s)
Mechanisms of fat-induced hepatic insulin resistance in vivo
GOUGEON, Réjeanne D
McGill University MARLISS, Errol B / MORAIS, José A
 $164,736 NUT 5 Yr(s)
Royal Victoria Hospital (Montreal)
Insulin sensitivity of protein in Type 2 Diabetes Mellitus
HEATHCOTE, Elizabeth Jane J
University Health Network (Toronto) SIMINOVITCH, Katherine A
 $245,508 EM 3 Yr(s)
Toronto Western Hospital
Molecular Dissection of Primary Biliary Cirrhosis
HEBERT, Marie-Josée
Centre Hosp. de l'Université de Montréal (CHUM)
 BENDAYAN, Moise $116,202 EM 3 Yr(s)
Characterization of non-classical protein secretion pathways of importance in the fibrogenic paracrine response triggered by apoptosis
HUFF, Murray W
University of Western Ontario $135,198 M 4 Yr(s)
Robarts Research Institute - U.W.O. (London, Ont.)
Regulation of Foam Cell Formation: Relationship to Atherosclerosis
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
78
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Nutrition, Metabolism and Diabetes / Nutrition, métabolisme et diabète
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
ISENRING, Paul
Université Laval $137,063 CSA 5 Yr(s)
Hôtel-Dieu de Québec
Molecular mechanisms underlying the normal operation and the physiological role of the renal Na-K-Cl cotransporter splice variants.
JIN, Tianru
University Health Network (Toronto) $112,724 M 5 Yr(s)
Mechanisms underlying the production and homeostasis of the incretin hormone GLP-1
JOHNSON, Jeffrey A
MARRA, Carlo A VEUGELERS, Paul J / YASUI, Yutaka
 $68,755 HSI 2 Yr(s)
University of Alberta
Cancer incidence for patients with Type 2 Diabetes exposed to oral hypoglycemics: Are there differences between agents?
KEITH, Mary E
St. Michael's Hospital (Toronto) LEONG-POI, Howard M / STEWART, Duncan J
 $118,783 NUT 3 Yr(s)
Defining the effects of B vitamins on the endogenous angiogenic response to ischemia
KIM, Richard B
University of Western Ontario DRESSER, George K / TIRONA, Rommel G
 $159,771 PS 5 Yr(s)
Hepatic Organic Anion Transporting Polypeptide (OATP) drug uptake transporters as determinants of drug disposition
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
79
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Nutrition, Metabolism and Diabetes / Nutrition, métabolisme et diabète
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
KISS, Robert S
The Research Institute of the McGill University Health Centre
 YAO, Zemin $105,629 M 3 Yr(s)
Understanding of regulated intracellular cholesterol movement and cell growth through interplay between LRP1 and its adapter proteins
LABRIE, Claude
Université Laval $138,651 E 5 Yr(s)
Centre hospitalier de l'Université Laval (Québec)
Molecular mechanism of action of the membrane-bound transcription factor AIbZIP
MA, David W
University of Guelph $108,619 NUT 3 Yr(s)
Role of caveolae and fatty acids in pubertal mammary gland development and carcinogenesis
MCGRATH, Jennifer J
Concordia University (Montreal, Quebec) BROUILLETTE, Robert / CHAPUT, Jean-Philippe / CONSTANTIN, Evelyn / JARRIN, Denise C / KLINE, Rex B / LAMBERT, Marie / PARADIS, Gilles / POIRIER, Paul / TREMBLAY, Angelo
 $270,745 CHI 5 Yr(s)
Sleep and Obesity in Children and Adolescents: Identifying Pathogenic Pathways
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
80
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Nutrition, Metabolism and Diabetes / Nutrition, métabolisme et diabète
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
MITCHINSON, Wendy L
University of Waterloo (Ontario) $55,368 ELH 3 Yr(s)
History of Obesity in Canada, 1920-1980
PUNTHAKEE, Zubin
DEVEREAUX, Philip J HILL, Stephen A / MCQUEEN, Matthew J
 $71,118 POP 3 Yr(s)
GERSTEIN, Hertzel C
McMaster University
Glucose as a predictor of Vascular events In noncardiac Surgery patIents cOhort evaluatioN (GlucoVISION)
ROZAKIS ADCOCK, Maria
University of Toronto WHEELER, Michael B $79,765 M 3 Yr(s)
Role of PHIP in Beta Cell Function
ROZEN, Rima
The Research Institute of the McGill University Health Centre
 $137,067 NUT 5 Yr(s)
Low dietary folate and colorectal carcinogenesis
VANCE, Dennis E
University of Alberta $167,668 M 5 Yr(s)
Phosphatidylcholine metabolism and obesity
WALLACE, John L
University of Calgary $158,609 EM 5 Yr(s)
NSAID Gastropathy and Cytoprotection
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
81
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Nutrition, Metabolism and Diabetes / Nutrition, métabolisme et diabète
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
WANG, Rennian
University of Western Ontario $131,229 M 3 Yr(s)
Determination of the Mechanisms by which the c-Kit Tyrosine Kinase Receptor Regulates Pancreatic Beta Cell Development, Function and Survival.
WARD, Wendy E
University of Toronto $93,771 NUT 3 Yr(s)
Neonatal isoflavone exposure and long term programming of bone metabolism
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
82
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Population and Public Health / Santé publique et des populations
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
DENDUKURI, Nandini
PAI, Madhukar
$60,992 PUB 3 Yr(s)
McGill University
Novel statistical methods for Tuberculosis diagnostic studies
DOSMAN, James A
GORDON, John R CHEN, Yue / PITBLADO, John R / RENNIE, Donna Carole
 $283,785 POP 6 Yr(s)
PAHWA, Punam
University of Saskatchewan
Saskatchewan Rural Health Study
ERNST, Pierre-Paul
McGill University BRASSARD, Paul / DELANEY, Joseph Austin C / MIKAELOFF, Yann / SUISSA, Samy
 $71,327 PUB 2 Yr(s)
Adverse effects of inhaled corticosteroids in patients with respiratory disease.
GOLDBERG, Mark S
KHAIRY, Paul
BROPHY, James M / BURNETT, Richard T / ESSEBAG, Vidal / HADJIS, Tom A / MAYO, Nancy E / MILLER, Sydney B / TALAJIC, Mario
 $178,922 POP 5 Yr(s)
McGill University
The Research Institute of the McGill University Health Centre
A longitudinal study to identify factors that trigger ventricular tachyarrythmias among persons with implanted cardioverter defibrillators
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
83
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Population and Public Health / Santé publique et des populations
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
KAPLAN, Gilaad G
VILLENEUVE, Paul J
HILSDEN, Robert J / NGUYEN, Geoffrey C / WHEELER, Amanda J
 $96,696 PUB 2 Yr(s)
University of Calgary
The effect of outdoor air pollution on the incidence and prognosis of the inflammatory bowel diseases in Canada
LOUCKS, Eric B
Douglas Hospital Research Centre (Verdun, Québec)
 ABRAHAMOWICZ, Michal M / ENGERT, James C / HARPER, Samuel / LYNCH, John W / MEANEY, Michael J / PILOTE, Louise
 $62,622 PUB 3 Yr(s)
Life Course Socioeconomic Position, Type II Diabetes, and Obesity: Potential Interactions with Genetic Polymorphisms
MCINTYRE, Lynn
University of Calgary CURTIS, Lori J / EMERY, John H / KIRKPATRICK, Sharon / MCLAREN, Lindsay / TARASUK, Valerie S / WOLFSON, Michael C
 $124,290 POP 3 Yr(s)
Policy Drivers of Food Insecurity in Canada, 1994-2006
OKEY, Allan B
University of Toronto BOUTROS, Paul C $131,064 PT 3 Yr(s)
Dioxin toxicity: gene expression in a resistant rat model
PAI, Madhukar
The Research Institute of the McGill University Health Centre
 DALEY, Peter / DENDUKURI, Nandini / DHEDA, Keertan / GREENAWAY, Christina A / MENZIES, Richard
 $100,626 PUB 3 Yr(s)
Innovative approaches for diagnosing tuberculosis in the era of HIV
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
84
Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Primary Institute : Population and Public Health / Santé publique et des populations
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual
Operating Amount
 Equipment PRC** Term Status
PANG, Kim-Ching S
University of Toronto $120,717 PS 5 Yr(s)
Interplay of Transporters, Enzymes, and Nuclear Receptors in First-Pass Drug Absorption
YUSUF, Salim
CHOW, Clara K
GILMORE, Anna B / MCKEE, Martin / POGUE, Janice M / SANKARANARAYANA N, Subramanian V / TEO, Koon K
 $143,385 POP 2 Yr(s)
McMaster University
Upstream Determinants of Smoking in Low, Middle and High Income Countries participating in PURE (Prospective Urban Rural Epidemiologic study)
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
85
Peer Review Committees
PRC Name
ABH Aboriginal Peoples' Health
BCA Biological and Clinical Aspects of Aging
BMA Biochemistry & Molecular Biology - A
BMB Biochemistry & Molecular Biology - B
BME Biomedical Engineering
BSA Behavioural Sciences - A
BSB Behavioural Sciences - B
BSC Behavioural Sciences - C
CBM Cell Biology & Mechanisms of Disease
CBT Cancer Biology & Therapeutics
CHI Children's Health
CIA Clinical Investigation - A
CIB Clinical Investigation - B
CP Cell Physiology
CPT Cancer Progression & Therapeutics
CSA Cardiovascular System - A
CSB Cardiovascular System - B
CSC Cardiovascular System - C
DEV Developmental Biology
DS Dental Sciences
E Endocrinology
ELH Health Ethics, Law & Humanities
EM Experimental Medicine
G Genetics
GMX Genomics
GSH Gender, Sex & Health
HPM Health Policy & Systems Management Research
HSI Health Services Evaluation and Interventions Research - B
HSR Health Services Evaluation & Interventions Research - A
IT Immunology and Transplantation
KTE Knowledge Translation & Exchange
M Metabolism
MCC Molecular & Cellular Biology of Cancer
MI Microbiology & Infectious Diseases
MOV Movement & Exercise
MPI Medical Physics & Imaging
NSA Neurosciences - A
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
86
Peer Review Committees
PRC Name
NSB Neurosciences - B
NUT Nutrition, Food & Health
PLC Palliative & End of Life Care
POP Public, Community & Population Health - A