Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated: 18/03/2009
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
ABH PATERSON, Barbara L LEBLANC, Denis / LOPPIE READING, Charlotte J / MOORE, Carla S / WIEN, Frederic C
 $102,347 2 Yr(s)
University of New Brunswick (Fredericton)
"Talking with their feet": Origins and impact of and potential solutions to non-attendance in diabetes clinics by Aboriginal people
ABH SMITH, Dawn A ANDREW, Caroline P / EDWARDS, Nancy C / PETERSON, Wendy
 $65,682 2 Yr(s)
University of Ottawa
Improving access to preventive early childhood services for urban Aboriginal families: A participatory research study
BCA BOHBOT, Véronique DAGHER, Alain $50,005 2 Yr(s)
Douglas Hospital Research Centre (Verdun, Québec)
MRI and Virtual Navigational Strategies in Parkinson's Disease
BCA HARKNESS, Troy A $86,692 3 Yr(s)
University of Saskatchewan
Mechanisms facilitating Anaphase Promoting Complex-dependent lifespan in yeast
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
1
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
BCA HOOD, David A $105,687 4 Yr(s)
York University (Toronto, Ontario)
Mitochondria in aging skeletal muscle
BCA KHALIL, Abdelouahed CUNNANE, Stephen / GRENIER, Guillaume
 $105,131 4 Yr(s)
Université de Sherbrooke
Centre de recherche sur le vieillissement (QC)
Mécanismes d'action des paraoxonases 1 et 3 dans la régulation des propriétés anti- athérogènes des HDL au cours du vieillissement
BCA MCELHANEY, Janet E KOLLMANN, Tobias R / MENEILLY, Graydon S
 $128,802 3 Yr(s)
University of British Columbia
Vancouver Coastal Health Research Institute
Inflammaging, Diabetes & Metabolic Sydrome: Effect on T-Cell Responses to Influenza
BCA PAUDEL, Hemant K $134,809 3 Yr(s)
Jewish General Hospital (Montreal)
Tau protein and Alzheimer's disease
BCA PRADO, Vania F
PRADO, Marco A $164,525 5 Yr(s)
University of Western Ontario
The role of basal forebrain cholinergic neurons in synaptic plasticity and cognition.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
2
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
BCA RAJAH, Maria N GRADY, Cheryl L / PRUESSNER, Jens C
 $86,882 3 Yr(s)
Douglas Hospital Research Centre (Verdun, Québec)
Dissociating regional changes in prefrontal cortex structure and function that impact memory performance during normal aging
BCA SHERWIN, Barbara B $70,089 4 Yr(s)
McGill University
Estrogen and Cognitive Aging in Women: A Test of the Critical Period Hypothesis
BCA SINAL, Christopher J
$138,982 3 Yr(s)
Dalhousie University (Nova Scotia)
Chemerin/CMKLR1: A Molecular Switch to Regulate Bone Marrow Adipogenesis and Osteoblastogenesis
BCA TANNENBAUM, Cara
BELLEVILLE, Sylvie N / MULSANT, Benoit H
 $129,482 5 Yr(s)
Institut universitaire de gériatrie de Montréal
Querying cognition and pharmacologic treatment of urinary incontinence in the elderly
BCA WELLINGTON, Cheryl L DONKIN, James / FAN, Jianjia
 $187,482 5 Yr(s)
University of British Columbia
Child and Family Research Institute
The role of ABCA1 and apolipoprotein E in brain lipid metabolism and amyloidogenesis
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
3
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
BMA BORASTON, Alisdair B SMITH, Steven P $169,977 5 Yr(s)
University of Victoria (British Columbia)
Carbohydrate-recognition in bacterial pathogenesis: structural and functional analysis of virulence-associated Clostridium perfringens enzymes.
BMA CYGLER, Mirek M MATTE, Allan M / VALVANO, Miguel A
 $202,526 5 Yr(s)
McGill University
Structure-Function Relationships of Bacterial Polysaccharide Co-Polymerases
BMA DUNN, Stanley D $140,014 5 Yr(s)
University of Western Ontario
Energy Coupling in ATP Synthase
BMA EVANS, Stephen V
$123,281 5 Yr(s)
University of Victoria (British Columbia)
Structure-function studies of glycosyltransferases
BMA GLOVER, John Newman M $154,097 5 Yr(s)
University of Alberta
Regulation of Bacterial Conjugation
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
4
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
BMA JIA, Zongchao $160,565 5 Yr(s)
Queen's University (Kingston, Ontario)
EF-hand proteins and calcium-mediated modulation
BMA JUNOP, Murray S $130,841 5 Yr(s)
McMaster University
Unraveling the Molecular Mechanisms of Non- homologous DNA End-joining
BMA NG, Kenneth K
$111,416 4 Yr(s)
University of Calgary
Molecular structural basis of replication in medically important caliciviruses and flaviviruses
BMA PAETZEL, Mark W
$156,468 5 Yr(s)
Simon Fraser University (Burnaby, B.C.)
Structural analysis of the molecular machinery involved in protein secretion and membrane protein assembly.
BMA WEINER, Joel H $114,626 5 Yr(s)
University of Alberta
Bacterial complex II homologs as models for mitochondrial electron transfer
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
5
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
BMB CHTEINBERG, Serguei V $108,876 5 Yr(s)
Université de Montréal
Exploring the mechanisms of alternative reading of genetic code
BMB DAVIE, James R $159,827 5 Yr(s)
University of Manitoba
Histone modifications and the epigenetic state of transcribed chromatin
BMB HOLCIK, Martin
$136,392 3 Yr(s)
Children's Hospital of Eastern Ontario (Ottawa)
Regulation of internal initiation of translation in cell death and survival
BMB MENEGHINI, Marc D $150,524 5 Yr(s)
University of Toronto
Functional analysis of a developmentally regulated Jumonji-family histone demethylation pathway in Saccharomyces cerevisiae.
BMB NODWELL, Justin R $144,910 5 Yr(s)
McMaster University
Links between antibiotic production and resistance in producer organisms
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
6
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
BMB VERREAULT, Alain $138,426 5 Yr(s)
Université de Montréal
Chromatin Assembly during DNA Replication
BME HOEMANN, Caroline D EL-GABALAWY, Hani S / RIVARD, Georges E
 $136,497 5 Yr(s)
École polytechnique de Montréal
Defining therapeutic inflammation for articular cartilage regeneration
BME MACAULAY, Calum E LANE, Pierre / POH, Catherine / ROSIN, Miriam P
 $87,394 3 Yr(s)
University of British Columbia
B.C. Cancer Research Centre (Vancouver)
Development and evaluation of in vivo confocal imaging of the oral mucosa: Applications in oral cancer screening, diagnosis and surveillance
BME PROCHAZKA, Arthur $113,901 5 Yr(s)
University of Alberta
Restoration of upper extremity function with a novel implanted neuroprosthesis.
BME RUEL, Marc DE KEMP, Robert A / GRIFFITH, May C / STEWART, Duncan J / WHITMAN, Stewart C
 $149,827 4 Yr(s)
SUURONEN, Erik
University of Ottawa
University of Ottawa Heart Institute
Mechanisms of Progenitor Cell-based Angiogenic Therapy with Tissue-Engineered Biopolymer Delivery Matrices and Effects of Host Substrate Modification
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
7
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
BME SAVARD, Pierre BUSCHMANN, Michael D / LAVIGNE, Patrick / LI, Leping
 $121,099 4 Yr(s)
École polytechnique de Montréal
Electroarthrography: an original approach for the non-invasive measurement of load-induced electric fields in the knee joint for diagnosis of joint function and joint disease
BME SEFTON, Michael V WOODHOUSE, Kimberly A $94,540 3 Yr(s)
University of Toronto
Modular Tissue Engineering
BME SHOICHET, Molly S TATOR, Charles H $129,011 4 Yr(s)
University of Toronto
Minimally-invasive Drug Delivery Strategy for Acute Spinal Cord Injury Repair
BME TRUONG, Kien K
$66,437 3 Yr(s)
University of Toronto
Live cell imaging of caspase specific kinetics using fluorescent protein biosensors
BSA AMIR, Shimon $146,647 5 Yr(s)
Concordia University (Montreal, Quebec)
Regulation and function of circadian clocks in the limbic forebrain
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
8
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
BSA CHAUDHURI, Avi $123,156 3 Yr(s)
McGill University
Molecular mechanisms of cortical neuroadaptation in primates
BSA FLORES, Cecilia $94,239 3 Yr(s)
Douglas Hospital Research Centre (Verdun, Québec)
Role of netrin-1 in the organization and function of dopamine circuitry
BSA FLORESCO, Stanley B $77,204 5 Yr(s)
University of British Columbia
Dopaminergic circuits and risky decision making
KIROUAC, Gilbert J
BSA $104,691 5 Yr(s)
University of Manitoba
Thalamic regulation of the nucleus accumbens
BSA LUKOWIAK, Kenneth D $96,492 5 Yr(s)
University of Calgary
How stress alters memory formation, reconsolidation and forgetting
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
9
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
BSA ROUILLARD, Claude MARTINOLI, Maria-Grazia $145,864 5 Yr(s)
LEVESQUE, Daniel
Université Laval
Centre hospitalier de l'Université Laval (Québec)
Nuclear receptors and dopamine neurotransmission: A yin-yang relationship
BSA SONG, Cai
$91,333 3 Yr(s)
University of Prince Edward Island (Charlottetown)
Interleukin-1beta, neurodegeneration, and memory impairment: an insight into imbalances between pro- and anti-inflammation, and between neurotoxicity and neuroprotection
BSA VIAU, Victor
$153,421 5 Yr(s)
University of British Columbia
Androgen sensitive pathways to the paraventricular nucleus of the hypothalamus
BSA WINSTANLEY, Catharine A $126,693 5 Yr(s)
University of British Columbia
Determining the effects of monoaminergic regulation of frontostriatal systems in different aspects of impulsive decision-making.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
10
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
BSB ALDA, Martin $225,467 5 Yr(s)
MACQUEEN, Glenda M
ROULEAU, Guy A
TURECKI, Gustavo X
YOUNG, L. T
Dalhousie University (Nova Scotia)
Phenotypic and molecular heterogeneity of bipolar disorder
BSB BARR, Cathy L
KERR, Elizabeth N / LOVETT, Maureen W
 $200,665 5 Yr(s)
University Health Network (Toronto)
Toronto Western Research Institute (Toronto)
Genetics of Reading Disabilities
BSB BLACK, Sandra E CALDWELL, Curtis B / GAO, Fuqiang / HERRMANN, Nathan / KISS, Alexander J / LANCTOT, Krista L / LOBAUGH, Nancy J / MASELLIS, Mario / MCILROY, William E / ROGAEVA, Ekaterina / STEFANOVIC, Bojana / STUSS, Donald T / SWARTZ, Richard
 $282,211 5 Yr(s)
Sunnybrook Health Sciences Centre
In Vivo Brain Mapping in the Dementias: A Longitudinal Brain-Behaviour Study With a Focus on interactions of Alzheimer's and Cerebrovascular Disease
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
11
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
BSB CANTOR, James M BARBAREE, Howard E / BLANCHARD, Ray / DICKEY, Robert / GIRARD, Todd A / KLASSEN, Philip E / MIKULIS, David J
 $207,764 5 Yr(s)
Centre for Addiction and Mental Health (Toronto)
Neuroanatomic features specific to pedophilia
BSB CHERTKOW, Howard M EVANS, Alan C / THIEL, Alexander / WHATMOUGH, Christine E
 $149,843 3 Yr(s)
Jewish General Hospital (Montreal)
Lady Davis Institute for Medical Research (Mtl)
Diagnosis, localization, and treatment of semantic memory impairment in Alzheimer's Disease
BSB MEYER, Jeffrey H GEORGE, Tony P / HOULE, Sylvain / SELBY, Peter L / WILSON, Alan A
 $143,803 3 Yr(s)
Centre for Addiction and Mental Health (Toronto)
Cigarette smoking and prefrontal monoamine oxidase-A (MAO-A) binding in health and depression
BSB MÜLLER, Daniel J COHN, Tony A / KENNEDY, James L / REMINGTON, Gary / TIWARI, Arun K
 $161,486 5 Yr(s)
Centre for Addiction and Mental Health (Toronto)
Genetics of Antipsychotic-Induced Metabolic Syndrome
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
12
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
BSB NGAN, Elton T WOODWARD, Todd S $54,942 4 Yr(s)
University of British Columbia
University Hospital (U.B.C.)
Physiological and behavioral evidence of conflict modulation failure in dual stream information processing in delusional schizophrenic patients.
BSB NICOLSON, Robert J
DROST, Dick J / GELMAN, Neil / NEUFELD, Richard W / THEBERGE, Jean / WILLIAMSON, Peter C
 $127,989 3 Yr(s)
London Health Sciences Centre Res. Inc. (Ont.)
Neurobiological Markers of Aberrant Connectivity in Autism
BSB PETRONIS, Arturas $293,530 3 Yr(s)
Centre for Addiction and Mental Health (Toronto)
Epigenomics of Schizophrenia
BSB SINGH, Shiva M $183,166 3 Yr(s)
O'REILLY, Richard L
SCHERER, Stephen W
University of Western Ontario
Gene discovery in schizophrenia using copy number variations (CNVs) in high-risk monozygotic (MZ) and dizygotic (DZ) twins
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
13
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
BSB SZATMARI, Peter BRYSON, Susan E / FERNANDEZ, Bridget A / GOLDBERG, Jeremy / MAHONEY, William J / PATERSON, Andrew D / ROBERTS, Sheila (Wendy) G / SCHERER, Stephen W / TUFF, Lawrence / VINCENT, John B / ZWAIGENBAUM, Lonnie
 $155,946 5 Yr(s)
McMaster University
The Genetic Epidemiology of Autism; Family and Molecular Studies
BSB WOODWARD, Todd S HONER, William G / MORITZ, Steffen / NGAN, Elton T
 $99,608 4 Yr(s)
University of British Columbia
Integration of Disconfirmatory Evidence in Schizophrenia: Cognitive and Neural Underpinnings
BSB YU, Dickie C MARTIN, Garry L $73,509 3 Yr(s)
University of Manitoba
Improving the quality of life for people with severe and profound intellectual disabilities: Studies of choice making
BSC EVERLING, Stefan $167,327 5 Yr(s)
University of Western Ontario
Robarts Research Institute - U.W.O. (London, Ont.)
Relationship between neural activity and blood oxygenation level-dependent (BOLD) signals in the primate frontal eye fields
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
14
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
BSC GUITTON, Matthieu J $84,247 5 Yr(s)
Université Laval
Development of new pharmacological therapeutic strategies for long-term tinnitus.
BSC HASHER, Lynn GRADY, Cheryl L $98,511 3 Yr(s)
Baycrest Centre for Geriatric Care (Toronto)
Rotman Research Institute (Toronto, Ontario)
Aging and Memory: Behavoural and Neural Underpinnings of Memory Failure
BSC HESS, Robert F $178,994 5 Yr(s)
McGill University
The Cortical Sites of Amblyopia and Suppression in Humans
BSC ITIER, Roxane J ALAIN, Claude / MCINTOSH, Anthony R
 $67,108 3 Yr(s)
Baycrest Centre for Geriatric Care (Toronto)
Modulations of the face and eye gaze processing brain networks
BSC LOMBER, Stephen G $171,162 5 Yr(s)
University of Western Ontario
Adaptive Cortical Plasticity Following Deafness
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
15
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
BSC SOJA, Peter J $122,952 5 Yr(s)
University of British Columbia
Sensory Inflow Through the Spinothalamic Tract During Normal vs. Restricted Sleep
BSC WONG-WYLIE, Douglas R $60,000 3 Yr(s)
University of Alberta
Physiological, Anatomical and Molecular Organization of the Cerebellum
BSC ZATORRE, Robert J
SCHONWIESNER, Marc $159,057 5 Yr(s)
McGill University
Montreal Neurological Institute
Mapping the human auditory cortex: low-level features and higher-order interactions
CBM BENNETT, Steffany A BAETZ, Kristin K $107,070 5 Yr(s)
FIGEYS, Daniel
University of Ottawa
Lipidomics of neurodegenerative disease: A systems and cell biology approach to reverse neuronal vulnerability
CBM BERGERON, John J NILSSON, Tommy J $264,865 5 Yr(s)
McGill University
The Molecular Cytology of Membrane Dynamics
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
16
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
CBM CARRENO, Sébastien $132,683 5 Yr(s)
Université de Montréal
Institute for Research in Immunology and Cancer (Montreal, QC)
Role of the Phosphoinositides and Moesin on the Actin/Microtubule crosstalk during cell division.
CBM CHEN, Wayne S
$86,495 3 Yr(s)
University of Calgary
Understanding the Molecular Defects and Treatment of Human Malignant Hyperthermia and Central Core Disease
CBM DESJARDINS, Michel THIBAULT, Pierre $158,113 5 Yr(s)
Université de Montréal
The phagosome proteome and systems biology: insights into novel phagosome functions
CBM LEE, Stephen COTE, Jocelyn $149,124 5 Yr(s)
University of Ottawa
Anaerobic Nucleolar Proteome Dynamics
CBM MAYOR, Thibault $101,424 5 Yr(s)
University of British Columbia
Proteomic Analysis of the Ubiquitin Proteasome System and the Protein Quality Control Machinery
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
17
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
CBM OHH, Michael $110,596 5 Yr(s)
University of Toronto
Role of HIF in Endocytosis
CBM ROKEACH, Luis A $112,338 3 Yr(s)
Université de Montréal
The endoplasmic reticulum and programmed cell death
CBM ROSKAMS, Angela J $151,033 5 Yr(s)
University of British Columbia
Regulation of Brain Lipid Binding Protein in Growth-Promoting Glia
ROUCOU, Xavier
CBM $141,210 5 Yr(s)
Université de Sherbrooke
Molecular activity of prion protein oligomers in health and diseases
CBM ZACKSENHAUS, Eldad $149,253 5 Yr(s)
University Health Network (Toronto)
Effect of pRb phosphorylation on development and disease
CBT BRAND, Marjorie C $149,655 3 Yr(s)
Ottawa Health Research Institute
Epigenetic Regulation of Erythropoiesis by the MLL Family of Proto-oncogenes
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
18
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
CBT DICK, Frederick A $118,193 3 Yr(s)
University of Western Ontario
London Health Sciences Centre (London, Ontario)
Differential control of E2F transcription factors by pRB in normal and cancer cells
CBT DROBETSKY, Elliot A $116,014 3 Yr(s)
Hôpital Maisonneuve-Rosemont (Montréal)
Cell cycle-specific regulation of nucleotide excision repair in human cells
CBT GUÉRIN, Brigitte APARICIO, Samuel J / RUTH, Thomas J
 $108,186 3 Yr(s)
BENARD, Francois
Université de Sherbrooke
Radiolabelled peptides to improve cancer diagnosis by positron emission tomography / Peptides radiomarqués pour améliorer le diagnostic du cancer par tomographie à émission de positron
CBT LAPOINTE, Réjean PICCIRILLO, Ciriaco A $138,780 3 Yr(s)
Centre Hosp. de l'Université de Montréal (CHUM)
Defining immunological checkpoints to enhance cancer immunotherapy
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
19
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
CBT LE, Xiaochun C WEINFELD, Michael $128,871 3 Yr(s)
University of Alberta
Mechanisms of arsenic carcinogenesis
CBT SHAH, Girish M GRAZIANI, Grazia / PASIEKA, Janice L
 $156,347 4 Yr(s)
Université Laval
Centre hospitalier de l'Université Laval (Québec)
Potentiation of chemotherapy of neuroendocrine carcinoid tumors by PARP-inhibitors
CBT SLEIMAN, Hanadi AUTEXIER, Chantal / MOITESSIER, Nicolas R
 $103,673 3 Yr(s)
McGill University
Supramolecular Complexes as G-Quadruplex Binders: Towards Effective Telomerase Inhibition
CBT WAGNER, James R CADET, Jean $107,402 3 Yr(s)
Université de Sherbrooke
DNA repair and mutagenic potential of oxidized cytosine and 5-methylcytosine
CHI BRESSMANN, Tim KULKARNI, Gajanan V $73,178 3 Yr(s)
University of Toronto
Tactile and visual biofeedback in the therapy of compensatory cleft palate articulation
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
20
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
CHI CHAMBERS, Christine T MCGRATH, Patrick J / MOORE, Christopher / MORRONGIELLO, Barbara A / YANCHAR, Natalie L
 $105,752 5 Yr(s)
IWK Health Centre (Halifax)
Everyday Pains in Young Children
CHI FORGET, Robert GAGNON, Isabelle $137,161 5 Yr(s)
FAUBERT, Jocelyn
MCKERRAL, Michelle
Université de Montréal
Visual perception deficits in children after mild traumatic brain injury: psychophysics, electrophysiology and impact on postural stability
CHI GORDON, Karen Ann PAPSIN, Blake C $109,743 4 Yr(s)
Hospital for Sick Children (Toronto)
Processing bilateral electrical input in the developing auditory system
CHI HAMILTON, Jill K HANLEY, Anthony J / RETNAKARAN, Ravi R / ZINMAN, Bernard
 $88,044 5 Yr(s)
Hospital for Sick Children (Toronto)
Insulin resistance and beta cell dysfunction in early childhood: the role of maternal and infant metabolic risk factors
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
21
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
CHI MCGRATH, Jennifer J BROUILLETTE, Robert / CHAPUT, Jean-Philippe / CONSTANTIN, Evelyn / JARRIN, Denise C / KLINE, Rex B / LAMBERT, Marie / PARADIS, Gilles / POIRIER, Paul / TREMBLAY, Angelo
 $270,745 5 Yr(s)
Concordia University (Montreal, Quebec)
Sleep and Obesity in Children and Adolescents: Identifying Pathogenic Pathways
CHI OBERLANDER, Timothy F BOYCE, Thomas W / BRANT, Rollin F / DEVLIN, Angela M / DIAMOND, Adele / GRUNAU, Ruth E / MISRI, Shaila / WEINBERG, Joanne / YOUNG, Allan H
 $122,094 5 Yr(s)
University of British Columbia
Executive Functions and stress reactivity in 5-7 year olds following prenatal serotonin reuptake inhibitor exposure
CHI PANG, Elizabeth W CHEYNE, Douglas O / DE NIL, Luc F / ROBERTS, Sheila (Wendy) G
 $155,242 5 Yr(s)
Hospital for Sick Children (Toronto)
Dissociating cognitive and motor components of healthy and dysfunctional expressive language development in children
CHI SIDEN, Harold B BRANT, Rollin F / CADELL, Susan Anne / DAVIES, Elizabeth M / STRAATMAN, Lynn
 $260,935 5 Yr(s)
STEELE, Rose G
University of British Columbia
Charting the Territory: Determining and Documenting Trajectories for Families Where a Child Has a Life-Threatening Condition
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
22
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
CHI SNIDER, Laurie M BOS, Arend F / MAJNEMER, Annette / MAZER, Barbara L
 $41,011 2 Yr(s)
McGill University
The predictive validity of the general movements assessment of infants born preterm for functional outcomes at six years of age
CHI UNGAR, Michael ANDREOU, Pantelis / CARREY, Normand / DONNON, Tyrone L / LEBLANC, John C / THIESSEN, Victor
 $136,462 5 Yr(s)
Dalhousie University (Nova Scotia)
Adversity and Resilience among early teens: What predicts positive outcomes in later adolescence?
CHI WOODGATE, Roberta L BORTON, Barbara L / EDWARDS, Marie P / HALLMAN, Bonnie C / REMPEL, Gina R / RIPAT, Jacqueline D
 $79,768 3 Yr(s)
University of Manitoba
Changing geographies of care: Using therapeutic landscapes as a framework to understand how families with medically complex children participate in communities
CIA CANIGGIA, Isabella JURISICOVA, Andrea / POST, Martin
 $151,410 5 Yr(s)
Mount Sinai Hospital (Toronto)
The role of Bcl-2 family members in regulating placental cell fate
CIA CHAUHAN, Balwantray C
$161,894 5 Yr(s)
Dalhousie University (Nova Scotia)
Models of Intraocular Pressure and Endothelin- 1 Induced Optic Nerve Damage
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
23
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
CIA CROY, Barbara A ADAMS, Michael A / SMITH, Graeme N
 $154,071 5 Yr(s)
Queen's University (Kingston, Ontario)
Evaluation of natural killer cell contributions to the known, elevated risks for maternal and fetal pathologies in diabetic pregnancy
CIA DAVIDGE, Sandra T $112,150 5 Yr(s)
University of Alberta
Mechanisms for cardiovascular dysfunction in offspring born intrauterine growth restricted
CIA FORTIER, Michel A EL-ALFY, Mohamed $114,506 3 Yr(s)
Université Laval
Centre hospitalier de l'Université Laval (Québec)
Genes and proteins of the prostaglandin sythesis and signalling cascades associated with menstrual disorders
CIA TSUI, Ban C $49,489 3 Yr(s)
University of Alberta
Electrical impedance: a novel approach for detecting intraneural needle placement in regional anesthesia.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
24
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
CIA WONG, Agnes GOLTZ, Herbert C / MIRABELLA, Giuseppe
 $95,673 5 Yr(s)
Hospital for Sick Children (Toronto)
Timing of Surgery for Crossed Eyes in Infancy: A Clinical Evaluation of Sensory and Motor Outcomes
CIB ANTONIOU, John IATRIDIS, James / MWALE, Fackson
 $81,246 3 Yr(s)
Jewish General Hospital (Montreal)
Lady Davis Institute for Medical Research (Mtl)
Quantitative magnetic resonance imaging as a diagnostic tool of intervertebral disc matrix composition and integrity
CIB BROMME, Dieter CULLIS, Pieter R $111,844 3 Yr(s)
University of British Columbia
Cathepsins K and S inhibition in a rheumatoid arthritis murine model
CIB DE BRUM-FERNANDES, Artur J BOIRE, Gilles / PARENT, Jean-Luc
 $92,655 4 Yr(s)
Université de Sherbrooke
Anabolic Properties of Prostaglandin D2 in Human Bone
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
25
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
CIB DUTZ, Jan P $121,076 4 Yr(s)
University of British Columbia
Child and Family Research Institute
Mechanisms of topical TLR activation for the enhancement of immune responses to protein vaccines
CIB EL-GABALAWY, Hani S ELIAS, Brenda D / FERUCCI, Elizabeth D / HITCHON, Carol A / OEN, Kiem G / PESCHKEN, Christine A
 $180,148 5 Yr(s)
University of Manitoba
Early identification of rheumatoid arthritis in First Nations
CIB HILDEBRAND, Kevin A HART, David A / SALO, Paul T
 $140,732 3 Yr(s)
University of Calgary
Neuroinflammatory Mechanisms in Joint Contracture Development
CIB KAARTINEN, Mari T $112,359 3 Yr(s)
McGill University
Matrix crosslinking by Factor XIIIA and transglutaminase 2 during bone formation
CIB KOMAROVA, Svetlana V $115,842 5 Yr(s)
McGill University
Regulation of osteoclast formation and function by cell-cell interactions in the bone microenvironment
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
26
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
CIB MCDONALD, Patrick P $120,990 5 Yr(s)
Université de Sherbrooke
Nuclear signaling in human neutrophils
CIB MOREAU, Robert BRISSETTE, Louise $93,479 4 Yr(s)
Université du Québec à Montréal
Functions of the scavenger receptors of class B in bone metabolism.
CP FISET, Céline $156,739 5 Yr(s)
Montreal Heart Institute
The role of pro-inflammatory cytokines on cardiac repolarization and arrhythmogenesis
GALLIN, Warren J
CP SPENCER, Andrew N $120,477 3 Yr(s)
University of Alberta
Structure/function analysis of voltage-gated potassium channels
CP LYTTON, Jonathan $175,986 5 Yr(s)
University of Calgary
Hippocampal Plasticity: Cellular & Molecular Physiology of the K-Dependent Na/Ca- Exchanger, NCKX2
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
27
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
CP PARENT, Jean-Luc $141,943 5 Yr(s)
Université de Sherbrooke
Regulation of G protein-coupled receptor trafficking
CP SIMS, Stephen M $162,545 5 Yr(s)
DIXON, S. Jeffrey
University of Western Ontario
Role of Cytosolic Calcium in the Regulation of Osteoclasts and Bone Resorption
CP SRAYKO, Martin A $133,672 4 Yr(s)
University of Alberta
Approaches to understand the regulation of microtubules and microtubule motor proteins in mitotic spindle assembly and the positioning of intracellular structures.
CP TANENTZAPF, Guy $112,864 4 Yr(s)
University of British Columbia
Analysis of Integrin Function in Muscle Formation and Maintenance.
CP TEPASS, Ulrich $172,854 5 Yr(s)
University of Toronto
Regulation of epithelial polarity
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
28
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
CP WEEKS, Gerald $146,176 5 Yr(s)
University of British Columbia
The role of Rap1 in regulating cell function
CP WOOD, Janet M $84,731 3 Yr(s)
University of Guelph
Characterization of osmolytes and osmolyte transporters that confer osmotic, thermal, oxidative and urea stress tolerance on Escherichia coli cells
CPT BALLY, Marcel B APARICIO, Samuel J / JONES, Steven / LASKIN, Janessa J / MARRA, Marco A
 $159,178 3 Yr(s)
University of British Columbia
BC Cancer Agency (Vancouver, BC)
SynTarg Discovery Program: Use of a Genome Wide siRNA Screen To Identify Targets that will Enhance Platinum-Containing Chemotherapy when used in First Line Therapy of Non-Small Cell Lung Cancer
BERGER, Stuart A
CPT $104,799 3 Yr(s)
University Health Network (Toronto)
Calpain and calpastatin in leukemia
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
29
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
CPT JABADO, Nada $126,779 3 Yr(s)
The Research Institute of the McGill University Health Centre
Montreal Children's Hospital Research Institute
Identification and characterization of genes involved in the genesis and progression of pediatric astrocytomas.
CPT JEAN-CLAUDE, Bertrand J
$98,685 3 Yr(s)
McGill University
Royal Victoria Hospital (Montreal)
Single molecules engineered for the tandem delivery of Xeloda ® and EGFR/Her2 tyrosine kinase inhibitors: a novel multitargeted approach for the therapy of advanced breast cancers
CPT KASSOUF, Wassim LAPOINTE, Jacques / MANSURE, Jose J
 $128,945 3 Yr(s)
The Research Institute of the McGill University Health Centre
Interrogating the mTOR Signaling Pathway in Bladder Cancer
CPT LIU, Fei-Fei HUI, Angela B / O'SULLIVAN, Brian / PEREZ-ORDONEZ, Bayardo / PINTILIE, Melania
 $150,500 5 Yr(s)
University Health Network (Toronto)
The Role of Micro-RNA's in Human Nasopharyngeal Carcinoma
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
30
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
CPT MES-MASSON, Anne-Marie PROVENCHER, Diane M / TONIN, Patricia N
 $150,500 5 Yr(s)
Centre Hosp. de l'Université de Montréal (CHUM)
Selection and validation of target genes implicated in the clinical and biological features of ovarian cancer
CPT PAQUETTE, Benoît BUJOLD, Rachel / LEPAGE, Martin
 $88,626 3 Yr(s)
Université de Sherbrooke
Improving radiotherapy of breast cancer with the COX-2 inhibitor NS-398
CPT PARISSENTI, Amadeo M
CHAPMAN, Judith-Anne W / CONLON, Michael / KAHN, Harriette / MACLEAN, Dave A / TRUDEAU, Maureen E
 $111,280 3 Yr(s)
Sudbury Regional Hospital (ON)
Aldoketoreductases and Their Role in Tumour Progression and Anthracycline Resistance in Human Breast Cancer
CPT ROSKELLEY, Calvin D
MCNAGNY, Kelly M $111,112 4 Yr(s)
University of British Columbia
The role of the podocalyxin complex in tumor progression.
CPT ST-PIERRE, Yves $97,633 3 Yr(s)
INRS - (Québec, QC)
INRS-Institut Armand-Frappier (Laval)
The role of galectin-7 in mammary tumorigenesis and metastasis
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
31
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
CPT TANNOCK, Ian F $127,822 3 Yr(s)
University Health Network (Toronto)
Princess Margaret Hospital (Toronto)
Repopulation and chemotherapy
CPT TRUS, Micheal R SINGH, Gurmit $123,934 1 Yr(s)
McMaster University
Juravinski Cancer Centre (Hamilton, ON)
Identification of Targets for Novel Acute Myeloblastic Leukemia Treatments
CSA BACKX, Peter H $146,346 5 Yr(s)
University Health Network (Toronto)
Mechanisms for (subcellular) regulation of cAMP in normal and diseased heart
CSA BRINDLEY, David N $144,853 5 Yr(s)
University of Alberta
Control of cardiac fatty acid and glucose metabolism by lipins
CSA FISET, Céline
$170,966 5 Yr(s)
Montreal Heart Institute
Sex hormone-based differences in cardiac electrical activity
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
32
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
CSA ISENRING, Paul $137,063 5 Yr(s)
Université Laval
Hôtel-Dieu de Québec
Molecular mechanisms underlying the normal operation and the physiological role of the renal Na-K-Cl cotransporter splice variants.
CSA KARSAN, Aly $141,043 5 Yr(s)
University of British Columbia
B.C. Cancer Research Centre (Vancouver)
Endothelial to mesenchymal transformation
CSA KIRSHENBAUM, Lorrie A $145,266 5 Yr(s)
University of Manitoba
Molecular Determinants of Apoptosis in Heart
CSA NOSKOV, Sergei DUFF, Henry J $90,743 3 Yr(s)
University of Calgary
Mechanism of the high-affinity ligand binding and selective ion permeation in voltage-gated K-channels
CSA VON HARSDORF, Rudiger $151,886 5 Yr(s)
University Health Network (Toronto)
Cardiac growth control by E2F4
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
33
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
CSB BUTCHER, Kenneth S BEAULIEU, Christian / EMERY, Derek J / JEERAKATHIL, Thomas J / MAJUMDAR, Sumit R / SHUAIB, Ashfaq
 $88,926 3 Yr(s)
University of Alberta
Cerebral Perfusion and Blood Pressure in Acute Ischemic Stroke.
CSB CHALIFOUR, Lorraine E SEBAG, Igal A $108,035 5 Yr(s)
Jewish General Hospital (Montreal)
Steroidal hormone programming in heart.
CSB DENG, Alan Y DEBLOIS, Denis $136,265 3 Yr(s)
Centre Hosp. de l'Université de Montréal (CHUM)
Gene discovery for cardiovascular diseases independent of hypertension
CSB GOLLOB, Michael H $115,982 3 Yr(s)
University of Ottawa
University of Ottawa Heart Institute
Connexin Defects and Mechanistic Insight into the Vunerability of Atrial Fibrillation
CSB HAMET, Pavel ORLOV, Sergei N / SEDA, Ondrej
 $164,614 5 Yr(s)
Centre Hosp. de l'Université de Montréal (CHUM)
Hypertension at nexus of the thrifty, thirsty and accelerated ageing genotypes: evolution of a complex disease
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
34
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
CSB LOPASCHUK, Gary D $124,577 5 Yr(s)
University of Alberta
Energy substrate metabolism in the ischemic and non-ischemic heart
CSB MCNEILL, John H $131,174 3 Yr(s)
University of British Columbia
Malonyl CoA-Independent Regulation of Carnitine Palmitoyltransferase-1 by ß adrenoceptor Signalling in the Heart
CSB NANTHAKUMAR, Kumaraswamy $136,187 5 Yr(s)
University Health Network (Toronto)
Mechanisms and Modulation of Spatio- temporal Organization of Human Ventricular Fibrillation
CSB REUDELHUBER, Timothy L $125,214 3 Yr(s)
Institut de recherches cliniques de Montréal
Prorenin in health and disease
CSB WARD, Michael E $129,900 3 Yr(s)
BACKX, Peter H
St. Michael's Hospital (Toronto)
Oxygen Regulation of Membrane Potential by a GTP-gated Chloride Current in Proliferating Pulmonary Artery Smooth Muscle.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
35
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
CSB YAN, Andrew T DICK, Alexander J / GOLDSTEIN, Marc / LEONG-POI, Howard M / WU, Louis
 $101,376 3 Yr(s)
WALD, Ron
St. Michael's Hospital (Toronto)
Impact of in-centre nocturnal hemodialysis on ventricular remodeling and function in end- stage renal disease
CSC BONNET, Sébastien $118,500 5 Yr(s)
University of Alberta
Experimental therapies for vascular remodeling diseases
CSC COUTTS, Shelagh B DEMCHUK, Andrew M / ELIASZIW, Michael / FRAYNE, Richard / GOYAL, Mayank / HILL, Michael D
 $122,798 3 Yr(s)
University of Calgary
CT And MRI in the Triage of TIA and minor Cerebrovascular events to identify High risk patients. (CATCH)
CSC CYBULSKY, Myron I $146,813 5 Yr(s)
University Health Network (Toronto)
Functions of alpha-4 integrins in monocyte emigration.
CSC DIXON, Ian Michael C $102,611 5 Yr(s)
University of Manitoba
Regulation of extracellular matrix by myofibroblasts in cardiac hypertrophy and failure
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
36
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
CSC GIROUARD, Hélène $121,688 3 Yr(s)
Université de Montréal
Astrogliosis in Angiotensin II-induced neurovascular uncoupling.
CSC MOURAD, Walid M HASSAN, Ghada / MERHI, Yahye
 $129,817 5 Yr(s)
Centre Hosp. de l'Université de Montréal (CHUM)
Role of CD40 ligand in athero-thrombosis.
CSC THORIN, Eric
FERLAND, Guylaine / HAMEL, Edith
 $115,163 3 Yr(s)
Montreal Heart Institute
Risk factors for cardiovascular diseases and cerebrovascular function
DEV AKIMENKO, Marie-Andrée $138,280 5 Yr(s)
Ottawa Health Research Institute
Control mechanisms of fin regeneration in zebrafish
DEV BHATIA, Mickie $159,893 5 Yr(s)
McMaster University
Characterization of the human embryonic stem cell niche
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
37
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
DEV EKKER, Marc $176,231 5 Yr(s)
University of Ottawa
Regulation and function of Dlx homeobox genes in the developing forebrain of vertebrates.
DEV HEKIMI, Siegfried $104,712 3 Yr(s)
McGill University
Genetics of lipoprotein metabolism in C. elegans
DEV HOODLESS, Pamela A
$146,839 3 Yr(s)
University of British Columbia
B.C. Cancer Research Centre (Vancouver)
Formation and Patterning of the Definitive Endoderm
DEV LIPSHITZ, Howard D $165,858 5 Yr(s)
University of Toronto
Post-transcriptional gene regulation during Drosophila development
DEV LOHNES, David L $196,495 5 Yr(s)
University of Ottawa
Novel roles for Cdx proteins in development
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
38
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
DEV SCHUURMANS, Carol J $135,115 5 Yr(s)
University of Calgary
Molecular regulation of layer formation in the developing CNS
DS NANCI, Antonio $110,882 5 Yr(s)
MOFFATT, Pierre
SMITH, Charles E
Université de Montréal
Functional studies and experimental manipulation of ameloblastin expression
DS OVERALL, Christopher M $196,783 5 Yr(s)
University of British Columbia
Leukocyte Matrix Metalloproteinases (MMPs) in Arthritis
DS UNDERHILL, T. Michael $139,953 5 Yr(s)
University of British Columbia
Delineating the Molecular Mechanisms Underlying BMP Action
E CASPER, Robert F
BROWN, Theodore J / SHAPIRO, Colin M
 $143,607 3 Yr(s)
Mount Sinai Hospital (Toronto)
Samuel Lunenfeld Research Institute (Toronto)
Prevention of Circadian Rhythm Disruption by Nocturnal Light Exposure
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
39
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
E CROSS, James C $193,149 5 Yr(s)
University of Calgary
Biology of Trophoblast Giant Cells
E HAN, Victor Khin M GUPTA, Madhulika B / IOSEF, Cristiana
 $155,831 5 Yr(s)
University of Western Ontario
Regulation of Fetal Growth
E LABRIE, Claude
$138,651 5 Yr(s)
Université Laval
Centre hospitalier de l'Université Laval (Québec)
Molecular mechanism of action of the membrane-bound transcription factor AIbZIP
E LIN, Sheng-Xiang POIRIER, Donald $125,715 5 Yr(s)
Université Laval
Centre hospitalier de l'Université Laval (Québec)
Estrogenic 17beta-hydroxysteroid dehydrogenases contributing to breast cancer stimulation: 3D-structure, function and inhibition
E MURPHY, Bruce D $147,932 5 Yr(s)
Université de Montréal
Ovarian cell differentiation
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
40
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
E PENG, Chun SHAW, Patricia A $133,300 3 Yr(s)
York University (Toronto, Ontario)
The integrative role of Nodal, cyclin G2 and miR-376c in ovarian tumorigenesis
E ROBAIRE, Bernard NAGANO, Makoto $148,322 5 Yr(s)
McGill University
Aging of male germ cells
E SADAR, Marianne D ANDERSEN, Raymond J / WANG, Yuzhuo
 $151,203 3 Yr(s)
University of British Columbia
B.C. Cancer Research Centre (Vancouver)
Discovery of new drug candidates for the clinical management of prostate cancer
E SULLIVAN, Robert $127,184 3 Yr(s)
Université Laval
Sperm proteins acquired during epididymal transit: functions and usefulness for diagnostic of man infertility
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
41
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
ELH COWARD, Harold G AGUPIO, Godfrey / ATTIG, Thomas W / BRUCE, W. A / CLARK, David / CLOUSTON, Joyce / DAVIES, Elizabeth M / FLORIDA, Robert E / HADLEY, Michael L / HUI, Edwin C / KAUFERT, Joseph M / NAYAR, Kamala E / RAMBACHAN, Anantanand / RAVVIN, Norman / SOSKICE, Janet C / WAUGH, Earle H
 $51,641 3 Yr(s)
STAJDUHAR, Kelli I
University of Victoria (British Columbia)
Religious Requirements for a "Good Death" in Hospice Care
MITCHINSON, Wendy L
ELH $55,368 3 Yr(s)
University of Waterloo (Ontario)
History of Obesity in Canada, 1920-1980
ELH TALJAARD, Monica BORUCH, Robert F / BREHAUT, Jamie C / BROWN, Judith B / DONNER, Allan / ECCLES, Martin P / SAGINUR, Raphael / ZWARENSTEIN, Merrick F
 $93,996 3 Yr(s)
GRIMSHAW, Jeremy M
WEIJER, Charles E
Ottawa Health Research Institute
Ethical and policy issues in cluster randomized trials
EM BOUDREAU, François $138,284 3 Yr(s)
Université de Sherbrooke
Functional role of specific transcriptional regulators during intestinal epithelial development and maintenance
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
42
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
EM CARRIER, Julie $101,558 3 Yr(s)
Université de Sherbrooke
The role of the estrogen-related receptors alpha (ERRalpha) in the normal and cancerous intestine
EM CHEN, Xing-Zhen $140,382 5 Yr(s)
University of Alberta
Polycystin-2: cellular function, regulation and mechanism of renal cyst progression
EM DICK, John E $161,250 5 Yr(s)
University Health Network (Toronto)
Molecular and cellular characterization of early human hematopoietic lineage determination
EM HEATHCOTE, Elizabeth Jane J
SIMINOVITCH, Katherine A $245,508 3 Yr(s)
University Health Network (Toronto)
Toronto Western Hospital
Molecular Dissection of Primary Biliary Cirrhosis
EM HEBERT, Marie-Josée BENDAYAN, Moise $116,202 3 Yr(s)
Centre Hosp. de l'Université de Montréal (CHUM)
Characterization of non-classical protein secretion pathways of importance in the fibrogenic paracrine response triggered by apoptosis
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
43
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
EM KARSAN, Aly $159,805 5 Yr(s)
University of British Columbia
B.C. Cancer Research Centre (Vancouver)
Innate immune signaling in hematopoiesis
EM LEVY, Emile DELVIN, Edgard E $140,325 5 Yr(s)
Hôpital Sainte-Justine (Montréal)
Gaining insight into cholesterol homeostasis in the small intestine: a special role for PCSK9
EM ROSENBLUM, Norman D $155,828 5 Yr(s)
Hospital for Sick Children (Toronto)
Control of kidney cell determination and morphogenesis by BMPs and Beta-catenin
EM VON DER WEID, Pierre-Yves $137,832 5 Yr(s)
University of Calgary
Mechanisms of Distension-Activated Contractility in Lymphatic Vessels: Importance for edema resolution
EM WALLACE, John L $158,609 5 Yr(s)
University of Calgary
NSAID Gastropathy and Cytoprotection
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
44
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
G BULMAN, Dennis E WALLACE, Valerie A $170,082 5 Yr(s)
Ottawa Health Research Institute
Identification of a novel gene for brachydactyly- A1
G GRUENHEID, Samantha L $113,468 5 Yr(s)
McGill University
Genetic dissection of the host response to intestinal infections
G LORINCZ, Matthew C
$148,481 5 Yr(s)
University of British Columbia
Analysis of the Interplay Between Histone MTases, DNA Methylation and Proviral Silencing
G OSBORNE, Lucy R
$130,190 5 Yr(s)
University of Toronto
Genetic analysis of Williams-Beuren syndrome: linking genes with cognition and behaviour
G PASTINEN, Tomi HARVEY, Edward J / RICHARDS, Brent
 $129,000 3 Yr(s)
McGill University
Genomewide analysis of functional polymorphisms affecting human bone phenotypes
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
45
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
G PEI, York P PATERSON, Andrew D $132,526 3 Yr(s)
University of Toronto
Molecular Genetics of IgA Nephropathy
G POLYCHRONAKOS, Constantin $143,250 3 Yr(s)
The Research Institute of the McGill University Health Centre
Novel genetic susceptibility loci for type 1 diabetes
G SKAMENE, Emil
FORTIN, Anny / GROS, Philippe / SLADEK, Robert G / VIDAL, Silvia M
 $199,262 5 Yr(s)
The Research Institute of the McGill University Health Centre
Genetic Dissection of Host Response Against Respiratory Virus Infections in Recombinant Congenic Strains of Mice
G TRIGGS-RAINE, Barbara L $151,222 5 Yr(s)
University of Manitoba
Constitutive and regulated pathways of hyaluronan degradation
G WEKSBERG, Rosanna ROBERTS, Sheila (Wendy) G / SCHERER, Stephen W
 $186,196 3 Yr(s)
Hospital for Sick Children (Toronto)
Genome-Wide DNA Methylation Profiling in Autism
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
46
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
GMX CHUA, Gordon $129,473 5 Yr(s)
University of Calgary
Deciphering pathways of transcriptional regulation in Schizosaccharomyces pombe
GMX EDWARDS, Aled M MAXWELL, Karen L $275,786 5 Yr(s)
University of Toronto
Functional and Structural Genomics of Bacteriophage
GMX FOSTER, Leonard J
$122,768 5 Yr(s)
University of British Columbia
A global view of host cell manipulation by Salmonella
GMX HUGHES, Timothy R $218,492 5 Yr(s)
University of Toronto
Comprehensive analysis of mouse and human transcription factor DNA-binding specificities
GMX ROBERT, François COULOMBE, Benoît $137,699 1 Yr(s)
Institut de recherches cliniques de Montréal
Systematic characterization of the proteome associated with specific genomic loci: A proof of concept
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
47
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
GMX ROGER, Andrew J SIMPSON, Alastair G $143,876 5 Yr(s)
Dalhousie University (Nova Scotia)
Major transitions in eukaryotic cell evolution.
GMX STANFORD, William L $315,949 5 Yr(s)
BADER, Gary D
MORRIS, Quaid D
ZANDSTRA, Peter W
University of Toronto
Transcription Networks Controlling Human Embryonic Stem Cell Fate
GMX WILKINSON, Mark D MCMANUS, Bruce M $133,178 4 Yr(s)
University of British Columbia
St. Paul's Hospital, Vancouver
CardioSHARE: Design of an integrated query and analysis framework for ischemic heart disease data
GSH BAILLARGEON, Raymond H KEENAN, Kathryn / LEFEBVRE, Francine
 $60,000 2 Yr(s)
University of Ottawa
The Origins of Gender Differences in Disruptive Behavior Problems II
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
48
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
GSH BERMAN, Helene A CLASSEN, Catherine C / LANIUS, Ruth A / MACARTHUR-EVANS, Marilyn K / RODGER, Susan C / ROSS, Lori E
 $73,920 3 Yr(s)
MASON, Robin A
University of Western Ontario
Embodied Trauma: The Influence of Past Trauma on Women During the Transition to Motherhood
GSH BERNARD, Daniel J BOERBOOM, Derek Theodoor
 $159,619 5 Yr(s)
McGill University
Transcriptional regulation of follicle stimulating hormone synthesis
GSH GALDAS, Paul M GREWAL, Sukhdev K / JOHNSON, Joy L / RATNER, Pamela A / WONG, Sabrina
 $55,905 3 Yr(s)
OLIFFE, John L
University of British Columbia
Unpacking the effects of gender and ethnicity on healthcare utilization: The cardiac rehabilitation experiences of Indo-Canadian Men
GSH GRANT, Denis M $119,798 3 Yr(s)
University of Toronto
Gender, genes and risk for arylamine-induced cancers: animal models and mechanisms
GSH KAUL, Padmaja R ARMSTRONG, Paul W / GRAHAM, Michelle M / NORRIS, Colleen / WELSH, Robert C
 $131,706 3 Yr(s)
University of Alberta
Tracking gender differences in acute coronary syndromes: At the first point of care and beyond
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
49
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
GSH LETOURNEAU, Nicole L BENZIES, Karen M / DENNIS, Cindy-Lee E / DOUCET, Andrea M / DUFFETT-LEGER, Linda A / MCGRATH, Patrick J / STEWART, Miriam J
 $86,835 2 Yr(s)
University of New Brunswick (Fredericton)
Support for Fathers Affected by Postpartum Depression
GSH TRASLER, Jacquetta M NAGANO, Makoto / ZINI, Armand S
 $161,694 5 Yr(s)
The Research Institute of the McGill University Health Centre
Montreal Children's Hospital Research Institute
Sex-specific susceptibility for fetal origins of adult disease and transgenerational effects
HPM LYND, Larry D MAIL, Walter J / MARRA, Carlo A / TAYLOR, Jeff G / TSUYUKI, Ross T
 $53,431 2 Yr(s)
University of British Columbia
Study of Understanding Patients' Preferences on Remuneration and Transition Towards Pharmacists' Provision of Chronic Disease Management (SUPPORT 2)
HPM MINTZES, Barbara J BARER, Morris L / BASSETT, Kenneth L / BEAULIEU, Marie- Dominique / CASSELS, Alan K / DURRIEU, Geneviève / MORGAN, Steven G / TEJANI, Aaron M / WILKES, Michael / WRIGHT, James M
 $141,119 2 Yr(s)
LEXCHIN, Joel
University of British Columbia
Pharmaceutical sales representatives and patient safety: comparative cross-sectional survey
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
50
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
HPM POMEY, Marie-Pascale A CARPENTIER, Normand C / FOREST, Pierre-Gerlier / HUDON, Raymond / LAVIS, John N
 $76,486 3 Yr(s)
Université de Montréal
Anatomy of Quebec's Decision-Making Process: The Chaoulli Decision
HSI BELL, Scott M MUHAJARINE, Nazeem / RAMSDEN, Vivian R / WILSON, Kathleen J
 $98,414 3 Yr(s)
University of Saskatchewan
Examining Access to Health Care at the Neighbourhood Level
HSI CLARK, Alexander M
CHAN, Michael C / EZEKOWITZ, Justin A / KASZA, Leslie A / MCALISTER, Finlay A / STRAIN, Laurel A / TSUYUKI, Ross T
 $88,802 2 Yr(s)
University of Alberta
Improving heart failure outcomes in rural communities: Moving from understanding to practice change
HSI JOHNSON, Jeffrey A
VEUGELERS, Paul J / YASUI, Yutaka
 $68,755 2 Yr(s)
MARRA, Carlo A
University of Alberta
Cancer incidence for patients with Type 2 Diabetes exposed to oral hypoglycemics: Are there differences between agents?
HSI LACAILLE, Diane V ABRAHAMOWICZ, Michal M / ANIS, Aslam H / ESDAILE, John M / TUGWELL, Peter S
 $115,543 2 Yr(s)
The Arthritis Research Centre of Canada
Assessing the quality of care for rheumatoid arthritis at a population level
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
51
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
HSI NATHENS, Avery B MORRISON, Laurie J / RUBENFELD, Gordon
 $119,787 1 Yr(s)
St. Michael's Hospital (Toronto)
Trauma system design: an evaluation of structure and process
HSI ROCHON, Paula A ANDERSON, Geoffrey M / BELL, Chaim M / BRONSKILL, Susan E / GRUNEIR, Andrea / SCHULL, Michael J
 $76,116 3 Yr(s)
Baycrest Centre for Geriatric Care (Toronto)
Emergency Department Visits by Nursing Home Residents in Ontario: Descriptive Patterns of Resident Visits by Timing, Location, and Physician Availability
HSI STOLEE, Paul BERG, Katherine O / BYRNE, Kerry / CHESWORTH, Bert M / COOK, Richard J / EGAN, Mary Y / FORBES, Dorothy A / HIRDES, John P / JAGLAL, Susan B / POSS, Jeff W / WELLS, Jennie / ZHU, Mu
 $127,524 2 Yr(s)
University of Waterloo (Ontario)
Enhancing home care rehabilitation through better use of health information
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
52
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
HSR BAUCH, Christopher T ANONYCHUK, Andrea / COLGAN, Terence J / HOWLETT, Robbi (Roberta) / JOHN-BAPTISTE, Ava A / SANDER, Beate H
 $76,046 3 Yr(s)
GILCA, Vladimir
KRAHN, Murray D
MAI, Verna
MCLACHLIN, Catherine (Meg) M
PHAM, Ba'
University of Guelph
Cervical cancer screening in the era of HPV vaccination: using mathematical and economic models to guide screening policy
HSR BAYOUMI, Ahmed M ANTONIOU, Tony / HOCH, Jeffrey S / PARK-WYLLIE, Laura / STRIKE, Carol J / TABACK, Nathan A
 $130,723 2 Yr(s)
St. Michael's Hospital (Toronto)
Preference Measures for HIV Antiretroviral Decision Making
HSR BELL, Chaim M BIERMAN, Arlene S / BRONSKILL, Susan E / ETCHELLS, Edward E / FERNANDES, Olavo A / MAMDANI, Muhammad / ROCHON, Paula A / URBACH, David R
 $63,057 3 Yr(s)
St. Michael's Hospital (Toronto)
Unintentional discontinuation of chronic medications for seniors in long-term care facilities: An evaluation of a medication reconciliation and quality improvement strategy
HSR DIXON, Elijah
BRIEN, Susan E / GHALI, William A / SEIDEL, Judy E / SIMUNOVIC, Marko
 $145,874 3 Yr(s)
University of Calgary
Rates and Waits for Cancer Surgery in Canada: A Mixed Method Assessment
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
53
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
HSR GROOTENDORST, Paul V RACINE, Jeffrey S $106,370 2 Yr(s)
University of Toronto
Assessment of the cost and equity of different catastrophic drug insurance options for Canadians
HSR HAGGERTY, Jeannie L BEAULIEU, Marie- Dominique / HUDON, Catherine / LOIGNON, Christine / PREVILLE, Michel / ROBERGE, Danièle
 $161,880 4 Yr(s)
FORTIN, Martin
Université de Sherbrooke
At the interface of the community and the healthcare system: a longitudinal cohort to study evolving health and the impact of primary healthcare from the patient perspective.
HSR LYND, Larry D FITZGERALD, J M / LAM, Stephen / MARRA, Carlo A / SIN, Donald
 $57,628 2 Yr(s)
University of British Columbia
Evaluating the Association Between Inhaled Corticosteroid and Statin Use and the Development of Lung Cancer in COPD Patients: A Linked Health Database Study
HSR SIDANI, Souraya CAIRNEY, John / MIRANDA, Joyal / STREINER, David L
 $48,663 2 Yr(s)
Ryerson University (Toronto)
Influence of Treatment Attributes on Preferences for Behavioral and Pharmacological Treatments
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
54
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
HSR URBACH, David R BAXTER, Nancy N / LIX, Lisa M / SIMUNOVIC, Marko / SUTRADHAR, Rinku
 $209,445 5 Yr(s)
University Health Network (Toronto)
Structures and Processes of Care in Colorectal Cancer Surgery (SPoCCS) Study
IT ARNOLD, Donald M CROWTHER, Mark A / KELTON, John G / LARCHE, Mark / SNIDER, Denis P
 $109,229 2 Yr(s)
McMaster University
The effect of rituximab on the humoral immune response to S. pneumoniae and H. influenzae type b vaccines in patients with immune thrombocytopenic purpura
IT BLEACKLEY, Robert C $178,948 5 Yr(s)
University of Alberta
Lymphocyte Proteinases
IT LEVESQUE, Eric
$125,387 3 Yr(s)
Université Laval
Hematopoietic stem cell (HCT) transplantation: Identification of key determinants of graft- versus-host disease.
IT MARTIN, Alberto
GOMMERMAN, Jennifer L $124,050 4 Yr(s)
University of Toronto
The Molecular Basis for Germinal Center Selection
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
55
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
IT MOURAD, Walid M $101,145 5 Yr(s)
Centre Hosp. de l'Université de Montréal (CHUM)
The impacts of disulfide bond CD40/CD40 dimers in the biological responses.
IT ZAPH, Colby $119,970 5 Yr(s)
University of British Columbia
Memory TH2 cell responses during helminth infection
IT ZHANG, Li $177,360 5 Yr(s)
University Health Network (Toronto)
Molecular Mechanisms of DN regulatory T cell- mediated donor specific transplantation tolerance.
IT ZUNIGA-PFLUCKER, Juan C $137,013 5 Yr(s)
Sunnybrook Health Sciences Centre
Study of pre-T cell receptor signals regulating thymocyte differentiation.
KTE AHMED, Sara BARTLETT, Susan J / ERNST, Pierre-Paul / GRAD, Roland M / PARÉ, Guy / PERREAULT, Robert / PINSONNEAULT, Alain / TAYLOR, Laurel K
 $69,898 2 Yr(s)
6 Mths
McGill University
Facilitating patient self-management in chronic disease: Integrating electronic personal health records and ongoing communication into a web- based self-management tool
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
56
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
KTE GRIMSHAW, Jeremy M BROUWERS, Melissa C / DRIEDGER, S. Michelle / ECCLES, Martin P / FRANCIS, Jillian J / GODIN, Gaston / HANNA, Steven E / HUX, Janet E / JOHNSTON, Marie / LEGARE, France / LEMYRE, Louise / POMEY, Marie-Pascale A / SALES, Anne E / ZWARENSTEIN, Merrick F
 $193,768 3 Yr(s)
Ottawa Health Research Institute
Canada Prime Plus: Selecting individual and organizational theories for interventions to change clinical practice
KTE HACK, Thomas F DEGNER, Lesley F / GRENIER, Debjani / LATOSINSKY, Steven / RUETHER, Joseph D / WEIR, Lorna
 $112,793 3 Yr(s)
University of Manitoba
Addressing "evidence" and "context" to facilitate the transfer and uptake of consultation recording use in oncology: A knowledge translation implementation study
KTE LEGARE, France ELWYN, Glyn / FROSCH, Dominick L / GRIMSHAW, Jeremy M / LABRECQUE, Michel / OUIMET, Mathieu / ROUSSEAU, Michel / STACEY, Dawn / STEWART, Moira A / VAN DER WEIJDEN, Trudy
 $108,922 2 Yr(s)
6 Mths
Université Laval
EXACKTE 2: Exploiting the clinical consultation as a knowledge transfer and exchange environment
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
57
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
KTE LEHOUX, Pascale N DENIS, Jean-Louis / MILLER, Fiona A / URBACH, David R / WILLIAMS-JONES, Bryn
 $88,143 1 Yr(s)
6 Mths
Université de Montréal
Judgments and health innovation: How do upstream knowledge transfer and exchange among stakeholders contribute to the design of innovations
M GAISANO, Herbert Y OSBORNE, Lucy R $120,271 5 Yr(s)
University of Toronto
Distinct insulin exocytotic actions of Syntaxins- 1 and -2
M GIACCA, Adria $122,408 5 Yr(s)
University of Toronto
Mechanisms of fat-induced hepatic insulin resistance in vivo
M HUFF, Murray W $135,198 4 Yr(s)
University of Western Ontario
Robarts Research Institute - U.W.O. (London, Ont.)
Regulation of Foam Cell Formation: Relationship to Atherosclerosis
M JIN, Tianru $112,724 5 Yr(s)
University Health Network (Toronto)
Mechanisms underlying the production and homeostasis of the incretin hormone GLP-1
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
58
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
M KISS, Robert S YAO, Zemin $105,629 3 Yr(s)
The Research Institute of the McGill University Health Centre
Understanding of regulated intracellular cholesterol movement and cell growth through interplay between LRP1 and its adapter proteins
M RICHARD, Denis $92,437 5 Yr(s)
Université Laval
Institut universitaire de cardiologie et pneumologie de Québec
The Role of the Melanin-Concentrating Hormone System in the Regulation of Energy Balance
M ROZAKIS ADCOCK, Maria WHEELER, Michael B $79,765 3 Yr(s)
University of Toronto
Role of PHIP in Beta Cell Function
M VANCE, Dennis E $167,668 5 Yr(s)
University of Alberta
Phosphatidylcholine metabolism and obesity
M WANG, Rennian $131,229 3 Yr(s)
University of Western Ontario
Determination of the Mechanisms by which the c-Kit Tyrosine Kinase Receptor Regulates Pancreatic Beta Cell Development, Function and Survival.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
59
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
MCC CHARTRAND, Pascal $121,819 4 Yr(s)
Université de Montréal
Telomerase trafficking and maintenance of genome integrity
MCC DUBOIS, Claire M $133,673 3 Yr(s)
Université de Sherbrooke
Furin trafficking in cancer invasion and metastasis
MCC DUROCHER, Daniel
$157,689 5 Yr(s)
Mount Sinai Hospital (Toronto)
Deciphering a novel ubiquitin-dependent signaling pathway during the DNA damage response
MCC EGAN, Sean E
ZACKSENHAUS, Eldad $147,008 4 Yr(s) Pending
Hospital for Sick Children (Toronto)
Genetic Analysis of Jagged & Notch1, genes implicated in aggressive breast cancer
MCC JOLICOEUR, Paul $126,721 5 Yr(s)
Institut de recherches cliniques de Montréal
Oncogenes and the interaction of retroviruses with the host
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
60
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
MCC LEE, Stephen $158,919 5 Yr(s)
University of Ottawa
Understanding the HIF2a Oncogenic Pathway in Human Cancer
MCC LIU, Johne X $147,559 5 Yr(s)
Ottawa Health Research Institute
Cdc42 Regulates Asymmetric Cytokinesis in Polar Body Extrusion
MCC MAI, Sabine
$98,978 3 Yr(s)
University of Manitoba
The role of chromosome 11 in v-abl/myc- induced mouse plasmacytomagenesis
MCC MULLER, William J $128,630 5 Yr(s)
McGill University
The role of phosphatidylinositol-3 kinase (PI3K) coupled signaling pathways in mammary tumorigenesis
MCC POSTOVIT, Lynne-Marie $127,001 5 Yr(s)
University of Western Ontario
Role of Oxygen as a Regulator of Tumour Cell Plasticity and Metastatic Potential
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
61
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
MCC ROSEN, Kirill V LEE, Patrick W $112,459 3 Yr(s)
Dalhousie University (Nova Scotia)
Anti-apoptotic mechanisms that mediate ras oncogene-driven tumor growth
MI COUSINEAU, Benoit OLIVIER, Martin $130,464 3 Yr(s)
McGill University
Development of a new generation of live vaccines using Lactococcus lactis
MI DEVINNEY, Rebekah
$116,190 3 Yr(s)
University of Calgary
Subversion of host cell signalling by Vibrio parahaemolyticus
MI FINLAY, Barton B $170,427 5 Yr(s)
University of British Columbia
Salmonella Spi 2 Type III effectors that alter host cellular functions
MI GUTTMAN, Julian A $110,037 3 Yr(s)
Simon Fraser University (Burnaby, B.C.)
The Role of Endocytic Proteins at Bacteria- Induced Pedestals
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
62
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
MI NANO, Francis E BORASTON, Alisdair B / GUTTMAN, Julian A
 $158,771 4 Yr(s)
University of Victoria (British Columbia)
Type six secretion system of the Francisella Pathogenicity Island
MI NITZ, Mark $86,873 3 Yr(s)
University of Toronto
De-N-acetylases in bacterial biofilm formation: The specificity, mechanism, and inhibition of IcaB and PgaB
MI ROWE-MAGNUS, Dean A $106,550 4 Yr(s)
Sunnybrook Health Sciences Centre
Evolution of CPS and LPS diversity in V. vulnificus
MI SHERMAN, Philip M
$150,500 5 Yr(s)
Hospital for Sick Children (Toronto)
Epithelial cell signalling responses to attaching- effacing intestinal pathogens
MI SURETTE, Michael G $107,666 5 Yr(s)
University of Calgary
Polymicrobial Infections and Pathogenesis of the Streptococcus Milleri Group
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
63
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
MOV BROWNSTONE, Robert M $128,731 5 Yr(s)
Dalhousie University (Nova Scotia)
Control of movement: Brain stem control of locomotion
MOV FRENETTE, Jérôme $98,013 4 Yr(s)
Université Laval
Biological integration of tendon healing:new approaches to understand and accelerate tendon repair
MOV GALLOUZI, Imed $135,584 5 Yr(s)
McGill University
The RNA binding protein HuR is a key player in muscle cell differentiation
MOV MILNER, Theodore E
$70,372 2 Yr(s)
McGill University
Efficacy of robot-assisted rehabilitation of hand function after stroke
MOV NALBANTOGLU, Joséphine $105,136 4 Yr(s)
KARPATI, George
McGill University
Molecular therapies for dystrophin deficiency
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
64
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
MOV ROSSIGNOL, Serge $174,786 5 Yr(s)
Université de Montréal
Adaptive mechanisms of spinal locomotion
MOV SADIKOT, Abbas F $131,897 5 Yr(s)
McGill University
Montreal Neurological Institute
Mechanisms by which Afferents Regulate Striatal Neuronal Loss and Motor Activity in Movement Disorders
MOV VACRATSIS, Panayiotis $81,614 3 Yr(s)
University of Windsor (Ontario)
Molecular mechanisms regulating myotubularin-related lipid phosphatases mutated in neuromuscular diseases
MPI BEDELL, Barry J EVANS, Alan C / PIKE, G. Bruce / ROSA-NETO, Pedro / STANIMIROVIC, Danica
 $158,224 4 Yr(s)
McGill University
Montreal Neurological Institute
Multi-parametric imaging studies of novel therapeutic agents in rodent models of glioma
MPI FOSTER, F. S
BURNS, Peter N / GOERTZ, David E / KERBEL, Robert S
 $104,977 5 Yr(s)
Sunnybrook Health Sciences Centre
High frequency ultrasound molecular imaging with applications in angiogenesis and preclinical cancer research.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
65
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
MPI HENKELMAN, R. Mark JOSSELYN, Sheena A / LERCH, Jason P / SLED, John G
 $134,667 5 Yr(s)
Hospital for Sick Children (Toronto)
MRI of learning and memory
MPI HOLDSWORTH, David W DUNNING, Cynthia E / NAUDIE, Douglas
 $140,800 5 Yr(s)
University of Western Ontario
Advanced anatomical and dynamic micro- computed tomography for arthritis research
MPI KOZLOWSKI, Piotr MACKAY, Alexander L / TETZLAFF, Wolfram G
 $147,458 3 Yr(s)
University of British Columbia
Development of MRI techniques for animal models of Spinal Cord Injury
LEONG-POI, Howard M
MPI DICK, Alexander J / STEWART, Duncan J
 $132,926 3 Yr(s)
St. Michael's Hospital (Toronto)
Molecular Imaging of Stem Cell Therapy Using Targeted Contrast Ultrasound
MPI LEPAGE, Martin ESCHER, Emanuel / GUÉRIN, Brigitte / NEUGEBAUER, Witold A / PAQUETTE, Benoît
 $133,333 3 Yr(s)
Université de Sherbrooke
Optimization and characterization of novel contrast agents for magnetic resonance imaging allowing the non-invasive detection of matrix metalloproteinases activity in vivo
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
66
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
MPI PETERS, Terence M LEE, Donald H / MIRSATTARI, Seyed M / PARRENT, Andrew G
 $141,416 5 Yr(s)
University of Western Ontario
Image-guided surgery for epilepsy
MPI ZENG, Haishan $78,013 4 Yr(s)
LAM, Stephen
University of British Columbia
B.C. Cancer Research Centre (Vancouver)
Rapid Multi-spectral Imaging of Tissue Physiological and Morphological Changes for Endoscopic Lung Cancer Detection and Localization
NSA AVOLI, Massimo $102,336 5 Yr(s)
McGill University
Montreal Neurological Institute
Cellular mechanisms of epilepsies
NSA LAMBE, Evelyn K $143,605 5 Yr(s)
University of Toronto
Cellular and molecular mechanisms underlying development and plasticity of prefrontal attention circuitry
NSA PITTMAN, Quentin J $126,497 5 Yr(s)
University of Calgary
Plasticity of neuroendocrine and autonomic synapses
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
67
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
NSA ROULEAU, Guy A JULIEN, Jean-Pierre / PARKER, Jodey A / VANDE VELDE, Christine Diane C
 $169,522 5 Yr(s)
Centre Hosp. de l'Université de Montréal (CHUM)
Cellular and biochemical impact of TDP-43 mutants in ALS
NSA STIFANI, Stefano $154,750 5 Yr(s)
McGill University
Basal Telencephalic Limbic System Development
NSA STRONG, Michael J $171,530 3 Yr(s)
University of Western Ontario
Robarts Research Institute - U.W.O. (London, Ont.)
The role of TDP-43 in regulating NFL mRNA metabolism.
NSA WANG, Lu-Yang $157,229 5 Yr(s)
Hospital for Sick Children (Toronto)
Spatial and temporal plasticity of neurotransmitter release at a developing central synapse
NSA ZOCHODNE, Douglas W $111,945 5 Yr(s)
University of Calgary
Diabetes, neuron degeneration and insulin signaling
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
68
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
NSB CAYOUETTE, Michel $131,595 3 Yr(s)
Institut de recherches cliniques de Montréal
Mechanisms of cell-fate choice in the developing mammalian retina
NSB CLOUTIER, Jean-Francois $154,376 5 Yr(s)
McGill University
Montreal Neurological Institute
Molecular mechanisms of sensory systems development
NSB JULIEN, Jean-Pierre $133,300 5 Yr(s)
Université Laval
Centre hospitalier de l'Université Laval (Québec)
The role of inflammation in pathogenesis and immunotherapy of ALS
NSB PRAT, Alexandre ARBOUR, Nathalie $110,940 5 Yr(s)
Centre Hosp. de l'Université de Montréal (CHUM)
Novel Adhesion Molecules of the Blood-Brain Barrier Regulating CNS Inflammation
NSB ROSKAMS, Angela J $148,178 5 Yr(s)
University of British Columbia
A role for SPARC in the Regulation of CNS Repair
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
69
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
NSB STELLWAGEN, David $147,738 5 Yr(s)
The Research Institute of the McGill University Health Centre
The role of TNFalpha in synaptic plasticity and during neurodegeneration
NSB THOMPSON, Roger J $117,436 5 Yr(s)
University of Calgary
Pannexin-1 Hemichannel Activation in Neurons.
NSB TYMIANSKI, Michael $179,793 5 Yr(s)
University Health Network (Toronto)
Toronto Western Hospital
Role of TRPM Channels in Ischemic Brain Damage
NSB WANG, Yu Tian $204,293 5 Yr(s)
University of British Columbia
Regulation of postsynaptic expression and function of GABA-A receptors
NUT ALLARD, Johane P GUINDI, Maha / MA, David W / MCGILVRAY, Ian D / THERAPONDOS, George
 $118,261 3 Yr(s)
University Health Network (Toronto)
Non-alcoholic fatty liver disease: Role of fatty acid composition and gene expression
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
70
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
NUT BARACOS, Vickie E DIELEMAN, Levinus A / FIELD, Catherine J / SAWYER, Michael B
 $104,791 3 Yr(s)
University of Alberta
Nutritional modulation of antineoplastic therapy
NUT EL-SOHEMY, Ahmed $60,000 3 Yr(s)
University of Toronto
Genetic modifiers of coffee intake on cardiovascular disease risk
NUT GOUGEON, Réjeanne D MARLISS, Errol B / MORAIS, José A
 $164,736 5 Yr(s)
McGill University
Royal Victoria Hospital (Montreal)
Insulin sensitivity of protein in Type 2 Diabetes Mellitus
NUT KEITH, Mary E LEONG-POI, Howard M / STEWART, Duncan J
 $118,783 3 Yr(s)
St. Michael's Hospital (Toronto)
Defining the effects of B vitamins on the endogenous angiogenic response to ischemia
NUT MA, David W $108,619 3 Yr(s)
University of Guelph
Role of caveolae and fatty acids in pubertal mammary gland development and carcinogenesis
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
71
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
NUT ROZEN, Rima $137,067 5 Yr(s)
The Research Institute of the McGill University Health Centre
Low dietary folate and colorectal carcinogenesis
NUT WARD, Wendy E $93,771 3 Yr(s)
University of Toronto
Neonatal isoflavone exposure and long term programming of bone metabolism
PLC DAVISON, Sara
KLARENBACH, Scott / TONELLI, Marcello A
 $79,676 4 Yr(s)
University of Alberta
Characterizing the Dying Experience and End- of-Life Care Needs for Patients with Chronic Kidney Disease
PLC DUGGLEBY, Wendy
COOPER, Dan / HAMPTON, Mary R / HOLTSLANDER, Lorraine F / MACLEAN, Michael / POPKIN, David R / THOMAS-MACLEAN, Roanne Leigh / WILSON, Donna M
 $81,573 3 Yr(s)
WILLIAMS, Allison M
University of Saskatchewan
Living with Hope: Developing a Psychosocial Supportive Program for Rural Older Women Caregivers of Spouses with Advanced Cancer
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
72
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
POP DOSMAN, James A CHEN, Yue / PITBLADO, John R / RENNIE, Donna Carole
 $283,785 6 Yr(s)
GORDON, John R
PAHWA, Punam
University of Saskatchewan
Saskatchewan Rural Health Study
POP GOLDBERG, Mark S BROPHY, James M / BURNETT, Richard T / ESSEBAG, Vidal / HADJIS, Tom A / MAYO, Nancy E / MILLER, Sydney B / TALAJIC, Mario
 $178,922 5 Yr(s)
KHAIRY, Paul
McGill University
The Research Institute of the McGill University Health Centre
A longitudinal study to identify factors that trigger ventricular tachyarrythmias among persons with implanted cardioverter defibrillators
POP LAVOIE, Kim ARSENAULT, André / BACON, Simon L / DUPUIS, Jocelyn / PILOTE, Louise / VADEBONCOEUR, Alain
 $85,235 4 Yr(s)
6 Mths
Montreal Heart Institute
Improving prediction of cardiovascular morbidity and mortality in men and women using a new nuclear imaging technique designed to assess endothelial function by vascular reactivity
POP MCINTYRE, Lynn CURTIS, Lori J / EMERY, John H / KIRKPATRICK, Sharon / MCLAREN, Lindsay / TARASUK, Valerie S / WOLFSON, Michael C
 $124,290 3 Yr(s)
University of Calgary
Policy Drivers of Food Insecurity in Canada, 1994-2006
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
73
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
POP MOORE, David M COUTINHO, Alex G / HOGG, Robert S / KING, Rachel L / MILLS, Edward J / NABIRYO, Christine
 $139,142 3 Yr(s)
MONTANER, Julio S
University of British Columbia
Antiretroviral therapy as an additional HIV prevention tool for sero-discordant couples in Uganda
POP PUNTHAKEE, Zubin HILL, Stephen A / MCQUEEN, Matthew J
 $71,118 3 Yr(s)
DEVEREAUX, Philip J
GERSTEIN, Hertzel C
McMaster University
Glucose as a predictor of Vascular events In noncardiac Surgery patIents cOhort evaluatioN (GlucoVISION)
POP WANG, Jianli CURRIE, Shawn R / PATTEN, Scott B / SAREEN, Jitender / SCHMITZ, Norbert
 $63,345 3 Yr(s)
University of Calgary
Perceived needs and utilization of workplace mental health accommodations among workers with depressive and anxiety disorders
POP YUSUF, Salim GILMORE, Anna B / MCKEE, Martin / POGUE, Janice M / SANKARANARAYANAN, Subramanian V / TEO, Koon K
 $143,385 2 Yr(s)
CHOW, Clara K
McMaster University
Upstream Determinants of Smoking in Low, Middle and High Income Countries participating in PURE (Prospective Urban Rural Epidemiologic study)
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
74
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
PS AUCLAIR, Karine MITTERMAIER, Anthony K $150,393 3 Yr(s)
McGill University
Design of inhibitors of the resistance-causing aminoglycoside N-6'-acetyltransferase
PS BURT, Helen M BALLY, Marcel B / WATERHOUSE, Dawn N
 $126,909 4 Yr(s)
University of British Columbia
Inhibition of drug efflux transport proteins by amphiphilic diblock copolymers
PS GAUDREAULT, René C
PETITCLERC, Eric $128,742 5 Yr(s)
Université Laval
Hôpital Saint-François d'Assise (Québec)
Aryl 2-chloroethylureas as thioredoxin and cellular redox homeostasis inhibitors: Structure- activity relationships and mechanisms of anticancer activity
PS HASINOFF, Brian B $129,961 3 Yr(s)
University of Manitoba
Structure-based targeting of topoisomerase II
PS KIM, Richard B DRESSER, George K / TIRONA, Rommel G
 $159,771 5 Yr(s)
University of Western Ontario
Hepatic Organic Anion Transporting Polypeptide (OATP) drug uptake transporters as determinants of drug disposition
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
75
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
PS MASSEY, Thomas E $163,452 5 Yr(s)
Queen's University (Kingston, Ontario)
Biotransformation and Molecular Toxicity of Pulmonary Carcinogens
PS MAYSINGER, Dusica $99,674 3 Yr(s)
McGill University
NANOMEDICINES: A Non-Invasive Approach to Neural Sensing, Imaging, and Chaperoning in the Compromised Nervous System
PS PANG, Kim-Ching S $120,717 5 Yr(s)
University of Toronto
Interplay of Transporters, Enzymes, and Nuclear Receptors in First-Pass Drug Absorption
PS SCHILLER, Peter W $135,814 5 Yr(s)
Institut de recherches cliniques de Montréal
Neuropeptides and peptidomimetics as parmacological tools and potential drugs
PS THOMPSON, Alison $113,449 3 Yr(s)
Dalhousie University (Nova Scotia)
Design, Synthesis and Evaluation of Prodigiosin Analogues as Chemotherapeutic Agents
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
76
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
PS XIANG, Jim (Jianhua) $123,201 4 Yr(s)
University of Saskatchewan
CD4+ T-Cell vaccine capable of breaking immune tolerance, A novel anti-cancer pharmaceutical.
PSB AVISON, William R DAVIES, Lorraine E / FORD-GILBOE, Marilyn V / SEALY, Pat / SPEECHLEY, Kathy N
 $144,580 5 Yr(s)
University of Western Ontario
A Life Course Analysis of Family Structure, Stress, and Mothers' Mental Health: Setting the Stage for a Prospective Study of Families
PSB BERGERON, Sophie BINIK, Yitzchak Irving M / DUPUIS, Marie-Josée / KHALIFE, Samir
 $59,988 4 Yr(s)
Université du Québec à Montréal
Dyadic predictors of pain and related sexual impairment in women with vulvodynia: A prospective investigation
PSB GUAY, Stéphane
BOYER, Richard / MARCHAND, André
 $67,273 5 Yr(s)
Hôpital Louis H. Lafontaine (Montréal)
Centre de recherche Fernand-Seguin de l'Hôpital Louis H.- Lafontaine (Mtl)
Étude prospective sur l'impact psychologique et social de la victimisation criminelle avec violence
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
77
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
PSB MACDONALD, Scott A CALLAGHAN, Russell C / GUIMARAES BORGES, Guilherme L / ROTH, Eric / SALMON, Amy L / STOCKWELL, Tim R / WELLS, Samantha L
 $49,562 4 Yr(s)
University of Victoria (British Columbia)
Patterns and consequences of cocaine and alcohol use for substance abuse treatment clients
PSB MILLER, Gregory E KOBOR, Michael S / MA, Roy / WROSCH, Carsten
 $189,406 5 Yr(s)
University of British Columbia
The Psychobiology of Caregiving for a Spouse with Cancer
PSB MISHARA, Brian L ALDERSON, Marie / CHAGNON, Francois / DAIGLE, Marc S / GREENFIELD, Brian J / HENRY, Melissa / LESAGE, Alain D / RAYMOND, Sylvaine / SOARES, Angelo / ST-LAURENT, Danielle / TOUSIGNANT, Michel
 $98,788 3 Yr(s)
Université du Québec à Montréal
Suicide, santé mentale et milieu de travail: Étude des conséquences du suicide d'un travailleur sur la santé mentale des collègues et sur le climat de travail
PSB PATTEN, Scott B ELIASZIW, Michael / MARRA, Carlo A
 $70,003 3 Yr(s)
University of Calgary
Major Depression and Health Status Changes
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
78
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
PSB SABISTON, Catherine M O'LOUGHLIN, Jennifer L / WROSCH, Carsten
 $144,118 3 Yr(s)
McGill University
Physical activity among breast cancer survivors: Understanding the impact on biological risk factors and psychological health over time.
PSB SAREEN, Jitender ASMUNDSON, Gordon J / COX, Brian J / WANG, Jianli
 $60,000 2 Yr(s)
University of Manitoba
Work Stress and Childhood Adversity in relation to Mental Disorders and Suicidality Among Canadian Soldiers: Analysis of a large Population-Based Sample
PSB STEVENS, Bonnie J ASZTALOS, Elizabeth V / BEYENE, Joseph / HOWLETT, Alexandra A / JOHNSTON, Celeste / MCNAMARA, Patrick J / O'BRIEN, Karel / PILLAI RIDDELL, Rebecca Rita E
 $184,734 4 Yr(s)
GIBBINS, Sharyn A
MCGRATH, Patrick J
Hospital for Sick Children (Toronto)
Pain in Infants at risk for Neurological Impairment: A Program of Research: Phase 3
PT GOBEIL, Fernand J $104,038 4 Yr(s)
Université de Sherbrooke
Probing signalling and biological outcomes of nuclear bradykinin receptors.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
79
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
PT GUILLEMETTE, Gaétan ESCHER, Emanuel / LAVIGNE, Pierre / LEDUC, Richard
 $131,597 5 Yr(s)
Université de Sherbrooke
Bases moléculaires de la fonction du récepteur AT1 de l'angiotensine II
PT HAMMOND, James R $100,843 3 Yr(s)
University of Western Ontario
Structure-Function Analysis of Drug Interactions with Nucleoside Transporters
PT MA, Weiya
$94,510 3 Yr(s)
Douglas Hospital Research Centre (Verdun, Québec)
McGill University
Peripherally derived inflammatory mediators and chronic pain
PT OKEY, Allan B BOUTROS, Paul C $131,064 3 Yr(s)
University of Toronto
Dioxin toxicity: gene expression in a resistant rat model
PT PARKINSON, Fiona E ANDERSON, Christopher M $119,841 5 Yr(s)
ALBENSI, Benedict C
University of Manitoba
Regulation of brain adenosine levels by ecto- enzymes and membrane transporters.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
80
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
PT POWELL, William S $143,165 5 Yr(s)
McGill University
Biosynthesis and role of eicosanoids in inflammation
PT THORIN, Eric $149,289 5 Yr(s)
Montreal Heart Institute
Ageing of the vascular endothelium
PUB CIBERE, Jolanda ESDAILE, John M / KOPEC, Jacek A / NICOLAOU, Savvakis / SINGER, Joel / THORNE, Anona E / WONG, Hubert H
 $161,295 3 Yr(s)
The Arthritis Research Centre of Canada
Vancouver Longitudinal Study of Early Knee Osteoarthritis
PUB DENDUKURI, Nandini
$60,992 3 Yr(s)
PAI, Madhukar
McGill University
Novel statistical methods for Tuberculosis diagnostic studies
ERNST, Pierre-Paul
PUB BRASSARD, Paul / DELANEY, Joseph Austin C / MIKAELOFF, Yann / SUISSA, Samy
 $71,327 2 Yr(s)
McGill University
Adverse effects of inhaled corticosteroids in patients with respiratory disease.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
81
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
PUB KAPLAN, Gilaad G HILSDEN, Robert J / NGUYEN, Geoffrey C / WHEELER, Amanda J
 $96,696 2 Yr(s)
VILLENEUVE, Paul J
University of Calgary
The effect of outdoor air pollution on the incidence and prognosis of the inflammatory bowel diseases in Canada
PUB LOUCKS, Eric B ABRAHAMOWICZ, Michal M / ENGERT, James C / HARPER, Samuel / LYNCH, John W / MEANEY, Michael J / PILOTE, Louise
 $62,622 3 Yr(s)
Douglas Hospital Research Centre (Verdun, Québec)
Life Course Socioeconomic Position, Type II Diabetes, and Obesity: Potential Interactions with Genetic Polymorphisms
PUB PAI, Madhukar DALEY, Peter / DENDUKURI, Nandini / DHEDA, Keertan / GREENAWAY, Christina A / MENZIES, Richard
 $100,626 3 Yr(s)
The Research Institute of the McGill University Health Centre
Innovative approaches for diagnosing tuberculosis in the era of HIV
RS DALEY, Denise $135,397 3 Yr(s)
University of British Columbia
St. Paul's Hospital, Vancouver
The Genetics of Asthma, Atopy and Allergic Diseases
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
82
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
RS GAULDIE, Jack $149,412 5 Yr(s)
McMaster University
Pathogenic Mechanisms in Persistent Pulmonary Fibrosis
RS GRANDVAUX, Nathalie $118,649 5 Yr(s)
Centre Hosp. de l'Université de Montréal (CHUM)
Redox regulation of the RSV-induced proinflammatory response in airway epithelial cells.
RS GREER, John J
$134,934 5 Yr(s)
University of Alberta
Ampakine Therapy to Alleviate Respiratory Depression
RS LIU, Mingyao $142,782 5 Yr(s)
University Health Network (Toronto)
Signal crosstalk in lung injury and repair
RS MCCUSKER, Christine T $94,597 3 Yr(s)
The Research Institute of the McGill University Health Centre
Meakins Christie Labs (Québec)
Mechanisms of tolerance induction through neonatal exposure to environmental antigens. Prevention of asthma and allergic rhinitis
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
83
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
RS MOQBEL, Redwan LACY, Paige $154,500 5 Yr(s)
University of Alberta
Intracellular Mechanisms in Eosinophil Exocytosis: Contribution to the Development of Airway Inflammation.
RS SERIES, Frédéric H SIMILOWSKI, Thomas $120,310 5 Yr(s)
Université Laval
Institut universitaire de cardiologie et pneumologie de Québec
Pathophysiology of sleep disordered breathing
RS THOMAS, David Y CARLILE, Graeme W / HANRAHAN, John W / ROBERT, Renaud S
 $114,036 5 Yr(s)
McGill University
Mechanisms of correction of deltaF508CFTR
SDA GIGNAC, Monique A BACKMAN, Catherine L / BADLEY, Elizabeth M / DAVIS, Aileen M / LACAILLE, Diane V
 $104,634 2 Yr(s)
University Health Network (Toronto)
Measuring What Matters in Life: Patterns of Role Participation in Arthritis
SDA GOTTLIEB, Benjamin H MAITLAND, Scott B / MEEGAN, Daniel / SPRIET, Lawrence L
 $107,084 3 Yr(s)
University of Guelph
Contribution of Volunteer Service to the Physical Fitness and Cognitive Functioning of Older Adults: A Prospective, Comparison Study
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
84
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
SDA SHATENSTEIN, Bryna GAUVIN, Lise / KELLER, Heather H / PAYETTE, Hélène / RICHARD, Lucie
 $56,877 1 Yr(s)
Institut universitaire de gériatrie de Montréal
The impact of personal characteristics and social factors on food choices and adaptive strategies for maintaining diet quality among community-dwelling older adults
VVP ARCHAMBAULT, Jacques $120,701 5 Yr(s)
Institut de recherches cliniques de Montréal
Functions and regulation of the papillomavirus E1 and E2 proteins in the viral life cycle
VVP BARRY, Marie M $122,077 5 Yr(s)
University of Alberta
Poxvirus Control of Ubiquitination
VVP COOMBS, Kevin M
$143,507 5 Yr(s)
University of Manitoba
Structure/Function of Reovirus Core: Host Proteomic Perturbations
VVP FLAMAND, Louis $118,637 5 Yr(s)
Université Laval
Centre hospitalier de l'Université Laval (Québec)
Shutting down the innate immune response: Mechanisms and strategies utilized by human herpesvirus 6 to persist within the infected host.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
85
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
VVP KAUL, Rupert GELMON, Lawrence J / KIMANI, Joshua
 $121,896 3 Yr(s)
University of Toronto
Antiretroviral rollout in a "core transmission" group of female sex workers: impact on mucosal co-infections and predictors of HIV transmission.
VVP LAMARRE, Alain $128,290 3 Yr(s)
INRS - (Québec, QC)
INRS-Institut Armand-Frappier (Laval)
Role of natural antibodies in promoting acquired immune responses to hepatitis C virus.
VVP LANGLOIS, Marc-Andre $121,805 5 Yr(s)
Université Laval
Centre hospitalier de l'Université Laval (Québec)
Molecular and cellular mechanisms involved in APOBEC3G-mediated innate immunity to HIV infection
VVP LECLERC, Denis LAMARRE, Alain / LAPOINTE, Réjean
 $118,736 5 Yr(s)
Université Laval
Centre hospitalier de l'Université Laval (Québec)
Characterization and improvement of the intrinsic adjuvant properties of papaya mosaic virus-like particles: An innovative vaccine platform.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
86
PRC **
 Principal Investigators
Institution Paid
Research Institution*
Title
Co-Applicant(s), Associate(s)
 Average Annual Operating Amount
 Equipment Term Status
VVP SADOWSKI, Ivan J $118,374 3 Yr(s)
University of British Columbia
Ras-responsive elements in HIV-1 replication and AIDS pathogenesis
VVP SATO, Sachiko TREMBLAY, Michel J $103,384 3 Yr(s)
Université Laval
Centre hospitalier de l'Université Laval (Québec)
Biochemical, cellular and molecular studies to dissect the contribution of the soluble host carbohydrate binding proteins to HIV-1 pathogenesis
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
87
Peer Review Committees
PRC Name
ABH Aboriginal Peoples' Health
BCA Biological and Clinical Aspects of Aging
BMA Biochemistry & Molecular Biology - A
BMB Biochemistry & Molecular Biology - B
BME Biomedical Engineering
BSA Behavioural Sciences - A
BSB Behavioural Sciences - B
BSC Behavioural Sciences - C
CBM Cell Biology & Mechanisms of Disease
CBT Cancer Biology & Therapeutics
CHI Children's Health
CIA Clinical Investigation - A
CIB Clinical Investigation - B
CP Cell Physiology
CPT Cancer Progression & Therapeutics
CSA Cardiovascular System - A
CSB Cardiovascular System - B
CSC Cardiovascular System - C
DEV Developmental Biology
DS Dental Sciences
E Endocrinology
ELH Health Ethics, Law & Humanities
EM Experimental Medicine
G Genetics
GMX Genomics
GSH Gender, Sex & Health
HPM Health Policy & Systems Management Research
HSI Health Services Evaluation and Interventions Research - B
HSR Health Services Evaluation & Interventions Research - A
IT Immunology and Transplantation
KTE Knowledge Translation & Exchange
M Metabolism
MCC Molecular & Cellular Biology of Cancer
MI Microbiology & Infectious Diseases
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
88
MOV Movement & Exercise
MPI Medical Physics & Imaging
NSA Neurosciences - A
NSB Neurosciences - B
NUT Nutrition, Food & Health
PLC Palliative & End of Life Care
POP Public, Community & Population Health - A
PS Pharmaceutical Sciences
PSB Psychosocial, Sociocultural & Behavioural Determinants of Health - A
PT Pharmacology & Toxicology
PUB Public, Community and Population Health - B
RS Respiratory System
SDA Social Dimensions in Aging
VVP Virology & Viral Pathogenesis
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
89