Randomized Controlled Trials - September 2007

Within the Randomized Controlled Trials program, the review committee has the discretion to assign an "Under Continuing Review (UCR)" rating to those applications where there is/are minor concern(s), or additional information/clarification is required to complete the review process. Following the peer review meeting, the relevant applicants are asked to respond to specific questions, which are subsequently reviewed and assessed by the committee on an ad-hoc basis. Due to this process, announcement of all the successful grants in this program is delayed. Results will be posted as soon as they become available.

* indicates a multicentre study

Principal Investigators
Institution/Title		 Co-investigators Term (years) 1st Year amount Total Amount approved

BHANDARI, Mohit
McMaster University

Fixation using alternative implants for the treatment of hip fractures (FAITH): A multi-centre randomized trial comparing sliding hip screws and cancellous screws on revision surgery rates and quality of life in the treatment of femoral neck fractures*

 Brink, O., Coles, C., Devereaux, P.J., Einhorn, T., Guyatt, G., Heetveld, M., Jeray, K., Karanicolas, P., Poolman, R., Richardson, M., Rosen, C., Schemitsch, E.H., Tornetta, P., Wai, E., Walter, S., Swiontkowski, M., Koval, K., Sanders, D., Sancheti, P., Frihagen, F., Tetworth, K., Klein, M. 2 $97,436 $160,267

EXNER, Derek, V.
University of Calgary

Investigating non-response to cardiac resynchronization: Evaluation of methods to eliminate non-response & target appropriate lead location (INCREMENTAL)*

 Phillipon, F., Yee, R. 4 $415,781 $1,645,373

HUTTON, Eileen K.
McMaster University

Early external cephalic version 2 trial*

 Willan, A.R., Hannah, M., Gafni, A., Ohlsson, A., Barrett, J., Ross, S.J., Windrim, R., Delisle, M-F., Carson, G.D., Dunn, M., Pollard, J.K., Natale, R. 2 $169,822 $213,763

LOEB, Mark B.
McMaster University

Does vaccinating healthy Hutterite children against influenza prevent influenza in other Hutterite colony members: A cluster randomized controlled trial*

 Walter, S., Earn, E., Babiuk, L., Russell, M., Aoki, F.Y., Fox, J., Horsman, G., Van Caeseele, P., Chokani, K., Vooght, M., Goeree, R.A. 3 $1,240,451 (includes $26,391 for equipment) $3,715,945

MAGEE, Laura A.
University of British Columbia

The CHIPS trial (control of hypertension in pregnancy study)*

 Von Dadelszen, P., Gafni, A., Gruslin, A.M., Helewa, M.E., Lee, S.K., Logan, A.G., Moutquin, J-M., Rey, E.E., Ross, S.J., Singer, J., Armson, B.A., Hutton, E.K., Asztalos, E.V., Murphy, K.E. 6 $441,640 $3,743,575

NIGAM, Anil
Montreal Heart Institute

Randomized trial of the effect of long-chain n-3 polyunsaturated fatty acids on arrhythmia recurrence in atrial fibrillation*

 Roy, D., Talajic, M., Lambert, J., Nattel, S., Tardif, J-C., Jones, P. 2 $751,900 (includes $66,500 for equipment) $1,027,688
The following Randomized Controlled Trial is funded by the CIHR/Rx & D Research Program, in collaboration with Novartis Inc.

KUMAR, Deepali
University of Alberta

Humar, Atul
University of Alberta

Pandemic influenza vaccine in organ transplantation (PIVOT trial): Safety and immunogenicity of pandemic influenza vaccine in kidney transplant recipients

 Roy, D., Talajic, M., Lambert, J., Nattel, S., Tardif, J-C., Jones, P. 3 $27,000 $65,000

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