Regenerative Medicine and Nanomedicine Initiative - Emerging Team Grants - July 2007

The Regenerative Medicine and Nanomedicine Initiative (RMNI) and its partners are pleased to announce the results of the Regenerative Medicine and Nanomedicine – Emerging Team Grants competition – July 2007.

This competition marked the fourth request for applications (RFA) in Regenerative Medicine and Nanomedicine (RMNI), one of the major initiatives of the Canadian Institutes of Health Research (CIHR). In collaboration with leading health research organizations, this announcement provided research support in the areas of Nanotechnology Applied to Health (Nanomedicine), Stem Cells, Tissue Engineering, and Rehabilitation Sciences.

Key to this initiative is a multi-disciplinary commitment to addressing the larger health issues and questions within this emerging field. The long-term goal is to develop innovative and socially validated treatment approaches based on the science of regenerative medicine and nanomedicine that will ultimately result in improved quality of life for individuals, their families, and populations.

Fifty two Letters of Intent (LOI) were received for the November 1, 2006 competition, of which thirty were invited to submit full applications. Twenty six full applications were received, and nine were approved for funding with a total commitment of $20,069,594 over 5 years.

The list provides the name of the principal grantee and co-applicant(s), title, average annual operating budget approved, term of the grant, and whether any condition has been placed on approval of the grant ("Pending"). The total number of applications received, the total number of applications funded and the total dollar investment include any grants that require Stem Cell Oversight Committee review; however, these applications will only be posted on the list of successful applications following further consideration by Governing Council. If an application falls into this category, then the Nominated Principal Investigator is notified in the Letter of Decision.

The applications approved for funding through the Regenerative Medicine and Nanomedicine Initiative are listed below.

Results of the Strategic Initiative	Applications Received	Applications Approved
Team Grants	26	9

 

Principal Investigators Institution Paid Title	Co-Applicant (s)	Average Annual Operating Amount	Term	Funding by	Pending
LANSDORP, Peter B.C. Cancer Research Centre (Vancouver) Chromatin marks in normal and malignant stem cells	Humphries, Richard;Hirst, Martin; Lefebvre, Louis; Lorincz, Matthew; Jones, Steven	$498,637	5 years	CIHR
MILLER, Freda Hospital for Sick Children (Toronto) Stem cells to treat spinal cord injury	Tetzlaff, Wolfram; Kaplan, David; Weiss, Samuel; Kwon, Brian;	$495,132	5 years	CIHR/Institute of Musculoskeletal Health and Arthritis (IMHA)/Institute of Neurosciences, Mental Health and Addiction (INMHA)
MOLDAY, Robert S. University of British Columbia Novel gene therapy approaches for the treatment of retinal degenerative diseases	Hu, Jim; Koenekoop, Robert; Sarunic, Marinko; Hauswirth, William;	$480,025	5 years	CIHR/Institute of Genetics (IG)/Institute of Neurosciences, Mental Health and Addiction (INMHA) /Foundation Fighting Blindness (FFB)
ROULEAU, Guy A. Centre Hospitalier de l'Université de Montréal (CHUM) Emerging Team in development of strategies for uptake and analysis of nanosequencing-derived data sets and linking to disease	Drapeau, Pierre; Bouvier, Michel; Chouinard, Sylvain; Dubé, Marie-Pierre; Michaud, Jacques; Samuels, Mark; Lespérance, Paul; Awadalla, Philip; Knoppers, Bartha	$450,000	5 years	CIHR / Institute of Neurosciences, Mental Health and Addiction (INMHA)
TIAN, Ganghong University of Manitoba Development of a multidisciplinary stem-cell program to fight congestive heart failure	Arora, Rakesh; Simard, Benoit; Tomanek, Boguslaw; Goertzen, Andrew; Deng, Jixian; Zhang, Shetuan; Jassal, Davinder; Freed, Darren; Xie, Jiuyong; Mzengeza, Shadreck	$251,806	5 years	CIHR/Institute of Genetics (IG)/ Institute of Circulatory and Respiratory Health (ICRH)
WEST, Lori J. University of Alberta Nanomedicine in organ transplantation: Polysaccharide structures as immunologic tolerogens for infant heart transplantation	Buriak, Jillian; Lowary, Todd; Cramb, David; Cairo, Christopher; Rajotte, Raymond; Gill, Ronald	$404,214	5 years	CIHR / Institute of Genetics (IG) /Institute of Circulatory and Respiratory Health (ICRH)/Institute of Infection and Immunity (III)