Results of the 03/03/2008 200803MOP Operating Grant Competition
Updated : 18/03/2009
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
AHMED, Sara BARTLETT, Susan J / ERNST, Pierre-Paul / GRAD, Roland M / PARÉ, Guy / PERREAULT, Robert / PINSONNEAULT, Alain / TAYLOR, Laurel K
 $69,898 2 Yr(s)
6 Mths
 KTE
McGill University
Facilitating patient self-management in chronic disease: Integrating electronic personal health records and ongoing communication into a web- based self-management tool
AKIMENKO, Marie-Andrée $138,280 5 Yr(s) DEV
Ottawa Health Research Institute
Control mechanisms of fin regeneration in zebrafish
ALDA, Martin $225,467 5 Yr(s) BSB
MACQUEEN, Glenda M
ROULEAU, Guy A
TURECKI, Gustavo X
YOUNG, L. T
Dalhousie University (Nova Scotia)
Phenotypic and molecular heterogeneity of bipolar disorder
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
1
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
ALLARD, Johane P GUINDI, Maha / MA, David W / MCGILVRAY, Ian D / THERAPONDOS, George
 $118,261 3 Yr(s) NUT
University Health Network (Toronto)
Non-alcoholic fatty liver disease: Role of fatty acid composition and gene expression
AMIR, Shimon $146,647 5 Yr(s) BSA
Concordia University (Montreal, Quebec)
Regulation and function of circadian clocks in the limbic forebrain
ANTONIOU, John IATRIDIS, James / MWALE, Fackson
 $81,246 3 Yr(s) CIB
Jewish General Hospital (Montreal)
Lady Davis Institute for Medical Research (Mtl)
Quantitative magnetic resonance imaging as a diagnostic tool of intervertebral disc matrix composition and integrity
ARCHAMBAULT, Jacques $120,701 5 Yr(s) VVP
Institut de recherches cliniques de Montréal
Functions and regulation of the papillomavirus E1 and E2 proteins in the viral life cycle
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
2
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
ARNOLD, Donald M CROWTHER, Mark A / KELTON, John G / LARCHE, Mark / SNIDER, Denis P
 $109,229 2 Yr(s) IT
McMaster University
The effect of rituximab on the humoral immune response to S. pneumoniae and H. influenzae type b vaccines in patients with immune thrombocytopenic purpura
AUCLAIR, Karine MITTERMAIER, Anthony K
 $150,393 3 Yr(s) PS
McGill University
Design of inhibitors of the resistance-causing aminoglycoside N-6'-acetyltransferase
AVISON, William R DAVIES, Lorraine E / FORD-GILBOE, Marilyn V / SEALY, Pat / SPEECHLEY, Kathy N
 $144,580 5 Yr(s) PSB
University of Western Ontario
A Life Course Analysis of Family Structure, Stress, and Mothers' Mental Health: Setting the Stage for a Prospective Study of Families
AVOLI, Massimo $102,336 5 Yr(s) NSA
McGill University
Montreal Neurological Institute
Cellular mechanisms of epilepsies
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
3
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
BACKX, Peter H $146,346 5 Yr(s) CSA
University Health Network (Toronto)
Mechanisms for (subcellular) regulation of cAMP in normal and diseased heart
BAILLARGEON, Raymond H KEENAN, Kathryn / LEFEBVRE, Francine
 $60,000 2 Yr(s) GSH
University of Ottawa
The Origins of Gender Differences in Disruptive Behavior Problems II
BALLY, Marcel B APARICIO, Samuel J / JONES, Steven / LASKIN, Janessa J / MARRA, Marco A
 $159,178 3 Yr(s) CPT
University of British Columbia
BC Cancer Agency (Vancouver, BC)
SynTarg Discovery Program: Use of a Genome Wide siRNA Screen To Identify Targets that will Enhance Platinum-Containing Chemotherapy when used in First Line Therapy of Non-Small Cell Lung Cancer
BARACOS, Vickie E DIELEMAN, Levinus A / FIELD, Catherine J / SAWYER, Michael B
 $104,791 3 Yr(s) NUT
University of Alberta
Nutritional modulation of antineoplastic therapy
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
4
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
BARR, Cathy L KERR, Elizabeth N / LOVETT, Maureen W
 $200,665 5 Yr(s) BSB
University Health Network (Toronto)
Toronto Western Research Institute (Toronto)
Genetics of Reading Disabilities
BARRY, Marie M $122,077 5 Yr(s) VVP
University of Alberta
Poxvirus Control of Ubiquitination
BAUCH, Christopher T ANONYCHUK, Andrea / COLGAN, Terence J / HOWLETT, Robbi (Roberta) / JOHN- BAPTISTE, Ava A / SANDER, Beate H
 $76,046 3 Yr(s) HSR
GILCA, Vladimir
KRAHN, Murray D
MAI, Verna
MCLACHLIN, Catherine (Meg) M
PHAM, Ba'
University of Guelph
Cervical cancer screening in the era of HPV vaccination: using mathematical and economic models to guide screening policy
BAYOUMI, Ahmed M ANTONIOU, Tony / HOCH, Jeffrey S / PARK-WYLLIE, Laura / STRIKE, Carol J / TABACK, Nathan A
 $130,723 2 Yr(s) HSR
St. Michael's Hospital (Toronto)
Preference Measures for HIV Antiretroviral Decision Making
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
5
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
BEDELL, Barry J EVANS, Alan C / PIKE, G. Bruce / ROSA-NETO, Pedro / STANIMIROVIC, Danica
 $158,224 4 Yr(s) MPI
McGill University
Montreal Neurological Institute
Multi-parametric imaging studies of novel therapeutic agents in rodent models of glioma
BELL, Chaim M BIERMAN, Arlene S / BRONSKILL, Susan E / ETCHELLS, Edward E / FERNANDES, Olavo A / MAMDANI, Muhammad / ROCHON, Paula A / URBACH, David R
 $63,057 3 Yr(s) HSR
St. Michael's Hospital (Toronto)
Unintentional discontinuation of chronic medications for seniors in long-term care facilities: An evaluation of a medication reconciliation and quality improvement strategy
BELL, Scott M MUHAJARINE, Nazeem / RAMSDEN, Vivian R / WILSON, Kathleen J
 $98,414 3 Yr(s) HSI
University of Saskatchewan
Examining Access to Health Care at the Neighbourhood Level
BENNETT, Steffany A BAETZ, Kristin K $107,070 5 Yr(s) CBM
FIGEYS, Daniel
University of Ottawa
Lipidomics of neurodegenerative disease: A systems and cell biology approach to reverse neuronal vulnerability
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
6
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
BERGER, Stuart A $104,799 3 Yr(s) CPT
University Health Network (Toronto)
Calpain and calpastatin in leukemia
BERGERON, John J NILSSON, Tommy J $264,865 5 Yr(s) CBM
McGill University
The Molecular Cytology of Membrane Dynamics
BERGERON, Sophie BINIK, Yitzchak Irving M / DUPUIS, Marie-Josée / KHALIFE, Samir
 $59,988 4 Yr(s) PSB
Université du Québec à Montréal
Dyadic predictors of pain and related sexual impairment in women with vulvodynia: A prospective investigation
BERMAN, Helene A CLASSEN, Catherine C / LANIUS, Ruth A / MACARTHUR-EVANS, Marilyn K / RODGER, Susan C / ROSS, Lori E
 $73,920 3 Yr(s) GSH
MASON, Robin A
University of Western Ontario
Embodied Trauma: The Influence of Past Trauma on Women During the Transition to Motherhood
BERNARD, Daniel J BOERBOOM, Derek Theodoor
 $159,619 5 Yr(s) GSH
McGill University
Transcriptional regulation of follicle stimulating hormone synthesis
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
7
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
BHATIA, Mickie $159,893 5 Yr(s) DEV
McMaster University
Characterization of the human embryonic stem cell niche
BLACK, Sandra E CALDWELL, Curtis B / GAO, Fuqiang / HERRMANN, Nathan / KISS, Alexander J / LANCTOT, Krista L / LOBAUGH, Nancy J / MASELLIS, Mario / MCILROY, William E / ROGAEVA, Ekaterina / STEFANOVIC, Bojana / STUSS, Donald T / SWARTZ, Richard
 $282,211 5 Yr(s) BSB
Sunnybrook Health Sciences Centre
In Vivo Brain Mapping in the Dementias: A Longitudinal Brain-Behaviour Study With a Focus on interactions of Alzheimer's and Cerebrovascular Disease
BLEACKLEY, Robert C $178,948 5 Yr(s) IT
University of Alberta
Lymphocyte Proteinases
BOHBOT, Véronique DAGHER, Alain $50,005 2 Yr(s) BCA
Douglas Hospital Research Centre (Verdun, Québec)
MRI and Virtual Navigational Strategies in Parkinson's Disease
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
8
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
BONNET, Sébastien $118,500 5 Yr(s) CSC
University of Alberta
Experimental therapies for vascular remodeling diseases
BORASTON, Alisdair B SMITH, Steven P $169,977 5 Yr(s) BMA
University of Victoria (British Columbia)
Carbohydrate-recognition in bacterial pathogenesis: structural and functional analysis of virulence-associated Clostridium perfringens enzymes.
BOUDREAU, François $138,284 3 Yr(s) EM
Université de Sherbrooke
Functional role of specific transcriptional regulators during intestinal epithelial development and maintenance
BRAND, Marjorie C $149,655 3 Yr(s) CBT
Ottawa Health Research Institute
Epigenetic Regulation of Erythropoiesis by the MLL Family of Proto-oncogenes
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
9
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
BRESSMANN, Tim KULKARNI, Gajanan V $73,178 3 Yr(s) CHI
University of Toronto
Tactile and visual biofeedback in the therapy of compensatory cleft palate articulation
BRINDLEY, David N $144,853 5 Yr(s) CSA
University of Alberta
Control of cardiac fatty acid and glucose metabolism by lipins
BROMME, Dieter CULLIS, Pieter R $111,844 3 Yr(s) CIB
University of British Columbia
Cathepsins K and S inhibition in a rheumatoid arthritis murine model
BROWNSTONE, Robert M $128,731 5 Yr(s) MOV
Dalhousie University (Nova Scotia)
Control of movement: Brain stem control of locomotion
BULMAN, Dennis E WALLACE, Valerie A $170,082 5 Yr(s) G
Ottawa Health Research Institute
Identification of a novel gene for brachydactyly- A1
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
10
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
BURT, Helen M BALLY, Marcel B / WATERHOUSE, Dawn N
 $126,909 4 Yr(s) PS
University of British Columbia
Inhibition of drug efflux transport proteins by amphiphilic diblock copolymers
BUTCHER, Kenneth S BEAULIEU, Christian / EMERY, Derek J / JEERAKATHIL, Thomas J / MAJUMDAR, Sumit R / SHUAIB, Ashfaq
 $88,926 3 Yr(s) CSB
University of Alberta
Cerebral Perfusion and Blood Pressure in Acute Ischemic Stroke.
CANIGGIA, Isabella JURISICOVA, Andrea / POST, Martin
 $151,410 5 Yr(s) CIA
Mount Sinai Hospital (Toronto)
The role of Bcl-2 family members in regulating placental cell fate
CANTOR, James M BARBAREE, Howard E / BLANCHARD, Ray / DICKEY, Robert / GIRARD, Todd A / KLASSEN, Philip E / MIKULIS, David J
 $207,764 5 Yr(s) BSB
Centre for Addiction and Mental Health (Toronto)
Neuroanatomic features specific to pedophilia
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
11
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
CARRENO, Sébastien $132,683 5 Yr(s) CBM
Université de Montréal
Institute for Research in Immunology and Cancer (Montreal, QC)
Role of the Phosphoinositides and Moesin on the Actin/Microtubule crosstalk during cell division.
CARRIER, Julie $101,558 3 Yr(s) EM
Université de Sherbrooke
The role of the estrogen-related receptors alpha (ERRalpha) in the normal and cancerous intestine
CASPER, Robert F BROWN, Theodore J / SHAPIRO, Colin M
 $143,607 3 Yr(s) E
Mount Sinai Hospital (Toronto)
Samuel Lunenfeld Research Institute (Toronto)
Prevention of Circadian Rhythm Disruption by Nocturnal Light Exposure
CAYOUETTE, Michel $131,595 3 Yr(s) NSB
Institut de recherches cliniques de Montréal
Mechanisms of cell-fate choice in the developing mammalian retina
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
12
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
CHALIFOUR, Lorraine E SEBAG, Igal A $108,035 5 Yr(s) CSB
Jewish General Hospital (Montreal)
Steroidal hormone programming in heart.
CHAMBERS, Christine T MCGRATH, Patrick J / MOORE, Christopher / MORRONGIELLO, Barbara A / YANCHAR, Natalie L
 $105,752 5 Yr(s) CHI
IWK Health Centre (Halifax)
Everyday Pains in Young Children
CHARTRAND, Pascal $121,819 4 Yr(s) MCC
Université de Montréal
Telomerase trafficking and maintenance of genome integrity
CHAUDHURI, Avi $123,156 3 Yr(s) BSA
McGill University
Molecular mechanisms of cortical neuroadaptation in primates
CHAUHAN, Balwantray C $161,894 5 Yr(s) CIA
Dalhousie University (Nova Scotia)
Models of Intraocular Pressure and Endothelin- 1 Induced Optic Nerve Damage
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
13
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
CHEN, Wayne S $86,495 3 Yr(s) CBM
University of Calgary
Understanding the Molecular Defects and Treatment of Human Malignant Hyperthermia and Central Core Disease
CHEN, Xing-Zhen $140,382 5 Yr(s) EM
University of Alberta
Polycystin-2: cellular function, regulation and mechanism of renal cyst progression
CHERTKOW, Howard M EVANS, Alan C / THIEL, Alexander / WHATMOUGH, Christine E
 $149,843 3 Yr(s) BSB
Jewish General Hospital (Montreal)
Lady Davis Institute for Medical Research (Mtl)
Diagnosis, localization, and treatment of semantic memory impairment in Alzheimer's Disease
CHTEINBERG, Serguei V $108,876 5 Yr(s) BMB
Université de Montréal
Exploring the mechanisms of alternative reading of genetic code
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
14
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
CHUA, Gordon $129,473 5 Yr(s) GMX
University of Calgary
Deciphering pathways of transcriptional regulation in Schizosaccharomyces pombe
CIBERE, Jolanda ESDAILE, John M / KOPEC, Jacek A / NICOLAOU, Savvakis / SINGER, Joel / THORNE, Anona E / WONG, Hubert H
 $161,295 3 Yr(s) PUB
The Arthritis Research Centre of Canada
Vancouver Longitudinal Study of Early Knee Osteoarthritis
CLARK, Alexander M CHAN, Michael C / EZEKOWITZ, Justin A / KASZA, Leslie A / MCALISTER, Finlay A / STRAIN, Laurel A / TSUYUKI, Ross T
 $88,802 2 Yr(s) HSI
University of Alberta
Improving heart failure outcomes in rural communities: Moving from understanding to practice change
CLOUTIER, Jean-Francois $154,376 5 Yr(s) NSB
McGill University
Montreal Neurological Institute
Molecular mechanisms of sensory systems development
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
15
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
COOMBS, Kevin M $143,507 5 Yr(s) VVP
University of Manitoba
Structure/Function of Reovirus Core: Host Proteomic Perturbations
COUSINEAU, Benoit OLIVIER, Martin $130,464 3 Yr(s) MI
McGill University
Development of a new generation of live vaccines using Lactococcus lactis
COUTTS, Shelagh B DEMCHUK, Andrew M / ELIASZIW, Michael / FRAYNE, Richard / GOYAL, Mayank / HILL, Michael D
 $122,798 3 Yr(s) CSC
University of Calgary
CT And MRI in the Triage of TIA and minor Cerebrovascular events to identify High risk patients. (CATCH)
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
16
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
COWARD, Harold G AGUPIO, Godfrey / ATTIG, Thomas W / BRUCE, W. A / CLARK, David / CLOUSTON, Joyce / DAVIES, Elizabeth M / FLORIDA, Robert E / HADLEY, Michael L / HUI, Edwin C / KAUFERT, Joseph M / NAYAR, Kamala E / RAMBACHAN, Anantanand / RAVVIN, Norman / SOSKICE, Janet C / WAUGH, Earle H
 $51,641 3 Yr(s) ELH
STAJDUHAR, Kelli I
University of Victoria (British Columbia)
Religious Requirements for a "Good Death" in Hospice Care
CROSS, James C $193,149 5 Yr(s) E
University of Calgary
Biology of Trophoblast Giant Cells
CROY, Barbara A ADAMS, Michael A / SMITH, Graeme N
 $154,071 5 Yr(s) CIA
Queen's University (Kingston, Ontario)
Evaluation of natural killer cell contributions to the known, elevated risks for maternal and fetal pathologies in diabetic pregnancy
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
17
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
CYBULSKY, Myron I $146,813 5 Yr(s) CSC
University Health Network (Toronto)
Functions of alpha-4 integrins in monocyte emigration.
CYGLER, Mirek M MATTE, Allan M / VALVANO, Miguel A
 $202,526 5 Yr(s) BMA
McGill University
Structure-Function Relationships of Bacterial Polysaccharide Co-Polymerases
DALEY, Denise $135,397 3 Yr(s) RS
University of British Columbia
St. Paul's Hospital, Vancouver
The Genetics of Asthma, Atopy and Allergic Diseases
DAVIDGE, Sandra T $112,150 5 Yr(s) CIA
University of Alberta
Mechanisms for cardiovascular dysfunction in offspring born intrauterine growth restricted
DAVIE, James R $159,827 5 Yr(s) BMB
University of Manitoba
Histone modifications and the epigenetic state of transcribed chromatin
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
18
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
DAVISON, Sara KLARENBACH, Scott / TONELLI, Marcello A
 $79,676 4 Yr(s) PLC
University of Alberta
Characterizing the Dying Experience and End- of-Life Care Needs for Patients with Chronic Kidney Disease
DE BRUM-FERNANDES, Artur J BOIRE, Gilles / PARENT, Jean-Luc
 $92,655 4 Yr(s) CIB
Université de Sherbrooke
Anabolic Properties of Prostaglandin D2 in Human Bone
DENDUKURI, Nandini $60,992 3 Yr(s) PUB
PAI, Madhukar
McGill University
Novel statistical methods for Tuberculosis diagnostic studies
DENG, Alan Y DEBLOIS, Denis $136,265 3 Yr(s) CSB
Centre Hosp. de l'Université de Montréal (CHUM)
Gene discovery for cardiovascular diseases independent of hypertension
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
19
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
DESJARDINS, Michel THIBAULT, Pierre $158,113 5 Yr(s) CBM
Université de Montréal
The phagosome proteome and systems biology: insights into novel phagosome functions
DEVINNEY, Rebekah $116,190 3 Yr(s) MI
University of Calgary
Subversion of host cell signalling by Vibrio parahaemolyticus
DICK, Frederick A $118,193 3 Yr(s) CBT
University of Western Ontario
London Health Sciences Centre (London, Ontario)
Differential control of E2F transcription factors by pRB in normal and cancer cells
DICK, John E $161,250 5 Yr(s) EM
University Health Network (Toronto)
Molecular and cellular characterization of early human hematopoietic lineage determination
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
20
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
DIXON, Elijah BRIEN, Susan E / GHALI, William A / SEIDEL, Judy E / SIMUNOVIC, Marko
 $145,874 3 Yr(s) HSR
University of Calgary
Rates and Waits for Cancer Surgery in Canada: A Mixed Method Assessment
DIXON, Ian Michael C $102,611 5 Yr(s) CSC
University of Manitoba
Regulation of extracellular matrix by myofibroblasts in cardiac hypertrophy and failure
DOSMAN, James A CHEN, Yue / PITBLADO, John R / RENNIE, Donna Carole
 $283,785 6 Yr(s) POP
GORDON, John R
PAHWA, Punam
University of Saskatchewan
Saskatchewan Rural Health Study
DROBETSKY, Elliot A $116,014 3 Yr(s) CBT
Hôpital Maisonneuve-Rosemont (Montréal)
Cell cycle-specific regulation of nucleotide excision repair in human cells
DUBOIS, Claire M $133,673 3 Yr(s) MCC
Université de Sherbrooke
Furin trafficking in cancer invasion and metastasis
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
21
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
DUGGLEBY, Wendy COOPER, Dan / HAMPTON, Mary R / HOLTSLANDER, Lorraine F / MACLEAN, Michael / POPKIN, David R / THOMAS-MACLEAN, Roanne Leigh / WILSON, Donna M
 $81,573 3 Yr(s) PLC
WILLIAMS, Allison M
University of Saskatchewan
Living with Hope: Developing a Psychosocial Supportive Program for Rural Older Women Caregivers of Spouses with Advanced Cancer
DUNN, Stanley D $140,014 5 Yr(s) BMA
University of Western Ontario
Energy Coupling in ATP Synthase
DUROCHER, Daniel $157,689 5 Yr(s) MCC
Mount Sinai Hospital (Toronto)
Deciphering a novel ubiquitin-dependent signaling pathway during the DNA damage response
DUTZ, Jan P $121,076 4 Yr(s) CIB
University of British Columbia
Child and Family Research Institute
Mechanisms of topical TLR activation for the enhancement of immune responses to protein vaccines
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
22
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
EDWARDS, Aled M MAXWELL, Karen L $275,786 5 Yr(s) GMX
University of Toronto
Functional and Structural Genomics of Bacteriophage
EGAN, Sean E ZACKSENHAUS, Eldad $147,008 4 Yr(s) MCC Pending
Hospital for Sick Children (Toronto)
Genetic Analysis of Jagged & Notch1, genes implicated in aggressive breast cancer
EKKER, Marc $176,231 5 Yr(s) DEV
University of Ottawa
Regulation and function of Dlx homeobox genes in the developing forebrain of vertebrates.
EL-GABALAWY, Hani S ELIAS, Brenda D / FERUCCI, Elizabeth D / HITCHON, Carol A / OEN, Kiem G / PESCHKEN, Christine A
 $180,148 5 Yr(s) CIB
University of Manitoba
Early identification of rheumatoid arthritis in First Nations
EL-SOHEMY, Ahmed $60,000 3 Yr(s) NUT
University of Toronto
Genetic modifiers of coffee intake on cardiovascular disease risk
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
23
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
ERNST, Pierre-Paul BRASSARD, Paul / DELANEY, Joseph Austin C / MIKAELOFF, Yann / SUISSA, Samy
 $71,327 2 Yr(s) PUB
McGill University
Adverse effects of inhaled corticosteroids in patients with respiratory disease.
EVANS, Stephen V $123,281 5 Yr(s) BMA
University of Victoria (British Columbia)
Structure-function studies of glycosyltransferases
EVERLING, Stefan $167,327 5 Yr(s) BSC
University of Western Ontario
Robarts Research Institute - U.W.O. (London, Ont.)
Relationship between neural activity and blood oxygenation level-dependent (BOLD) signals in the primate frontal eye fields
FINLAY, Barton B $170,427 5 Yr(s) MI
University of British Columbia
Salmonella Spi 2 Type III effectors that alter host cellular functions
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
24
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
FISET, Céline $170,966 5 Yr(s) CSA
Montreal Heart Institute
Sex hormone-based differences in cardiac electrical activity
FISET, Céline $156,739 5 Yr(s) CP
Montreal Heart Institute
The role of pro-inflammatory cytokines on cardiac repolarization and arrhythmogenesis
FLAMAND, Louis $118,637 5 Yr(s) VVP
Université Laval
Centre hospitalier de l'Université Laval (Québec)
Shutting down the innate immune response: Mechanisms and strategies utilized by human herpesvirus 6 to persist within the infected host.
FLORES, Cecilia $94,239 3 Yr(s) BSA
Douglas Hospital Research Centre (Verdun, Québec)
Role of netrin-1 in the organization and function of dopamine circuitry
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
25
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
FLORESCO, Stanley B $77,204 5 Yr(s) BSA
University of British Columbia
Dopaminergic circuits and risky decision making
FORGET, Robert GAGNON, Isabelle $137,161 5 Yr(s) CHI
FAUBERT, Jocelyn
MCKERRAL, Michelle
Université de Montréal
Visual perception deficits in children after mild traumatic brain injury: psychophysics, electrophysiology and impact on postural stability
FORTIER, Michel A EL-ALFY, Mohamed $114,506 3 Yr(s) CIA
Université Laval
Centre hospitalier de l'Université Laval (Québec)
Genes and proteins of the prostaglandin sythesis and signalling cascades associated with menstrual disorders
FOSTER, F. S BURNS, Peter N / GOERTZ, David E / KERBEL, Robert S
 $104,977 5 Yr(s) MPI
Sunnybrook Health Sciences Centre
High frequency ultrasound molecular imaging with applications in angiogenesis and preclinical cancer research.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
26
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
FOSTER, Leonard J $122,768 5 Yr(s) GMX
University of British Columbia
A global view of host cell manipulation by Salmonella
FRENETTE, Jérôme $98,013 4 Yr(s) MOV
Université Laval
Biological integration of tendon healing:new approaches to understand and accelerate tendon repair
GAISANO, Herbert Y OSBORNE, Lucy R $120,271 5 Yr(s) M
University of Toronto
Distinct insulin exocytotic actions of Syntaxins- 1 and -2
GALDAS, Paul M GREWAL, Sukhdev K / JOHNSON, Joy L / RATNER, Pamela A / WONG, Sabrina
 $55,905 3 Yr(s) GSH
OLIFFE, John L
University of British Columbia
Unpacking the effects of gender and ethnicity on healthcare utilization: The cardiac rehabilitation experiences of Indo-Canadian Men
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
27
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
GALLIN, Warren J SPENCER, Andrew N $120,477 3 Yr(s) CP
University of Alberta
Structure/function analysis of voltage-gated potassium channels
GALLOUZI, Imed $135,584 5 Yr(s) MOV
McGill University
The RNA binding protein HuR is a key player in muscle cell differentiation
GAUDREAULT, René C PETITCLERC, Eric $128,742 5 Yr(s) PS
Université Laval
Hôpital Saint-François d'Assise (Québec)
Aryl 2-chloroethylureas as thioredoxin and cellular redox homeostasis inhibitors: Structure- activity relationships and mechanisms of anticancer activity
GAULDIE, Jack $149,412 5 Yr(s) RS
McMaster University
Pathogenic Mechanisms in Persistent Pulmonary Fibrosis
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
28
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
GIACCA, Adria $122,408 5 Yr(s) M
University of Toronto
Mechanisms of fat-induced hepatic insulin resistance in vivo
GIGNAC, Monique A BACKMAN, Catherine L / BADLEY, Elizabeth M / DAVIS, Aileen M / LACAILLE, Diane V
 $104,634 2 Yr(s) SDA
University Health Network (Toronto)
Measuring What Matters in Life: Patterns of Role Participation in Arthritis
GIROUARD, Hélène $121,688 3 Yr(s) CSC
Université de Montréal
Astrogliosis in Angiotensin II-induced neurovascular uncoupling.
GLOVER, John Newman M $154,097 5 Yr(s) BMA
University of Alberta
Regulation of Bacterial Conjugation
GOBEIL, Fernand J $104,038 4 Yr(s) PT
Université de Sherbrooke
Probing signalling and biological outcomes of nuclear bradykinin receptors.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
29
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
GOLDBERG, Mark S BROPHY, James M / BURNETT, Richard T / ESSEBAG, Vidal / HADJIS, Tom A / MAYO, Nancy E / MILLER, Sydney B / TALAJIC, Mario
 $178,922 5 Yr(s) POP
KHAIRY, Paul
McGill University
The Research Institute of the McGill University Health Centre
A longitudinal study to identify factors that trigger ventricular tachyarrythmias among persons with implanted cardioverter defibrillators
GOLLOB, Michael H $115,982 3 Yr(s) CSB
University of Ottawa
University of Ottawa Heart Institute
Connexin Defects and Mechanistic Insight into the Vunerability of Atrial Fibrillation
GORDON, Karen Ann PAPSIN, Blake C $109,743 4 Yr(s) CHI
Hospital for Sick Children (Toronto)
Processing bilateral electrical input in the developing auditory system
GOTTLIEB, Benjamin H MAITLAND, Scott B / MEEGAN, Daniel / SPRIET, Lawrence L
 $107,084 3 Yr(s) SDA
University of Guelph
Contribution of Volunteer Service to the Physical Fitness and Cognitive Functioning of Older Adults: A Prospective, Comparison Study
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
30
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
GOUGEON, Réjeanne D MARLISS, Errol B / MORAIS, José A
 $164,736 5 Yr(s) NUT
McGill University
Royal Victoria Hospital (Montreal)
Insulin sensitivity of protein in Type 2 Diabetes Mellitus
GRANDVAUX, Nathalie $118,649 5 Yr(s) RS
Centre Hosp. de l'Université de Montréal (CHUM)
Redox regulation of the RSV-induced proinflammatory response in airway epithelial cells.
GRANT, Denis M $119,798 3 Yr(s) GSH
University of Toronto
Gender, genes and risk for arylamine-induced cancers: animal models and mechanisms
GREER, John J $134,934 5 Yr(s) RS
University of Alberta
Ampakine Therapy to Alleviate Respiratory Depression
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
31
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
GRIMSHAW, Jeremy M BROUWERS, Melissa C / DRIEDGER, S. Michelle / ECCLES, Martin P / FRANCIS, Jillian J / GODIN, Gaston / HANNA, Steven E / HUX, Janet E / JOHNSTON, Marie / LEGARE, France / LEMYRE, Louise / POMEY, Marie-Pascale A / SALES, Anne E / ZWARENSTEIN, Merrick F
 $193,768 3 Yr(s) KTE
Ottawa Health Research Institute
Canada Prime Plus: Selecting individual and organizational theories for interventions to change clinical practice
GROOTENDORST, Paul V RACINE, Jeffrey S $106,370 2 Yr(s) HSR
University of Toronto
Assessment of the cost and equity of different catastrophic drug insurance options for Canadians
GRUENHEID, Samantha L $113,468 5 Yr(s) G
McGill University
Genetic dissection of the host response to intestinal infections
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
32
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
GUAY, Stéphane BOYER, Richard / MARCHAND, André
 $67,273 5 Yr(s) PSB
Hôpital Louis H. Lafontaine (Montréal)
Centre de recherche Fernand-Seguin de l'Hôpital Louis H.- Lafontaine (Mtl)
Étude prospective sur l'impact psychologique et social de la victimisation criminelle avec violence
GUÉRIN, Brigitte APARICIO, Samuel J / RUTH, Thomas J
 $108,186 3 Yr(s) CBT
BENARD, Francois
Université de Sherbrooke
Radiolabelled peptides to improve cancer diagnosis by positron emission tomography / Peptides radiomarqués pour améliorer le diagnostic du cancer par tomographie à émission de positron
GUILLEMETTE, Gaétan ESCHER, Emanuel / LAVIGNE, Pierre / LEDUC, Richard
 $131,597 5 Yr(s) PT
Université de Sherbrooke
Bases moléculaires de la fonction du récepteur AT1 de l'angiotensine II
GUITTON, Matthieu J $84,247 5 Yr(s) BSC
Université Laval
Development of new pharmacological therapeutic strategies for long-term tinnitus.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
33
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
GUTTMAN, Julian A $110,037 3 Yr(s) MI
Simon Fraser University (Burnaby, B.C.)
The Role of Endocytic Proteins at Bacteria- Induced Pedestals
HACK, Thomas F DEGNER, Lesley F / GRENIER, Debjani / LATOSINSKY, Steven / RUETHER, Joseph D / WEIR, Lorna
 $112,793 3 Yr(s) KTE
University of Manitoba
Addressing "evidence" and "context" to facilitate the transfer and uptake of consultation recording use in oncology: A knowledge translation implementation study
HAGGERTY, Jeannie L BEAULIEU, Marie- Dominique / HUDON, Catherine / LOIGNON, Christine / PREVILLE, Michel / ROBERGE, Danièle
 $161,880 4 Yr(s) HSR
FORTIN, Martin
Université de Sherbrooke
At the interface of the community and the healthcare system: a longitudinal cohort to study evolving health and the impact of primary healthcare from the patient perspective.
HAMET, Pavel ORLOV, Sergei N / SEDA, Ondrej
 $164,614 5 Yr(s) CSB
Centre Hosp. de l'Université de Montréal (CHUM)
Hypertension at nexus of the thrifty, thirsty and accelerated ageing genotypes: evolution of a complex disease
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
34
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
HAMILTON, Jill K HANLEY, Anthony J / RETNAKARAN, Ravi R / ZINMAN, Bernard
 $88,044 5 Yr(s) CHI
Hospital for Sick Children (Toronto)
Insulin resistance and beta cell dysfunction in early childhood: the role of maternal and infant metabolic risk factors
HAMMOND, James R $100,843 3 Yr(s) PT
University of Western Ontario
Structure-Function Analysis of Drug Interactions with Nucleoside Transporters
HAN, Victor Khin M GUPTA, Madhulika B / IOSEF, Cristiana
 $155,831 5 Yr(s) E
University of Western Ontario
Regulation of Fetal Growth
HARKNESS, Troy A $86,692 3 Yr(s) BCA
University of Saskatchewan
Mechanisms facilitating Anaphase Promoting Complex-dependent lifespan in yeast
HASHER, Lynn GRADY, Cheryl L $98,511 3 Yr(s) BSC
Baycrest Centre for Geriatric Care (Toronto)
Rotman Research Institute (Toronto, Ontario)
Aging and Memory: Behavoural and Neural Underpinnings of Memory Failure
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
35
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
HASINOFF, Brian B $129,961 3 Yr(s) PS
University of Manitoba
Structure-based targeting of topoisomerase II
HEATHCOTE, Elizabeth Jane J SIMINOVITCH, Katherine A
 $245,508 3 Yr(s) EM
University Health Network (Toronto)
Toronto Western Hospital
Molecular Dissection of Primary Biliary Cirrhosis
HEBERT, Marie-Josée BENDAYAN, Moise $116,202 3 Yr(s) EM
Centre Hosp. de l'Université de Montréal (CHUM)
Characterization of non-classical protein secretion pathways of importance in the fibrogenic paracrine response triggered by apoptosis
HEKIMI, Siegfried $104,712 3 Yr(s) DEV
McGill University
Genetics of lipoprotein metabolism in C. elegans
HENKELMAN, R. Mark JOSSELYN, Sheena A / LERCH, Jason P / SLED, John G
 $134,667 5 Yr(s) MPI
Hospital for Sick Children (Toronto)
MRI of learning and memory
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
36
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
HESS, Robert F $178,994 5 Yr(s) BSC
McGill University
The Cortical Sites of Amblyopia and Suppression in Humans
HILDEBRAND, Kevin A HART, David A / SALO, Paul T
 $140,732 3 Yr(s) CIB
University of Calgary
Neuroinflammatory Mechanisms in Joint Contracture Development
HOEMANN, Caroline D EL-GABALAWY, Hani S / RIVARD, Georges E
 $136,497 5 Yr(s) BME
École polytechnique de Montréal
Defining therapeutic inflammation for articular cartilage regeneration
HOLCIK, Martin $136,392 3 Yr(s) BMB
Children's Hospital of Eastern Ontario (Ottawa)
Regulation of internal initiation of translation in cell death and survival
HOLDSWORTH, David W DUNNING, Cynthia E / NAUDIE, Douglas
 $140,800 5 Yr(s) MPI
University of Western Ontario
Advanced anatomical and dynamic micro- computed tomography for arthritis research
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
37
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
HOOD, David A $105,687 4 Yr(s) BCA
York University (Toronto, Ontario)
Mitochondria in aging skeletal muscle
HOODLESS, Pamela A $146,839 3 Yr(s) DEV
University of British Columbia
B.C. Cancer Research Centre (Vancouver)
Formation and Patterning of the Definitive Endoderm
HUFF, Murray W $135,198 4 Yr(s) M
University of Western Ontario
Robarts Research Institute - U.W.O. (London, Ont.)
Regulation of Foam Cell Formation: Relationship to Atherosclerosis
HUGHES, Timothy R $218,492 5 Yr(s) GMX
University of Toronto
Comprehensive analysis of mouse and human transcription factor DNA-binding specificities
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
38
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
ISENRING, Paul $137,063 5 Yr(s) CSA
Université Laval
Hôtel-Dieu de Québec
Molecular mechanisms underlying the normal operation and the physiological role of the renal Na-K-Cl cotransporter splice variants.
ITIER, Roxane J ALAIN, Claude / MCINTOSH, Anthony R
 $67,108 3 Yr(s) BSC
Baycrest Centre for Geriatric Care (Toronto)
Modulations of the face and eye gaze processing brain networks
JABADO, Nada $126,779 3 Yr(s) CPT
The Research Institute of the McGill University Health Centre
Montreal Children's Hospital Research Institute
Identification and characterization of genes involved in the genesis and progression of pediatric astrocytomas.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
39
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
JEAN-CLAUDE, Bertrand J $98,685 3 Yr(s) CPT
McGill University
Royal Victoria Hospital (Montreal)
Single molecules engineered for the tandem delivery of Xeloda ® and EGFR/Her2 tyrosine kinase inhibitors: a novel multitargeted approach for the therapy of advanced breast cancers
JIA, Zongchao $160,565 5 Yr(s) BMA
Queen's University (Kingston, Ontario)
EF-hand proteins and calcium-mediated modulation
JIN, Tianru $112,724 5 Yr(s) M
University Health Network (Toronto)
Mechanisms underlying the production and homeostasis of the incretin hormone GLP-1
JOHNSON, Jeffrey A VEUGELERS, Paul J / YASUI, Yutaka
 $68,755 2 Yr(s) HSI
MARRA, Carlo A
University of Alberta
Cancer incidence for patients with Type 2 Diabetes exposed to oral hypoglycemics: Are there differences between agents?
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
40
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
JOLICOEUR, Paul $126,721 5 Yr(s) MCC
Institut de recherches cliniques de Montréal
Oncogenes and the interaction of retroviruses with the host
JULIEN, Jean-Pierre $133,300 5 Yr(s) NSB
Université Laval
Centre hospitalier de l'Université Laval (Québec)
The role of inflammation in pathogenesis and immunotherapy of ALS
JUNOP, Murray S $130,841 5 Yr(s) BMA
McMaster University
Unraveling the Molecular Mechanisms of Non- homologous DNA End-joining
KAARTINEN, Mari T $112,359 3 Yr(s) CIB
McGill University
Matrix crosslinking by Factor XIIIA and transglutaminase 2 during bone formation
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
41
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
KAPLAN, Gilaad G HILSDEN, Robert J / NGUYEN, Geoffrey C / WHEELER, Amanda J
 $96,696 2 Yr(s) PUB
VILLENEUVE, Paul J
University of Calgary
The effect of outdoor air pollution on the incidence and prognosis of the inflammatory bowel diseases in Canada
KARSAN, Aly $159,805 5 Yr(s) EM
University of British Columbia
B.C. Cancer Research Centre (Vancouver)
Innate immune signaling in hematopoiesis
KARSAN, Aly $141,043 5 Yr(s) CSA
University of British Columbia
B.C. Cancer Research Centre (Vancouver)
Endothelial to mesenchymal transformation
KASSOUF, Wassim LAPOINTE, Jacques / MANSURE, Jose J
 $128,945 3 Yr(s) CPT
The Research Institute of the McGill University Health Centre
Interrogating the mTOR Signaling Pathway in Bladder Cancer
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
42
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
KAUL, Padmaja R ARMSTRONG, Paul W / GRAHAM, Michelle M / NORRIS, Colleen / WELSH, Robert C
 $131,706 3 Yr(s) GSH
University of Alberta
Tracking gender differences in acute coronary syndromes: At the first point of care and beyond
KAUL, Rupert GELMON, Lawrence J / KIMANI, Joshua
 $121,896 3 Yr(s) VVP
University of Toronto
Antiretroviral rollout in a "core transmission" group of female sex workers: impact on mucosal co-infections and predictors of HIV transmission.
KEITH, Mary E LEONG-POI, Howard M / STEWART, Duncan J
 $118,783 3 Yr(s) NUT
St. Michael's Hospital (Toronto)
Defining the effects of B vitamins on the endogenous angiogenic response to ischemia
KHALIL, Abdelouahed
CUNNANE, Stephen / GRENIER, Guillaume
 $105,131 4 Yr(s) BCA
Université de Sherbrooke
Centre de recherche sur le vieillissement (QC)
Mécanismes d'action des paraoxonases 1 et 3 dans la régulation des propriétés anti- athérogènes des HDL au cours du vieillissement
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
43
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
KIM, Richard B DRESSER, George K / TIRONA, Rommel G
 $159,771 5 Yr(s) PS
University of Western Ontario
Hepatic Organic Anion Transporting Polypeptide (OATP) drug uptake transporters as determinants of drug disposition
KIROUAC, Gilbert J $104,691 5 Yr(s) BSA
University of Manitoba
Thalamic regulation of the nucleus accumbens
KIRSHENBAUM, Lorrie A $145,266 5 Yr(s) CSA
University of Manitoba
Molecular Determinants of Apoptosis in Heart
KISS, Robert S YAO, Zemin $105,629 3 Yr(s) M
The Research Institute of the McGill University Health Centre
Understanding of regulated intracellular cholesterol movement and cell growth through interplay between LRP1 and its adapter proteins
KOMAROVA, Svetlana V $115,842 5 Yr(s) CIB
McGill University
Regulation of osteoclast formation and function by cell-cell interactions in the bone microenvironment
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
44
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
KOZLOWSKI, Piotr MACKAY, Alexander L / TETZLAFF, Wolfram G
 $147,458 3 Yr(s) MPI
University of British Columbia
Development of MRI techniques for animal models of Spinal Cord Injury
LABRIE, Claude $138,651 5 Yr(s) E
Université Laval
Centre hospitalier de l'Université Laval (Québec)
Molecular mechanism of action of the membrane-bound transcription factor AIbZIP
LACAILLE, Diane V ABRAHAMOWICZ, Michal M / ANIS, Aslam H / ESDAILE, John M / TUGWELL, Peter S
 $115,543 2 Yr(s) HSI
The Arthritis Research Centre of Canada
Assessing the quality of care for rheumatoid arthritis at a population level
LAMARRE, Alain $128,290 3 Yr(s) VVP
INRS - (Québec, QC)
INRS-Institut Armand-Frappier (Laval)
Role of natural antibodies in promoting acquired immune responses to hepatitis C virus.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
45
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
LAMBE, Evelyn K $143,605 5 Yr(s) NSA
University of Toronto
Cellular and molecular mechanisms underlying development and plasticity of prefrontal attention circuitry
LANGLOIS, Marc-Andre $121,805 5 Yr(s) VVP
Université Laval
Centre hospitalier de l'Université Laval (Québec)
Molecular and cellular mechanisms involved in APOBEC3G-mediated innate immunity to HIV infection
LAPOINTE, Réjean PICCIRILLO, Ciriaco A $138,780 3 Yr(s) CBT
Centre Hosp. de l'Université de Montréal (CHUM)
Defining immunological checkpoints to enhance cancer immunotherapy
LAVOIE, Kim ARSENAULT, André / BACON, Simon L / DUPUIS, Jocelyn / PILOTE, Louise / VADEBONCOEUR, Alain
 $85,235 4 Yr(s)
6 Mths
 POP
Montreal Heart Institute
Improving prediction of cardiovascular morbidity and mortality in men and women using a new nuclear imaging technique designed to assess endothelial function by vascular reactivity
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
46
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
LE, Xiaochun C WEINFELD, Michael $128,871 3 Yr(s) CBT
University of Alberta
Mechanisms of arsenic carcinogenesis
LECLERC, Denis LAMARRE, Alain / LAPOINTE, Réjean
 $118,736 5 Yr(s) VVP
Université Laval
Centre hospitalier de l'Université Laval (Québec)
Characterization and improvement of the intrinsic adjuvant properties of papaya mosaic virus-like particles: An innovative vaccine platform.
LEE, Stephen
$158,919 5 Yr(s) MCC
University of Ottawa
Understanding the HIF2a Oncogenic Pathway in Human Cancer
LEE, Stephen COTE, Jocelyn $149,124 5 Yr(s) CBM
University of Ottawa
Anaerobic Nucleolar Proteome Dynamics
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
47
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
LEGARE, France ELWYN, Glyn / FROSCH, Dominick L / GRIMSHAW, Jeremy M / LABRECQUE, Michel / OUIMET, Mathieu / ROUSSEAU, Michel / STACEY, Dawn / STEWART, Moira A / VAN DER WEIJDEN, Trudy
 $108,922 2 Yr(s)
6 Mths
 KTE
Université Laval
EXACKTE 2: Exploiting the clinical consultation as a knowledge transfer and exchange environment
LEHOUX, Pascale N DENIS, Jean-Louis / MILLER, Fiona A / URBACH, David R / WILLIAMS-JONES, Bryn
 $88,143 1 Yr(s)
6 Mths
 KTE
Université de Montréal
Judgments and health innovation: How do upstream knowledge transfer and exchange among stakeholders contribute to the design of innovations
LEONG-POI, Howard M DICK, Alexander J / STEWART, Duncan J
 $132,926 3 Yr(s) MPI
St. Michael's Hospital (Toronto)
Molecular Imaging of Stem Cell Therapy Using Targeted Contrast Ultrasound
LEPAGE, Martin ESCHER, Emanuel / GUÉRIN, Brigitte / NEUGEBAUER, Witold A / PAQUETTE, Benoît
 $133,333 3 Yr(s) MPI
Université de Sherbrooke
Optimization and characterization of novel contrast agents for magnetic resonance imaging allowing the non-invasive detection of matrix metalloproteinases activity in vivo
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
48
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
LETOURNEAU, Nicole L BENZIES, Karen M / DENNIS, Cindy-Lee E / DOUCET, Andrea M / DUFFETT-LEGER, Linda A / MCGRATH, Patrick J / STEWART, Miriam J
 $86,835 2 Yr(s) GSH
University of New Brunswick (Fredericton)
Support for Fathers Affected by Postpartum Depression
LEVESQUE, Eric $125,387 3 Yr(s) IT
Université Laval
Hematopoietic stem cell (HCT) transplantation: Identification of key determinants of graft- versus-host disease.
LEVY, Emile DELVIN, Edgard E $140,325 5 Yr(s) EM
Hôpital Sainte-Justine (Montréal)
Gaining insight into cholesterol homeostasis in the small intestine: a special role for PCSK9
LIN, Sheng-Xiang POIRIER, Donald $125,715 5 Yr(s) E
Université Laval
Centre hospitalier de l'Université Laval (Québec)
Estrogenic 17beta-hydroxysteroid dehydrogenases contributing to breast cancer stimulation: 3D-structure, function and inhibition
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
49
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
LIPSHITZ, Howard D $165,858 5 Yr(s) DEV
University of Toronto
Post-transcriptional gene regulation during Drosophila development
LIU, Fei-Fei HUI, Angela B / O'SULLIVAN, Brian / PEREZ-ORDONEZ, Bayardo / PINTILIE, Melania
 $150,500 5 Yr(s) CPT
University Health Network (Toronto)
The Role of Micro-RNA's in Human Nasopharyngeal Carcinoma
LIU, Johne X $147,559 5 Yr(s) MCC
Ottawa Health Research Institute
Cdc42 Regulates Asymmetric Cytokinesis in Polar Body Extrusion
LIU, Mingyao $142,782 5 Yr(s) RS
University Health Network (Toronto)
Signal crosstalk in lung injury and repair
LOHNES, David L $196,495 5 Yr(s) DEV
University of Ottawa
Novel roles for Cdx proteins in development
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
50
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
LOMBER, Stephen G $171,162 5 Yr(s) BSC
University of Western Ontario
Adaptive Cortical Plasticity Following Deafness
LOPASCHUK, Gary D $124,577 5 Yr(s) CSB
University of Alberta
Energy substrate metabolism in the ischemic and non-ischemic heart
LORINCZ, Matthew C $148,481 5 Yr(s) G
University of British Columbia
Analysis of the Interplay Between Histone MTases, DNA Methylation and Proviral Silencing
LOUCKS, Eric B ABRAHAMOWICZ, Michal M / ENGERT, James C / HARPER, Samuel / LYNCH, John W / MEANEY, Michael J / PILOTE, Louise
 $62,622 3 Yr(s) PUB
Douglas Hospital Research Centre (Verdun, Québec)
Life Course Socioeconomic Position, Type II Diabetes, and Obesity: Potential Interactions with Genetic Polymorphisms
LUKOWIAK, Kenneth D $96,492 5 Yr(s) BSA
University of Calgary
How stress alters memory formation, reconsolidation and forgetting
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
51
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
LYND, Larry D MAIL, Walter J / MARRA, Carlo A / TAYLOR, Jeff G / TSUYUKI, Ross T
 $53,431 2 Yr(s) HPM
University of British Columbia
Study of Understanding Patients' Preferences on Remuneration and Transition Towards Pharmacists' Provision of Chronic Disease Management (SUPPORT 2)
LYND, Larry D FITZGERALD, J M / LAM, Stephen / MARRA, Carlo A / SIN, Donald
 $57,628 2 Yr(s) HSR
University of British Columbia
Evaluating the Association Between Inhaled Corticosteroid and Statin Use and the Development of Lung Cancer in COPD Patients: A Linked Health Database Study
LYTTON, Jonathan $175,986 5 Yr(s) CP
University of Calgary
Hippocampal Plasticity: Cellular & Molecular Physiology of the K-Dependent Na/Ca- Exchanger, NCKX2
MA, David W $108,619 3 Yr(s) NUT
University of Guelph
Role of caveolae and fatty acids in pubertal mammary gland development and carcinogenesis
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
52
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
MA, Weiya $94,510 3 Yr(s) PT
Douglas Hospital Research Centre (Verdun, Québec)
McGill University
Peripherally derived inflammatory mediators and chronic pain
MACAULAY, Calum E LANE, Pierre / POH, Catherine / ROSIN, Miriam P
 $87,394 3 Yr(s) BME
University of British Columbia
B.C. Cancer Research Centre (Vancouver)
Development and evaluation of in vivo confocal imaging of the oral mucosa: Applications in oral cancer screening, diagnosis and surveillance
MACDONALD, Scott A CALLAGHAN, Russell C / GUIMARAES BORGES, Guilherme L / ROTH, Eric / SALMON, Amy L / STOCKWELL, Tim R / WELLS, Samantha L
 $49,562 4 Yr(s) PSB
University of Victoria (British Columbia)
Patterns and consequences of cocaine and alcohol use for substance abuse treatment clients
MAI, Sabine
$98,978 3 Yr(s) MCC
University of Manitoba
The role of chromosome 11 in v-abl/myc- induced mouse plasmacytomagenesis
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
53
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
MARTIN, Alberto GOMMERMAN, Jennifer L $124,050 4 Yr(s) IT
University of Toronto
The Molecular Basis for Germinal Center Selection
MASSEY, Thomas E $163,452 5 Yr(s) PS
Queen's University (Kingston, Ontario)
Biotransformation and Molecular Toxicity of Pulmonary Carcinogens
MAYOR, Thibault $101,424 5 Yr(s) CBM
University of British Columbia
Proteomic Analysis of the Ubiquitin Proteasome System and the Protein Quality Control Machinery
MAYSINGER, Dusica $99,674 3 Yr(s) PS
McGill University
NANOMEDICINES: A Non-Invasive Approach to Neural Sensing, Imaging, and Chaperoning in the Compromised Nervous System
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
54
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
MCCUSKER, Christine T $94,597 3 Yr(s) RS
The Research Institute of the McGill University Health Centre
Meakins Christie Labs (Québec)
Mechanisms of tolerance induction through neonatal exposure to environmental antigens. Prevention of asthma and allergic rhinitis
MCDONALD, Patrick P $120,990 5 Yr(s) CIB
Université de Sherbrooke
Nuclear signaling in human neutrophils
MCELHANEY, Janet E KOLLMANN, Tobias R / MENEILLY, Graydon S
 $128,802 3 Yr(s) BCA
University of British Columbia
Vancouver Coastal Health Research Institute
Inflammaging, Diabetes & Metabolic Sydrome: Effect on T-Cell Responses to Influenza
MCGRATH, Jennifer J BROUILLETTE, Robert / CHAPUT, Jean-Philippe / CONSTANTIN, Evelyn / JARRIN, Denise C / KLINE, Rex B / LAMBERT, Marie / PARADIS, Gilles / POIRIER, Paul / TREMBLAY, Angelo
 $270,745 5 Yr(s) CHI
Concordia University (Montreal, Quebec)
Sleep and Obesity in Children and Adolescents: Identifying Pathogenic Pathways
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
55
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
MCINTYRE, Lynn CURTIS, Lori J / EMERY, John H / KIRKPATRICK, Sharon / MCLAREN, Lindsay / TARASUK, Valerie S / WOLFSON, Michael C
 $124,290 3 Yr(s) POP
University of Calgary
Policy Drivers of Food Insecurity in Canada, 1994-2006
MCNEILL, John H $131,174 3 Yr(s) CSB
University of British Columbia
Malonyl CoA-Independent Regulation of Carnitine Palmitoyltransferase-1 by ß adrenoceptor Signalling in the Heart
MENEGHINI, Marc D $150,524 5 Yr(s) BMB
University of Toronto
Functional analysis of a developmentally regulated Jumonji-family histone demethylation pathway in Saccharomyces cerevisiae.
MES-MASSON, Anne-Marie PROVENCHER, Diane M / TONIN, Patricia N
 $150,500 5 Yr(s) CPT
Centre Hosp. de l'Université de Montréal (CHUM)
Selection and validation of target genes implicated in the clinical and biological features of ovarian cancer
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
56
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
MEYER, Jeffrey H GEORGE, Tony P / HOULE, Sylvain / SELBY, Peter L / WILSON, Alan A
 $143,803 3 Yr(s) BSB
Centre for Addiction and Mental Health (Toronto)
Cigarette smoking and prefrontal monoamine oxidase-A (MAO-A) binding in health and depression
MILLER, Gregory E KOBOR, Michael S / MA, Roy / WROSCH, Carsten
 $189,406 5 Yr(s) PSB
University of British Columbia
The Psychobiology of Caregiving for a Spouse with Cancer
MILNER, Theodore E $70,372 2 Yr(s) MOV
McGill University
Efficacy of robot-assisted rehabilitation of hand function after stroke
MINTZES, Barbara J BARER, Morris L / BASSETT, Kenneth L / BEAULIEU, Marie- Dominique / CASSELS, Alan K / DURRIEU, Geneviève / MORGAN, Steven G / TEJANI, Aaron M / WILKES, Michael / WRIGHT, James M
 $141,119 2 Yr(s) HPM
LEXCHIN, Joel
University of British Columbia
Pharmaceutical sales representatives and patient safety: comparative cross-sectional survey
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
57
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
MISHARA, Brian L ALDERSON, Marie / CHAGNON, Francois / DAIGLE, Marc S / GREENFIELD, Brian J / HENRY, Melissa / LESAGE, Alain D / RAYMOND, Sylvaine / SOARES, Angelo / ST- LAURENT, Danielle / TOUSIGNANT, Michel
 $98,788 3 Yr(s) PSB
Université du Québec à Montréal
Suicide, santé mentale et milieu de travail: Étude des conséquences du suicide d'un travailleur sur la santé mentale des collègues et sur le climat de travail
MITCHINSON, Wendy L $55,368 3 Yr(s) ELH
University of Waterloo (Ontario)
History of Obesity in Canada, 1920-1980
MOORE, David M COUTINHO, Alex G / HOGG, Robert S / KING, Rachel L / MILLS, Edward J / NABIRYO, Christine
 $139,142 3 Yr(s) POP
MONTANER, Julio S
University of British Columbia
Antiretroviral therapy as an additional HIV prevention tool for sero-discordant couples in Uganda
MOQBEL, Redwan LACY, Paige $154,500 5 Yr(s) RS
University of Alberta
Intracellular Mechanisms in Eosinophil Exocytosis: Contribution to the Development of Airway Inflammation.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
58
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
MOREAU, Robert BRISSETTE, Louise $93,479 4 Yr(s) CIB
Université du Québec à Montréal
Functions of the scavenger receptors of class B in bone metabolism.
MOURAD, Walid M $101,145 5 Yr(s) IT
Centre Hosp. de l'Université de Montréal (CHUM)
The impacts of disulfide bond CD40/CD40 dimers in the biological responses.
MOURAD, Walid M HASSAN, Ghada / MERHI, Yahye
 $129,817 5 Yr(s) CSC
Centre Hosp. de l'Université de Montréal (CHUM)
Role of CD40 ligand in athero-thrombosis.
MÜLLER, Daniel J COHN, Tony A / KENNEDY, James L / REMINGTON, Gary / TIWARI, Arun K
 $161,486 5 Yr(s) BSB
Centre for Addiction and Mental Health (Toronto)
Genetics of Antipsychotic-Induced Metabolic Syndrome
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
59
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
MULLER, William J $128,630 5 Yr(s) MCC
McGill University
The role of phosphatidylinositol-3 kinase (PI3K) coupled signaling pathways in mammary tumorigenesis
MURPHY, Bruce D $147,932 5 Yr(s) E
Université de Montréal
Ovarian cell differentiation
NALBANTOGLU, Joséphine $105,136 4 Yr(s) MOV
KARPATI, George
McGill University
Molecular therapies for dystrophin deficiency
NANCI, Antonio $110,882 5 Yr(s) DS
MOFFATT, Pierre
SMITH, Charles E
Université de Montréal
Functional studies and experimental manipulation of ameloblastin expression
NANO, Francis E BORASTON, Alisdair B / GUTTMAN, Julian A
 $158,771 4 Yr(s) MI
University of Victoria (British Columbia)
Type six secretion system of the Francisella Pathogenicity Island
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
60
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
NANTHAKUMAR, Kumaraswamy $136,187 5 Yr(s) CSB
University Health Network (Toronto)
Mechanisms and Modulation of Spatio- temporal Organization of Human Ventricular Fibrillation
NATHENS, Avery B MORRISON, Laurie J / RUBENFELD, Gordon
 $119,787 1 Yr(s) HSI
St. Michael's Hospital (Toronto)
Trauma system design: an evaluation of structure and process
NG, Kenneth K $111,416 4 Yr(s) BMA
University of Calgary
Molecular structural basis of replication in medically important caliciviruses and flaviviruses
NGAN, Elton T
WOODWARD, Todd S $54,942 4 Yr(s) BSB
University of British Columbia
University Hospital (U.B.C.)
Physiological and behavioral evidence of conflict modulation failure in dual stream information processing in delusional schizophrenic patients.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
61
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
NICOLSON, Robert J DROST, Dick J / GELMAN, Neil / NEUFELD, Richard W / THEBERGE, Jean / WILLIAMSON, Peter C
 $127,989 3 Yr(s) BSB
London Health Sciences Centre Res. Inc. (Ont.)
Neurobiological Markers of Aberrant Connectivity in Autism
NITZ, Mark $86,873 3 Yr(s) MI
University of Toronto
De-N-acetylases in bacterial biofilm formation: The specificity, mechanism, and inhibition of IcaB and PgaB
NODWELL, Justin R $144,910 5 Yr(s) BMB
McMaster University
Links between antibiotic production and resistance in producer organisms
NOSKOV, Sergei DUFF, Henry J $90,743 3 Yr(s) CSA
University of Calgary
Mechanism of the high-affinity ligand binding and selective ion permeation in voltage-gated K-channels
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
62
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
OBERLANDER, Timothy F BOYCE, Thomas W / BRANT, Rollin F / DEVLIN, Angela M / DIAMOND, Adele / GRUNAU, Ruth E / MISRI, Shaila / WEINBERG, Joanne / YOUNG, Allan H
 $122,094 5 Yr(s) CHI
University of British Columbia
Executive Functions and stress reactivity in 5-7 year olds following prenatal serotonin reuptake inhibitor exposure
OHH, Michael $110,596 5 Yr(s) CBM
University of Toronto
Role of HIF in Endocytosis
OKEY, Allan B BOUTROS, Paul C $131,064 3 Yr(s) PT
University of Toronto
Dioxin toxicity: gene expression in a resistant rat model
OSBORNE, Lucy R $130,190 5 Yr(s) G
University of Toronto
Genetic analysis of Williams-Beuren syndrome: linking genes with cognition and behaviour
OVERALL, Christopher M $196,783 5 Yr(s) DS
University of British Columbia
Leukocyte Matrix Metalloproteinases (MMPs) in Arthritis
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
63
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
PAETZEL, Mark W $156,468 5 Yr(s) BMA
Simon Fraser University (Burnaby, B.C.)
Structural analysis of the molecular machinery involved in protein secretion and membrane protein assembly.
PAI, Madhukar DALEY, Peter / DENDUKURI, Nandini / DHEDA, Keertan / GREENAWAY, Christina A / MENZIES, Richard
 $100,626 3 Yr(s) PUB
The Research Institute of the McGill University Health Centre
Innovative approaches for diagnosing tuberculosis in the era of HIV
PANG, Elizabeth W CHEYNE, Douglas O / DE NIL, Luc F / ROBERTS, Sheila (Wendy) G
 $155,242 5 Yr(s) CHI
Hospital for Sick Children (Toronto)
Dissociating cognitive and motor components of healthy and dysfunctional expressive language development in children
PANG, Kim-Ching S $120,717 5 Yr(s) PS
University of Toronto
Interplay of Transporters, Enzymes, and Nuclear Receptors in First-Pass Drug Absorption
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
64
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
PAQUETTE, Benoît BUJOLD, Rachel / LEPAGE, Martin
 $88,626 3 Yr(s) CPT
Université de Sherbrooke
Improving radiotherapy of breast cancer with the COX-2 inhibitor NS-398
PARENT, Jean-Luc $141,943 5 Yr(s) CP
Université de Sherbrooke
Regulation of G protein-coupled receptor trafficking
PARISSENTI, Amadeo M CHAPMAN, Judith-Anne W / CONLON, Michael / KAHN, Harriette / MACLEAN, Dave A / TRUDEAU, Maureen E
 $111,280 3 Yr(s) CPT
Sudbury Regional Hospital (ON)
Aldoketoreductases and Their Role in Tumour Progression and Anthracycline Resistance in Human Breast Cancer
PARKINSON, Fiona E ANDERSON, Christopher M
 $119,841 5 Yr(s) PT
ALBENSI, Benedict C
University of Manitoba
Regulation of brain adenosine levels by ecto- enzymes and membrane transporters.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
65
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
PASTINEN, Tomi HARVEY, Edward J / RICHARDS, Brent
 $129,000 3 Yr(s) G
McGill University
Genomewide analysis of functional polymorphisms affecting human bone phenotypes
PATERSON, Barbara L LEBLANC, Denis / LOPPIE READING, Charlotte J / MOORE, Carla S / WIEN, Frederic C
 $102,347 2 Yr(s) ABH
University of New Brunswick (Fredericton)
"Talking with their feet": Origins and impact of and potential solutions to non-attendance in diabetes clinics by Aboriginal people
PATTEN, Scott B ELIASZIW, Michael / MARRA, Carlo A
 $70,003 3 Yr(s) PSB
University of Calgary
Major Depression and Health Status Changes
PAUDEL, Hemant K $134,809 3 Yr(s) BCA
Jewish General Hospital (Montreal)
Tau protein and Alzheimer's disease
PEI, York P PATERSON, Andrew D $132,526 3 Yr(s) G
University of Toronto
Molecular Genetics of IgA Nephropathy
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
66
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
PENG, Chun SHAW, Patricia A $133,300 3 Yr(s) E
York University (Toronto, Ontario)
The integrative role of Nodal, cyclin G2 and miR-376c in ovarian tumorigenesis
PETERS, Terence M LEE, Donald H / MIRSATTARI, Seyed M / PARRENT, Andrew G
 $141,416 5 Yr(s) MPI
University of Western Ontario
Image-guided surgery for epilepsy
PETRONIS, Arturas $293,530 3 Yr(s) BSB
Centre for Addiction and Mental Health (Toronto)
Epigenomics of Schizophrenia
PITTMAN, Quentin J $126,497 5 Yr(s) NSA
University of Calgary
Plasticity of neuroendocrine and autonomic synapses
POLYCHRONAKOS, Constantin $143,250 3 Yr(s) G
The Research Institute of the McGill University Health Centre
Novel genetic susceptibility loci for type 1 diabetes
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
67
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
POMEY, Marie-Pascale A CARPENTIER, Normand C / FOREST, Pierre-Gerlier / HUDON, Raymond / LAVIS, John N
 $76,486 3 Yr(s) HPM
Université de Montréal
Anatomy of Quebec's Decision-Making Process: The Chaoulli Decision
POSTOVIT, Lynne-Marie $127,001 5 Yr(s) MCC
University of Western Ontario
Role of Oxygen as a Regulator of Tumour Cell Plasticity and Metastatic Potential
POWELL, William S $143,165 5 Yr(s) PT
McGill University
Biosynthesis and role of eicosanoids in inflammation
PRADO, Vania F PRADO, Marco A $164,525 5 Yr(s) BCA
University of Western Ontario
The role of basal forebrain cholinergic neurons in synaptic plasticity and cognition.
PRAT, Alexandre ARBOUR, Nathalie $110,940 5 Yr(s) NSB
Centre Hosp. de l'Université de Montréal (CHUM)
Novel Adhesion Molecules of the Blood-Brain Barrier Regulating CNS Inflammation
* "Research Institution" is displayed only when it is different from "Institution Paid".
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68
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
PROCHAZKA, Arthur $113,901 5 Yr(s) BME
University of Alberta
Restoration of upper extremity function with a novel implanted neuroprosthesis.
PUNTHAKEE, Zubin HILL, Stephen A / MCQUEEN, Matthew J
 $71,118 3 Yr(s) POP
DEVEREAUX, Philip J
GERSTEIN, Hertzel C
McMaster University
Glucose as a predictor of Vascular events In noncardiac Surgery patIents cOhort evaluatioN (GlucoVISION)
RAJAH, Maria N GRADY, Cheryl L / PRUESSNER, Jens C
 $86,882 3 Yr(s) BCA
Douglas Hospital Research Centre (Verdun, Québec)
Dissociating regional changes in prefrontal cortex structure and function that impact memory performance during normal aging
REUDELHUBER, Timothy L $125,214 3 Yr(s) CSB
Institut de recherches cliniques de Montréal
Prorenin in health and disease
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
69
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
RICHARD, Denis $92,437 5 Yr(s) M
Université Laval
Institut universitaire de cardiologie et pneumologie de Québec
The Role of the Melanin-Concentrating Hormone System in the Regulation of Energy Balance
ROBAIRE, Bernard NAGANO, Makoto $148,322 5 Yr(s) E
McGill University
Aging of male germ cells
ROBERT, François COULOMBE, Benoît $137,699 1 Yr(s) GMX
Institut de recherches cliniques de Montréal
Systematic characterization of the proteome associated with specific genomic loci: A proof of concept
ROCHON, Paula A ANDERSON, Geoffrey M / BELL, Chaim M / BRONSKILL, Susan E / GRUNEIR, Andrea / SCHULL, Michael J
 $76,116 3 Yr(s) HSI
Baycrest Centre for Geriatric Care (Toronto)
Emergency Department Visits by Nursing Home Residents in Ontario: Descriptive Patterns of Resident Visits by Timing, Location, and Physician Availability
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
70
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
ROGER, Andrew J SIMPSON, Alastair G $143,876 5 Yr(s) GMX
Dalhousie University (Nova Scotia)
Major transitions in eukaryotic cell evolution.
ROKEACH, Luis A $112,338 3 Yr(s) CBM
Université de Montréal
The endoplasmic reticulum and programmed cell death
ROSEN, Kirill V LEE, Patrick W $112,459 3 Yr(s) MCC
Dalhousie University (Nova Scotia)
Anti-apoptotic mechanisms that mediate ras oncogene-driven tumor growth
ROSENBLUM, Norman D $155,828 5 Yr(s) EM
Hospital for Sick Children (Toronto)
Control of kidney cell determination and morphogenesis by BMPs and Beta-catenin
ROSKAMS, Angela J $151,033 5 Yr(s) CBM
University of British Columbia
Regulation of Brain Lipid Binding Protein in Growth-Promoting Glia
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
71
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
ROSKAMS, Angela J $148,178 5 Yr(s) NSB
University of British Columbia
A role for SPARC in the Regulation of CNS Repair
ROSKELLEY, Calvin D MCNAGNY, Kelly M $111,112 4 Yr(s) CPT
University of British Columbia
The role of the podocalyxin complex in tumor progression.
ROSSIGNOL, Serge $174,786 5 Yr(s) MOV
Université de Montréal
Adaptive mechanisms of spinal locomotion
ROUCOU, Xavier $141,210 5 Yr(s) CBM
Université de Sherbrooke
Molecular activity of prion protein oligomers in health and diseases
ROUILLARD, Claude MARTINOLI, Maria-Grazia $145,864 5 Yr(s) BSA
LEVESQUE, Daniel
Université Laval
Centre hospitalier de l'Université Laval (Québec)
Nuclear receptors and dopamine neurotransmission: A yin-yang relationship
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
72
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
ROULEAU, Guy A JULIEN, Jean-Pierre / PARKER, Jodey A / VANDE VELDE, Christine Diane C
 $169,522 5 Yr(s) NSA
Centre Hosp. de l'Université de Montréal (CHUM)
Cellular and biochemical impact of TDP-43 mutants in ALS
ROWE-MAGNUS, Dean A $106,550 4 Yr(s) MI
Sunnybrook Health Sciences Centre
Evolution of CPS and LPS diversity in V. vulnificus
ROZAKIS ADCOCK, Maria WHEELER, Michael B $79,765 3 Yr(s) M
University of Toronto
Role of PHIP in Beta Cell Function
ROZEN, Rima $137,067 5 Yr(s) NUT
The Research Institute of the McGill University Health Centre
Low dietary folate and colorectal carcinogenesis
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
73
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
RUEL, Marc DE KEMP, Robert A / GRIFFITH, May C / STEWART, Duncan J / WHITMAN, Stewart C
 $149,827 4 Yr(s) BME
SUURONEN, Erik
University of Ottawa
University of Ottawa Heart Institute
Mechanisms of Progenitor Cell-based Angiogenic Therapy with Tissue-Engineered Biopolymer Delivery Matrices and Effects of Host Substrate Modification
SABISTON, Catherine M O'LOUGHLIN, Jennifer L / WROSCH, Carsten
 $144,118 3 Yr(s) PSB
McGill University
Physical activity among breast cancer survivors: Understanding the impact on biological risk factors and psychological health over time.
SADAR, Marianne D ANDERSEN, Raymond J / WANG, Yuzhuo
 $151,203 3 Yr(s) E
University of British Columbia
B.C. Cancer Research Centre (Vancouver)
Discovery of new drug candidates for the clinical management of prostate cancer
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
74
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
SADIKOT, Abbas F $131,897 5 Yr(s) MOV
McGill University
Montreal Neurological Institute
Mechanisms by which Afferents Regulate Striatal Neuronal Loss and Motor Activity in Movement Disorders
SADOWSKI, Ivan J $118,374 3 Yr(s) VVP
University of British Columbia
Ras-responsive elements in HIV-1 replication and AIDS pathogenesis
SAREEN, Jitender ASMUNDSON, Gordon J / COX, Brian J / WANG, Jianli
 $60,000 2 Yr(s) PSB
University of Manitoba
Work Stress and Childhood Adversity in relation to Mental Disorders and Suicidality Among Canadian Soldiers: Analysis of a large Population-Based Sample
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
75
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
SATO, Sachiko TREMBLAY, Michel J $103,384 3 Yr(s) VVP
Université Laval
Centre hospitalier de l'Université Laval (Québec)
Biochemical, cellular and molecular studies to dissect the contribution of the soluble host carbohydrate binding proteins to HIV-1 pathogenesis
SAVARD, Pierre BUSCHMANN, Michael D / LAVIGNE, Patrick / LI, Leping
 $121,099 4 Yr(s) BME
École polytechnique de Montréal
Electroarthrography: an original approach for the non-invasive measurement of load-induced electric fields in the knee joint for diagnosis of joint function and joint disease
SCHILLER, Peter W $135,814 5 Yr(s) PS
Institut de recherches cliniques de Montréal
Neuropeptides and peptidomimetics as parmacological tools and potential drugs
SCHUURMANS, Carol J $135,115 5 Yr(s) DEV
University of Calgary
Molecular regulation of layer formation in the developing CNS
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
76
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
SEFTON, Michael V WOODHOUSE, Kimberly A $94,540 3 Yr(s) BME
University of Toronto
Modular Tissue Engineering
SERIES, Frédéric H SIMILOWSKI, Thomas $120,310 5 Yr(s) RS
Université Laval
Institut universitaire de cardiologie et pneumologie de Québec
Pathophysiology of sleep disordered breathing
SHAH, Girish M GRAZIANI, Grazia / PASIEKA, Janice L
 $156,347 4 Yr(s) CBT
Université Laval
Centre hospitalier de l'Université Laval (Québec)
Potentiation of chemotherapy of neuroendocrine carcinoid tumors by PARP-inhibitors
SHATENSTEIN, Bryna GAUVIN, Lise / KELLER, Heather H / PAYETTE, Hélène / RICHARD, Lucie
 $56,877 1 Yr(s) SDA
Institut universitaire de gériatrie de Montréal
The impact of personal characteristics and social factors on food choices and adaptive strategies for maintaining diet quality among community-dwelling older adults
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
77
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
SHERMAN, Philip M $150,500 5 Yr(s) MI
Hospital for Sick Children (Toronto)
Epithelial cell signalling responses to attaching- effacing intestinal pathogens
SHERWIN, Barbara B $70,089 4 Yr(s) BCA
McGill University
Estrogen and Cognitive Aging in Women: A Test of the Critical Period Hypothesis
SHOICHET, Molly S TATOR, Charles H $129,011 4 Yr(s) BME
University of Toronto
Minimally-invasive Drug Delivery Strategy for Acute Spinal Cord Injury Repair
SIDANI, Souraya CAIRNEY, John / MIRANDA, Joyal / STREINER, David L
 $48,663 2 Yr(s) HSR
Ryerson University (Toronto)
Influence of Treatment Attributes on Preferences for Behavioral and Pharmacological Treatments
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
78
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
SIDEN, Harold B BRANT, Rollin F / CADELL, Susan Anne / DAVIES, Elizabeth M / STRAATMAN, Lynn
 $260,935 5 Yr(s) CHI
STEELE, Rose G
University of British Columbia
Charting the Territory: Determining and Documenting Trajectories for Families Where a Child Has a Life-Threatening Condition
SIMS, Stephen M $162,545 5 Yr(s) CP
DIXON, S. Jeffrey
University of Western Ontario
Role of Cytosolic Calcium in the Regulation of Osteoclasts and Bone Resorption
SINAL, Christopher J $138,982 3 Yr(s) BCA
Dalhousie University (Nova Scotia)
Chemerin/CMKLR1: A Molecular Switch to Regulate Bone Marrow Adipogenesis and Osteoblastogenesis
SINGH, Shiva M $183,166 3 Yr(s) BSB
O'REILLY, Richard L
SCHERER, Stephen W
University of Western Ontario
Gene discovery in schizophrenia using copy number variations (CNVs) in high-risk monozygotic (MZ) and dizygotic (DZ) twins
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
79
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
SKAMENE, Emil FORTIN, Anny / GROS, Philippe / SLADEK, Robert G / VIDAL, Silvia M
 $199,262 5 Yr(s) G
The Research Institute of the McGill University Health Centre
Genetic Dissection of Host Response Against Respiratory Virus Infections in Recombinant Congenic Strains of Mice
SLEIMAN, Hanadi AUTEXIER, Chantal / MOITESSIER, Nicolas R
 $103,673 3 Yr(s) CBT
McGill University
Supramolecular Complexes as G-Quadruplex Binders: Towards Effective Telomerase Inhibition
SMITH, Dawn A ANDREW, Caroline P / EDWARDS, Nancy C / PETERSON, Wendy
 $65,682 2 Yr(s) ABH
University of Ottawa
Improving access to preventive early childhood services for urban Aboriginal families: A participatory research study
SNIDER, Laurie M BOS, Arend F / MAJNEMER, Annette / MAZER, Barbara L
 $41,011 2 Yr(s) CHI
McGill University
The predictive validity of the general movements assessment of infants born preterm for functional outcomes at six years of age
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
80
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
SOJA, Peter J $122,952 5 Yr(s) BSC
University of British Columbia
Sensory Inflow Through the Spinothalamic Tract During Normal vs. Restricted Sleep
SONG, Cai $91,333 3 Yr(s) BSA
University of Prince Edward Island (Charlottetown)
Interleukin-1beta, neurodegeneration, and memory impairment: an insight into imbalances between pro- and anti-inflammation, and between neurotoxicity and neuroprotection
SRAYKO, Martin A $133,672 4 Yr(s) CP
University of Alberta
Approaches to understand the regulation of microtubules and microtubule motor proteins in mitotic spindle assembly and the positioning of intracellular structures.
ST-PIERRE, Yves $97,633 3 Yr(s) CPT
INRS - (Québec, QC)
INRS-Institut Armand-Frappier (Laval)
The role of galectin-7 in mammary tumorigenesis and metastasis
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
81
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
STANFORD, William L $315,949 5 Yr(s) GMX
BADER, Gary D
MORRIS, Quaid D
ZANDSTRA, Peter W
University of Toronto
Transcription Networks Controlling Human Embryonic Stem Cell Fate
STELLWAGEN, David $147,738 5 Yr(s) NSB
The Research Institute of the McGill University Health Centre
The role of TNFalpha in synaptic plasticity and during neurodegeneration
STEVENS, Bonnie J ASZTALOS, Elizabeth V / BEYENE, Joseph / HOWLETT, Alexandra A / JOHNSTON, Celeste / MCNAMARA, Patrick J / O'BRIEN, Karel / PILLAI RIDDELL, Rebecca Rita E
 $184,734 4 Yr(s) PSB
GIBBINS, Sharyn A
MCGRATH, Patrick J
Hospital for Sick Children (Toronto)
Pain in Infants at risk for Neurological Impairment: A Program of Research: Phase 3
STIFANI, Stefano $154,750 5 Yr(s) NSA
McGill University
Basal Telencephalic Limbic System Development
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
82
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
STOLEE, Paul BERG, Katherine O / BYRNE, Kerry / CHESWORTH, Bert M / COOK, Richard J / EGAN, Mary Y / FORBES, Dorothy A / HIRDES, John P / JAGLAL, Susan B / POSS, Jeff W / WELLS, Jennie / ZHU, Mu
 $127,524 2 Yr(s) HSI
University of Waterloo (Ontario)
Enhancing home care rehabilitation through better use of health information
STRONG, Michael J $171,530 3 Yr(s) NSA
University of Western Ontario
Robarts Research Institute - U.W.O. (London, Ont.)
The role of TDP-43 in regulating NFL mRNA metabolism.
SULLIVAN, Robert $127,184 3 Yr(s) E
Université Laval
Sperm proteins acquired during epididymal transit: functions and usefulness for diagnostic of man infertility
SURETTE, Michael G $107,666 5 Yr(s) MI
University of Calgary
Polymicrobial Infections and Pathogenesis of the Streptococcus Milleri Group
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
83
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
SZATMARI, Peter BRYSON, Susan E / FERNANDEZ, Bridget A / GOLDBERG, Jeremy / MAHONEY, William J / PATERSON, Andrew D / ROBERTS, Sheila (Wendy) G / SCHERER, Stephen W / TUFF, Lawrence / VINCENT, John B / ZWAIGENBAUM, Lonnie
 $155,946 5 Yr(s) BSB
McMaster University
The Genetic Epidemiology of Autism; Family and Molecular Studies
TALJAARD, Monica BORUCH, Robert F / BREHAUT, Jamie C / BROWN, Judith B / DONNER, Allan / ECCLES, Martin P / SAGINUR, Raphael / ZWARENSTEIN, Merrick F
 $93,996 3 Yr(s) ELH
GRIMSHAW, Jeremy M
WEIJER, Charles E
Ottawa Health Research Institute
Ethical and policy issues in cluster randomized trials
TANENTZAPF, Guy $112,864 4 Yr(s) CP
University of British Columbia
Analysis of Integrin Function in Muscle Formation and Maintenance.
TANNENBAUM, Cara BELLEVILLE, Sylvie N / MULSANT, Benoit H
 $129,482 5 Yr(s) BCA
Institut universitaire de gériatrie de Montréal
Querying cognition and pharmacologic treatment of urinary incontinence in the elderly
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
84
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
TANNOCK, Ian F $127,822 3 Yr(s) CPT
University Health Network (Toronto)
Princess Margaret Hospital (Toronto)
Repopulation and chemotherapy
TEPASS, Ulrich $172,854 5 Yr(s) CP
University of Toronto
Regulation of epithelial polarity
THOMAS, David Y CARLILE, Graeme W / HANRAHAN, John W / ROBERT, Renaud S
 $114,036 5 Yr(s) RS
McGill University
Mechanisms of correction of deltaF508CFTR
THOMPSON, Alison $113,449 3 Yr(s) PS
Dalhousie University (Nova Scotia)
Design, Synthesis and Evaluation of Prodigiosin Analogues as Chemotherapeutic Agents
THOMPSON, Roger J $117,436 5 Yr(s) NSB
University of Calgary
Pannexin-1 Hemichannel Activation in Neurons.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
85
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
THORIN, Eric FERLAND, Guylaine / HAMEL, Edith
 $115,163 3 Yr(s) CSC
Montreal Heart Institute
Risk factors for cardiovascular diseases and cerebrovascular function
THORIN, Eric $149,289 5 Yr(s) PT
Montreal Heart Institute
Ageing of the vascular endothelium
TRASLER, Jacquetta M NAGANO, Makoto / ZINI, Armand S
 $161,694 5 Yr(s) GSH
The Research Institute of the McGill University Health Centre
Montreal Children's Hospital Research Institute
Sex-specific susceptibility for fetal origins of adult disease and transgenerational effects
TRIGGS-RAINE, Barbara L $151,222 5 Yr(s) G
University of Manitoba
Constitutive and regulated pathways of hyaluronan degradation
TRUONG, Kien K $66,437 3 Yr(s) BME
University of Toronto
Live cell imaging of caspase specific kinetics using fluorescent protein biosensors
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
86
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
TRUS, Micheal R SINGH, Gurmit $123,934 1 Yr(s) CPT
McMaster University
Juravinski Cancer Centre (Hamilton, ON)
Identification of Targets for Novel Acute Myeloblastic Leukemia Treatments
TSUI, Ban C $49,489 3 Yr(s) CIA
University of Alberta
Electrical impedance: a novel approach for detecting intraneural needle placement in regional anesthesia.
TYMIANSKI, Michael $179,793 5 Yr(s) NSB
University Health Network (Toronto)
Toronto Western Hospital
Role of TRPM Channels in Ischemic Brain Damage
UNDERHILL, T. Michael $139,953 5 Yr(s) DS
University of British Columbia
Delineating the Molecular Mechanisms Underlying BMP Action
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
87
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
UNGAR, Michael ANDREOU, Pantelis / CARREY, Normand / DONNON, Tyrone L / LEBLANC, John C / THIESSEN, Victor
 $136,462 5 Yr(s) CHI
Dalhousie University (Nova Scotia)
Adversity and Resilience among early teens: What predicts positive outcomes in later adolescence?
URBACH, David R BAXTER, Nancy N / LIX, Lisa M / SIMUNOVIC, Marko / SUTRADHAR, Rinku
 $209,445 5 Yr(s) HSR
University Health Network (Toronto)
Structures and Processes of Care in Colorectal Cancer Surgery (SPoCCS) Study
VACRATSIS, Panayiotis $81,614 3 Yr(s) MOV
University of Windsor (Ontario)
Molecular mechanisms regulating myotubularin-related lipid phosphatases mutated in neuromuscular diseases
VANCE, Dennis E
$167,668 5 Yr(s) M
University of Alberta
Phosphatidylcholine metabolism and obesity
VERREAULT, Alain $138,426 5 Yr(s) BMB
Université de Montréal
Chromatin Assembly during DNA Replication
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
88
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
VIAU, Victor $153,421 5 Yr(s) BSA
University of British Columbia
Androgen sensitive pathways to the paraventricular nucleus of the hypothalamus
VON DER WEID, Pierre-Yves $137,832 5 Yr(s) EM
University of Calgary
Mechanisms of Distension-Activated Contractility in Lymphatic Vessels: Importance for edema resolution
VON HARSDORF, Rudiger $151,886 5 Yr(s) CSA
University Health Network (Toronto)
Cardiac growth control by E2F4
WAGNER, James R CADET, Jean $107,402 3 Yr(s) CBT
Université de Sherbrooke
DNA repair and mutagenic potential of oxidized cytosine and 5-methylcytosine
WALLACE, John L $158,609 5 Yr(s) EM
University of Calgary
NSAID Gastropathy and Cytoprotection
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
89
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
WANG, Jianli CURRIE, Shawn R / PATTEN, Scott B / SAREEN, Jitender / SCHMITZ, Norbert
 $63,345 3 Yr(s) POP
University of Calgary
Perceived needs and utilization of workplace mental health accommodations among workers with depressive and anxiety disorders
WANG, Lu-Yang $157,229 5 Yr(s) NSA
Hospital for Sick Children (Toronto)
Spatial and temporal plasticity of neurotransmitter release at a developing central synapse
WANG, Rennian $131,229 3 Yr(s) M
University of Western Ontario
Determination of the Mechanisms by which the c-Kit Tyrosine Kinase Receptor Regulates Pancreatic Beta Cell Development, Function and Survival.
WANG, Yu Tian $204,293 5 Yr(s) NSB
University of British Columbia
Regulation of postsynaptic expression and function of GABA-A receptors
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
90
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
WARD, Michael E $129,900 3 Yr(s) CSB
BACKX, Peter H
St. Michael's Hospital (Toronto)
Oxygen Regulation of Membrane Potential by a GTP-gated Chloride Current in Proliferating Pulmonary Artery Smooth Muscle.
WARD, Wendy E $93,771 3 Yr(s) NUT
University of Toronto
Neonatal isoflavone exposure and long term programming of bone metabolism
WEEKS, Gerald $146,176 5 Yr(s) CP
University of British Columbia
The role of Rap1 in regulating cell function
WEINER, Joel H $114,626 5 Yr(s) BMA
University of Alberta
Bacterial complex II homologs as models for mitochondrial electron transfer
WEKSBERG, Rosanna ROBERTS, Sheila (Wendy) G / SCHERER, Stephen W
 $186,196 3 Yr(s) G
Hospital for Sick Children (Toronto)
Genome-Wide DNA Methylation Profiling in Autism
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
91
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
WELLINGTON, Cheryl L DONKIN, James / FAN, Jianjia
 $187,482 5 Yr(s) BCA
University of British Columbia
Child and Family Research Institute
The role of ABCA1 and apolipoprotein E in brain lipid metabolism and amyloidogenesis
WILKINSON, Mark D MCMANUS, Bruce M $133,178 4 Yr(s) GMX
University of British Columbia
St. Paul's Hospital, Vancouver
CardioSHARE: Design of an integrated query and analysis framework for ischemic heart disease data
WINSTANLEY, Catharine A $126,693 5 Yr(s) BSA
University of British Columbia
Determining the effects of monoaminergic regulation of frontostriatal systems in different aspects of impulsive decision-making.
WONG, Agnes GOLTZ, Herbert C / MIRABELLA, Giuseppe
 $95,673 5 Yr(s) CIA
Hospital for Sick Children (Toronto)
Timing of Surgery for Crossed Eyes in Infancy: A Clinical Evaluation of Sensory and Motor Outcomes
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
92
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
WONG-WYLIE, Douglas R $60,000 3 Yr(s) BSC
University of Alberta
Physiological, Anatomical and Molecular Organization of the Cerebellum
WOOD, Janet M $84,731 3 Yr(s) CP
University of Guelph
Characterization of osmolytes and osmolyte transporters that confer osmotic, thermal, oxidative and urea stress tolerance on Escherichia coli cells
WOODGATE, Roberta L BORTON, Barbara L / EDWARDS, Marie P / HALLMAN, Bonnie C / REMPEL, Gina R / RIPAT, Jacqueline D
 $79,768 3 Yr(s) CHI
University of Manitoba
Changing geographies of care: Using therapeutic landscapes as a framework to understand how families with medically complex children participate in communities
WOODWARD, Todd S HONER, William G / MORITZ, Steffen / NGAN, Elton T
 $99,608 4 Yr(s) BSB
University of British Columbia
Integration of Disconfirmatory Evidence in Schizophrenia: Cognitive and Neural Underpinnings
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
93
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
XIANG, Jim (Jianhua) $123,201 4 Yr(s) PS
University of Saskatchewan
CD4+ T-Cell vaccine capable of breaking immune tolerance, A novel anti-cancer pharmaceutical.
YAN, Andrew T DICK, Alexander J / GOLDSTEIN, Marc / LEONG-POI, Howard M / WU, Louis
 $101,376 3 Yr(s) CSB
WALD, Ron
St. Michael's Hospital (Toronto)
Impact of in-centre nocturnal hemodialysis on ventricular remodeling and function in end- stage renal disease
YU, Dickie C MARTIN, Garry L $73,509 3 Yr(s) BSB
University of Manitoba
Improving the quality of life for people with severe and profound intellectual disabilities: Studies of choice making
YUSUF, Salim GILMORE, Anna B / MCKEE, Martin / POGUE, Janice M / SANKARANARAYANAN, Subramanian V / TEO, Koon K
 $143,385 2 Yr(s) POP
CHOW, Clara K
McMaster University
Upstream Determinants of Smoking in Low, Middle and High Income Countries participating in PURE (Prospective Urban Rural Epidemiologic study)
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
94
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
ZACKSENHAUS, Eldad $149,253 5 Yr(s) CBM
University Health Network (Toronto)
Effect of pRb phosphorylation on development and disease
ZAPH, Colby $119,970 5 Yr(s) IT
University of British Columbia
Memory TH2 cell responses during helminth infection
ZATORRE, Robert J SCHONWIESNER, Marc $159,057 5 Yr(s) BSC
McGill University
Montreal Neurological Institute
Mapping the human auditory cortex: low-level features and higher-order interactions
ZENG, Haishan $78,013 4 Yr(s) MPI
LAM, Stephen
University of British Columbia
B.C. Cancer Research Centre (Vancouver)
Rapid Multi-spectral Imaging of Tissue Physiological and Morphological Changes for Endoscopic Lung Cancer Detection and Localization
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
95
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
ZHANG, Li $177,360 5 Yr(s) IT
University Health Network (Toronto)
Molecular Mechanisms of DN regulatory T cell- mediated donor specific transplantation tolerance.
ZOCHODNE, Douglas W $111,945 5 Yr(s) NSA
University of Calgary
Diabetes, neuron degeneration and insulin signaling
ZUNIGA-PFLUCKER, Juan C $137,013 5 Yr(s) IT
Sunnybrook Health Sciences Centre
Study of pre-T cell receptor signals regulating thymocyte differentiation.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
96
Peer Review Committees
PRC Name
ABH Aboriginal Peoples' Health
BCA Biological and Clinical Aspects of Aging
BMA Biochemistry & Molecular Biology - A
BMB Biochemistry & Molecular Biology - B
BME Biomedical Engineering
BSA Behavioural Sciences - A
BSB Behavioural Sciences - B
BSC Behavioural Sciences - C
CBM Cell Biology & Mechanisms of Disease
CBT Cancer Biology & Therapeutics
CHI Children's Health
CIA Clinical Investigation - A
CIB Clinical Investigation - B
CP Cell Physiology
CPT Cancer Progression & Therapeutics
CSA Cardiovascular System - A
CSB Cardiovascular System - B
CSC Cardiovascular System - C
DEV Developmental Biology
DS Dental Sciences
E Endocrinology
ELH Health Ethics, Law & Humanities
EM Experimental Medicine
G Genetics
GMX Genomics
GSH Gender, Sex & Health
HPM Health Policy & Systems Management Research
HSI Health Services Evaluation and Interventions Research - B
HSR Health Services Evaluation & Interventions Research - A
IT Immunology and Transplantation
KTE Knowledge Translation & Exchange
M Metabolism
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
97
MCC Molecular & Cellular Biology of Cancer
MI Microbiology & Infectious Diseases
MOV Movement & Exercise
MPI Medical Physics & Imaging
NSA Neurosciences - A
NSB Neurosciences - B
NUT Nutrition, Food & Health
PLC Palliative & End of Life Care
POP Public, Community & Population Health - A
PS Pharmaceutical Sciences
PSB Psychosocial, Sociocultural & Behavioural Determinants of Health - A
PT Pharmacology & Toxicology
PUB Public, Community and Population Health - B
RS Respiratory System
SDA Social Dimensions in Aging
VVP Virology & Viral Pathogenesis
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
98