Year 5 - International Review Panel Report, 2000-2005

Appendix 2 - International Review Panel Members

[ Table of Contents ]

John I. Bell
Chair - International Review Panel
Regius Professor of Medicine, Oxford University, Oxford, UK

A Canadian Rhodes Scholar, Professor Bell trained in medicine at Oxford and did postgraduate work in London and at Stanford University. At Stanford, his interest in immunology and genetics led to research on susceptibility to autoimmune diseases. Returning to Oxford as a Wellcome Trust Senior Clinical Fellow in 1987, Bell assumed the Nuffield Professorship of Clinical Medicine there in 1992 where he led the expansion in biomedical research. A member of Oxford University Council, he became the Regius Professor of Medicine in 2002. He is President Elect of the Academy of Medical Sciences.

Professor Bell has pioneered the development of research programs and clinical research in genetics and genomics across the UK. The founder of the Wellcome Trust Centre for Human Genetics, Bell's research has contributed to a clearer understanding of genetic determinants of susceptibility in Type 1 diabetes and rheumatoid arthritis and also the molecular origins of immune activation. He has helped develop genomic methodologies in the area of structural genomics, ENU mutagenesis and genetics.

Professor Bell sits on a wide range of biomedical research advisory panels in Canada, Sweden, Denmark, France, Singapore and the UK, including AstraZeneca (1997-2000) and Roche Palo Alto (since 1998) and has been a non-executive Director of Roche AG since 2001. He has been a founding Director of three biotechnology start-up companies, a member of MRC-UK Council and a Council Member of the Academy of Medical Sciences. He is a Board Member of the UK Clinical Research Collaboration and chairs the Science Committee of UK Biobank and the Oxford Health Alliance as well as other Oxford-based research boards.

Dr. Elizabeth Barrett-Connor
Professor and Division Chief of Epidemiology
Department of Family and Preventive Medicine
University of California, San Diego School of Medicine, La Jolla, USA

Dr. Elizabeth Barrett-Connor's research addresses healthy aging with a particular focus on gender differences and women's health. As a professor, principal investigator in several multi-centre clinical trials, and the author of more than 600 publications, Dr. Barrett-Connor's pioneering work has involved cardiovascular disease, diabetes, cancer, osteoporosis, memory loss and hormones. She is also the founder and Director of the Rancho Bernardo Heart and Chronic Disease Study, begun in 1972 and continuously supported by the NIH.

A Master of the American College of Physicians of Medicine and a member of the Institute of Medicine, Dr. Barrett-Connor has received numerous awards and served as President of the Epidemiology Section of the American Public Health Association; President of the Epidemiology Council of the American Heart Association; President of the Society for Epidemiologic Research; President of the American Epidemiological Society; Member of the Armed Forces Epidemiology Board, and a member of the Advisory Council of the National Institute on Aging.

Lisa Berkman, PhD
Professor, Harvard School of Public Health
Department of Society, Human Development and Health, Boston, USA

Lisa Berkman is the Thomas D. Cabot Professor in Public Policy, a professorship established to address health-related public policy issues at the Harvard School of Public Health. She is chair of the Department of Society, Human Development and Health and chair of the Harvard Center for Society and Health. Dr. Berkman is an internationally recognized social epidemiologist whose work focuses extensively on psychosocial influences on health outcomes. She edited Social Epidemiology, the first systematic account of the field of social determinants of health.

Dr. Berkman's primary studies are large prospective longitudinal cohort studies, such as the Established Populations for the Epidemiologic Study of the Elderly studies (EPESE) and the MacArthur Foundation Research Network on Successful Aging. She is past president of the Society for Epidemiologic Research and a member of the Institute of Medicine.

Barry R. Bloom
Dean of the Harvard School of Public Health
Joan L. and Julius H. Jacobson, II, Professor of Public Health
Harvard University, Boston, USA

Barry R. Bloom is widely recognized for his scientific work in infectious diseases, vaccines and international health. With an AB from Amherst College and a PhD from Rockefeller University, he became a White House consultant on International Health Policy and an Investigator at the Howard Hughes Medical Institute. Bloom was also President of the American Association of Immunologists (1984) and President of the Federation of American Societies for Experimental Biology (1985). He has served on several national NIH committees, on the US National Vaccine Advisory Committee, and on the Scientific Advisory Board of the National Center for Infectious Diseases at the Center for Disease Control. His awards include the first Bristol-Myers Squibb Award for Distinguished Research in Infectious Diseases, the John Enders Award of the Infectious Diseases Society of America (1994), and a share of the Novartis Award in Immunology (1998).

Bloom is currently a member of the WHO Global Advisory Committee on Health Research, a member of the National Academy of Sciences, the Institute of Medicine, the American Philosophical Society, the Ellison Medical Foundation Scientific Advisory Board, and the Scientific Advisory Board of the Wellcome Trust Center for Human Genetics in Oxford, UK, among others.

Gérard Bréart
Director, Epidemiology of Maternal and Child Health
INSERM Unité 149, Maternité - Hôpital Tenon, Paris, France

Since joining the Institut national de la santé et de la recherche médicale as a researcher in 1976, Dr. Bréart has combined his interest in epidemiology and statistics with a commitment to reducing maternal and neonatal mortality and morbidity. Over the years, he has held numerous posts in INSERM including Research Director and member of Governing Council. Presently the Director of a research unit in epidemiology in perinatal and women's health at the Hôpital Tenon, Bréart is also an Adjunct Professor in the Department of Maternal and Child Health at the School of Public Health at the University of North Carolina, Chapel Hill.

Bréart has been an educator, research administrator and member of the French National Committee on Ethics. He is also the past President of the Association of French-speaking Epidemiologists and the French Society of Perinatal Medicine. Dr. Bréart has authored and co-authored over 260 indexed publications.

Mrs. Lynda S. Cranston
President and CEO, Provincial Health Services Authority, Vancouver, Canada

Since 2002, the former first CEO of the Canadian Blood Services has served as President and CEO of British Columbia's Provincial Health Services Authority (PHSA). This agency plans and delivers highly specialized provincial health services through the BC Cancer Agency, BC Centre for Disease Control, BC Drug and Poison Information Centre, BC Provincial Renal Agency, BC Transplant Society, Forensic Psychiatric Services Commission, and several hospitals involved with women's and children's health.

A recipient of numerous awards, including being named one of Canada's Most Powerful Women in 2004 and 2005, Mrs. Cranston is on the board of the Canadian Healthcare Association, Comprehensive Care International, and is President of the Association of Canadian Academic Healthcare Organizations. She is past Chair of the Board of the Health Employers Association of BC, and was a member of the Premier's Advisory Council on Health in Alberta.

Ms. Karen Davis
President, The Commonwealth Fund, New York City, USA

Karen Davis is president of The Commonwealth Fund, a national philanthropy engaged in independent research on health and social policy issues. Ms. Davis assumed the presidency of the fourth-oldest private foundation in the country on January 1, 1995. Established by Anna M. Harkness in 1918 with the broad charge to enhance the common good, the Fund seeks ways to help Americans live healthy and productive lives, giving special attention to those groups with serious and neglected problems. She is a nationally recognized economist, with a distinguished career in public policy and research. Before joining the Fund, she served as chairman of the Department of Health Policy and Management at The Johns Hopkins School of Public Health, where she also held an appointment as professor of economics. She served as deputy assistant secretary for health policy in the Department of Health and Human Services from 1977-1980, and was the first woman to head a US Public Health Service agency.

Dr. Jeffrey M. Drazen
Editor-in-Chief, New England Journal of Medicine, Boston, USA

Dr. Drazen was born in Missouri, attended Tufts University and Harvard Medical School, and served his medical residency at Peter Bent Brigham Hospital. He has served as Chief of Pulmonary Medicine at Beth Israel Hospital, Chief of the Combined Pulmonary Divisions of Beth Israel and Brigham and Women's Hospitals, and Chief of Pulmonary Medicine at Brigham and Women's Hospital. His research has defined the role of novel endogenous chemical agents in asthma, leading to four new licensed pharmaceuticals. In 2000, he became Editor-in-Chief of the New England Journal of Medicine. During his tenure, the Journal has published major papers advancing the science of medicine, including the first descriptions of SARS and papers modifying the treatment of cancer, heart disease and lung disease.

Professeur Jacques Glowinski
Titulaire de la chaire de neuropharmacologie
Collège de France, Paris, France

Internationally recognized as one of the founders of neuropharmacology in France, Professor Jacques Glowinski has spent nearly forty years working in the field of neurotransmission and particularly on central monoaminergic systems. His investigations on dopaminergic systems had a great clinical impact on Parkinson's disease and has also consolidated the dopamine hypothesis of schizophrenia. Trained at the Pasteur Institute and then at the NIH (USA) with the Nobel prize winner J. Axelrod, J. Glowinski is the Director of an INSERM unit (Institut national de la santé et de la recherche médicale), in which numerous young scientists received their training. J. Glowinski was a Research Director of INSERM and is now Professor at the Collège de France (Neuropharmacology chair) as well as President of this Institution. He is also a member of the French Academy of Science. He has received several international scientific honours and awards including the Loundsberry Prize and more recently the prestigious prize of Medical research and the INSERM Prix d'honneur. He received an honorary Doctorate PhD from the Université de Montréal in 2003.

Steven R. Goldring, MD
Professor of Medicine, Harvard Medical School
Chief of Rheumatology, New England Baptist Hospital and Beth Israel Deaconess Medical Center, Boston, USA

A graduate of Washington University School of Medicine, St. Louis, Missouri, Steven Goldring completed his residency at Peter Bent Brigham Hospital and his rheumatology training at the Massachusetts General Hospital in Boston.

His research focuses on bone and cartilage biology, osteoporosis and cytokines and the role of inflammatory mediators in bone and cartilage loss in rheumatoid arthritis and other inflammatory disorders.

Currently the Director of Research of the New England Baptist Bone and Joint Institute Laboratory at Harvard, Goldring is the past Secretary-Treasurer of the American Society of Bone and Mineral Research and has served on the executives of several NIH committees and conferences related to bone biology and arthritis.

Dr. Goldring has received several national awards for his work in arthritis and rheumatology as well as Paget's Disease. He is a member of the American College of Rheumatology, the American Society of Bone and Mineral Research, International Bone and Mineral Society and the Orthopaedic Research Society. Goldring is an Associate Editor of Arthritis Research and a member of the editorial boards of Bone and the Journal of Bone and Mineral Research.

Dr. Lawrence W. Green
Adjunct Professor, Department of Epidemiology and Biostatistics
University of California, San Francisco, San Francisco, USA

Prof. Lawrence W. Green leads the Social and Behavioral Sciences Program at the University of California at San Francisco Comprehensive Cancer Center. He recently retired from the Center for Disease Control as Distinguished Fellow/Visiting Scientist and Director of the Office of Science and Extramural Research. He has served on the medical and public health faculties at Berkeley, Johns Hopkins, Harvard, Texas, UBC, and Emory Universities. He is a past President and Distinguished Fellow of the Society for Public Health Education, recipient of the American Public Health Association's highest awards, the Distinguished Career Award and Award of Excellence, and the American Academy of Health Behavior Research Laureate Medal.

Dr. Thomas Greenfield
Alcohol Research Group, National Alcohol Research Center
Public Health Institute, Berkeley, USA

Thomas Greenfield directs the National Alcohol Research Center, is the Senior Scientist and Executive Director of the Alcohol Research Group (ARG) and is an Adjunct Assistant Professor in the Department of Psychiatry at the University of California at San Francisco. His interest in epidemiology of alcohol use, treatment and prevention, measurement methodology and policy studies have involved him as a Principal Investigator in projects related to alcohol consumption, the mandate of alcohol warning labels and a study of ethnic and social influences on alcohol mortality.

After earning a PhD in clinical psychology at The University of Michigan, Dr. Greenfield spent eight years as a researcher at Washington State University and then became Associate Director for Research at the Marin Institute for the Prevention of Alcohol and Other Drug Problems. At ARG he is also responsible for National Alcohol Surveys, held every five years. He is an Assistant Editor of the journal Addiction and former Vice President and current Secretary of the Kettil Bruun Society for Social and Epidemiological Research on Alcohol.

Dr. Jack Guralnik
Chief, Epidemiology and Demography Section
National Institute on Aging, Bethesda, USA

Dr. Jack Guralnik is Chief of the Intramural Laboratory of Epidemiology, Demography and Biometry at the National Institute on Aging. He obtained his M.P.H. degree from the University of California, Berkeley, in 1982 and his PhD in epidemiology in 1985. He is Board Certified in Public Health and General Preventive Medicine. He has been in the intramural epidemiology research program at the National Institute on Aging since 1985. His primary areas of interest in the epidemiology of aging include the study of physical functioning and disability, the prevalence and impact of multiple co-existing chronic conditions, factors associated with healthy aging, methods of assessment of health and functional status, and trends in demographic and health status characteristics of the older population. He has published over 325 journal articles and book chapters in these areas of aging research and has taught and lectured extensively in the US and abroad.

Professor D'Arcy Holman
Centre for Health Services Research, School of Population Health
The University of Western Australia, Nedlands, Australia

Professor D'Arcy Holman holds the Foundation Chair in Public Health at The University of Western Australia School of Population Health. He is known for his strategic contributions to health services research, as an expert adviser to governments and community organizations. He leads the WA Data Linkage Project. He has published over 370 works and attracted over Aus$30 million in grants. His research interests focus on the utilisation and outcomes of health care, particularly using applications of data linkage and spatial analysis. In 2003, he was awarded the Centenary Medal of Australia for his services to the health system.

Dr. Edward R. B. McCabe
Department of Pediatrics. David Geffen School of Medicine
University of California, Los Angeles, Los Angeles, USA

Edward R.B. McCabe, MD, PhD, is Professor of Pediatrics and Human Genetics, David Geffen School of Medicine at UCLA, and Physician-in-Chief of the Mattel Children's Hospital at UCLA. He serves as Co-Director of the UCLA Center for Society and Genetics, an interdisciplinary group committed to exploring the interface between and co-evolution of culture and science. A pediatrician and geneticist involved in basic research and policy development, Dr. McCabe was elected to the Institute of Medicine in 2001. He was a Member of the Human Cloning Panel of the National Academy of Sciences (2001-2002), and Chair of the US Health and Human Services Secretary's Advisory Committees on Genetic Testing (1998-2002) and Genetics, Health and Society (2002-2004).

Eric M. Meslin, PhD
Director, Indiana University Center for Bioethics, Indianapolis, USA

Eric Meslin is Director of the Indiana University Center for Bioethics, Assistant Dean for Bioethics, Professor of Medicine, and Professor of Medical and Molecular Genetics in the Indiana University School of Medicine. He is also Professor of Philosophy in the School of Liberal Arts. From 1998-2001, he was Executive Director of the US National Bioethics Advisory Commission (NBAC), which was established by President Bill Clinton to advise the White House and the federal government on a range of bioethics issues including cloning, stem cell research, international clinical trials, and genetics studies. Eric has a PhD from the Bioethics Program in Philosophy at the Kennedy Institute of Ethics, Georgetown University in Washington, D.C., holds academic positions at the University of Toronto and at the University of Oxford and has authored more than 80 publications.

Pamela Mitchell, PhD, CNRN, FAAN
Associate Dean for Research, School of Nursing, University of Washington
Seattle, USA

An Elizabeth S. Soule Professor at the University of Washington, Dr. Mitchell teaches management of clinical effectiveness and functional approaches to clinical neuroscience. She is also an Adjunct Professor, Department of Health Services, SPHCM and Director, Center for Health Sciences Interprofessional Education Biobehavioral Nursing and Health Systems.

Her research for the past twenty years has involved investigation of fundamental physiologic factors influencing the responses of critically ill neurologic / neurosurgical patients to ordinary nursing care activities with an eye to enhancing their recovery. Other research focuses on how the organization and delivery of critical care influence patient outcomes, with particular emphasis on the impact of interprofessional education and practice.

Dr. Mitchell chairs the Initial Review Group, National Institute of Nursing Research, serves on the Advisory Council to Triservice Nursing Research, and serves on the Steering Committee for the Agency for Health Care Research and Quality Patient Safety Initiatives.

Arnold Munnich
Head of Genetic Services, Hôpital Necker-Enfants Malades, Paris, France

Biochemist, paediatrician and geneticist, Dr. Arnold Munnich's research and prenatal counseling have helped hundreds of French families affected by genetic illnesses. He and his team have isolated and identified approximately 30 genes responsible for a variety of genetic diseases affecting children.

Munnich received his doctorate in genetics in 1988 and has taught genetics at the University of Paris since 1989. Since 1994, he has been the Director of the Children's Genetic Disease Unit at the Hôpital Necker-Enfants Malades and Director of l'Unité de recherches sur les handicaps génétiques de l'enfant, INSERM, U-393.

A former Senior Researcher at the Institut national de la santé et de la recherche médicale (INSERM) and member of the INSERM Scientific Commission no. 1 (CSS 1) from 1987-1991, Munnich received the prestigious Grand Prix INSERM in 2000 among other awards. He has published extensively, serves on the editorial boards of numerous genetics journals and is a member of the French Académie des sciences, the Board of the United Mitochondrial Disease Foundation and other international organizations.

Dr. Eric N. Olson
Professor and Chairman, Department of Molecular Biology, University of Texas
Dallas, USA

Dr. Eric Olson received a B.A. from Wake Forest University, Winston-Salem, N.C., and a PhD from Bowman Gray School of Medicine of Wake Forest University. After a postdoctoral fellowship at Washington University School of Medicine, he joined the Department of Biochemistry and Molecular Biology at The University of Texas M. D. Anderson Cancer Center as an Assistant Professor where he rose to the rank of Professor and Chairman. In 1995, he moved to The University of Texas Southwestern Medical Center at Dallas, where he is professor and chairman of the Department of Molecular Biology. He holds the Annie and Willie Nelson Professor in Stem Cell Biology Chair. Dr. Olson is a member of the American Academy of Arts and Sciences, the National Academy of Sciences, and the Institute of Medicine. He has been active on many scientific advisory boards and serves on the editorial boards of numerous scientific journals.

Dr. Roger Perlmutter
Executive Vice President - Research and Development, Amgen Incorporated
Thousand Oaks, USA

Dr. Perlmutter is Executive Vice President for Research and Development at Amgen, Inc., the world's largest biotechnology company. Dr. Perlmutter is also a Director of Stem Cells, Inc., a Trustee of Reed College, and Chairman of the Board of Directors of the Institute for Systems Biology, a not-for-profit research Institute based in Seattle, Washington. Prior to joining Amgen in 2001, he was Executive Vice President at Merck and Co. Dr. Perlmutter received his MD and PhD degrees from Washington University (St. Louis) in 1979. Thereafter he pursued clinical training in internal medicine at the Massachusetts General Hospital and at the University of California at San Francisco. In the 1980's, at the California Institute of Technology and at the Howard Hughes Medical Institute at the University of Washington (Seattle) he focused his scientific efforts on the elucidation of signaling pathways governing lymphocyte development and activation.

Bruce Ponder FRCP, FRCPath, FMedSci, FRS
Cancer Research UK Department of Oncology
University of Cambridge, Cambridge, UK

Bruce Ponder is Professor of Oncology at the University of Cambridge and Director-designate of the new Cancer Research UK Cambridge Research Institute, which opens in 2006. He is also co-Director of the MRC/Hutchison Cancer Research Centre and of the Strangeways Laboratories for Genetic Epidemiology, also in Cambridge. He trained in internal medicine and medical oncology, and did his PhD on nucleosome positioning in polyoma alongside Tony Pawson at the Imperial Cancer Research Fund. His research interests have been in developmental biology - clonal organization in mouse chimeras - and in laboratory and clinical aspects of cancer genetics. He was elected FRS for contributions in these fields, in 2001.

Dr. Clifton A. Poodry
Director of Minority Opportunities in Research Division
National Institutes of Health, Bethesda, USA

As Director of the Minority Opportunities in Research (MORE) Division at the National Institute for General Medical Sciences (NIGMS), Dr. Poodry develops and implements policies and plans for minority research and research training programs and liaises with NIH, other federal agencies and the scientific community. A native of Tonawanda Seneca Indian Reservation in Western New York, Dr. Poodry earned an MA in Biology at the State University of New York at Buffalo, and a PhD from Case Western Reserve University. A Professor of Biology at the University of California, Santa Cruz, until 1994, Dr. Poodry also served in several administrative capacities. In 1995, he received the Ely S. Parker Award from the American Indian Science and Engineering Society for contributions in science and service to the American Indian community, and in 1999 he was awarded an Honorary Doctorate from The State University of New York in recognition of his scientific accomplishments and his activities on behalf of minority students.

Dr. Elio Riboli
Professor and Chair, Cancer Epidemiology and Prevention
Department of Epidemiology & Public Health, Faculty of Medicine
Imperial College London, London, UK

Elio Riboli has an MD degree (1977, Milan), a Master of Public Health (1980, Milan) and a Master of Science in Epidemiology (1982, Harvard, Boston, USA). Between 1978 and 1983, he worked at the National Institute for Research on Cancer in Milan. In 1983, he moved to IARC-WHO in Lyon. In 1989, he initiated the European Prospective Investigation into Cancer and Nutrition (EPIC), which eventually included 26 centres in 10 European countries. Over the past decade, he has coordinated research projects based on EPIC into the role of nutrition, lifestyle, environment, genetics and metabolic and hormonal factors in the etiology of cancer and chronic disease. In November 2005, he took up the post of Professor and Chair in Cancer Epidemiology and Prevention at Imperial College London.

Professor Fiona Stanley, AC
Director, Telethon Institute for Child Health Research
Executive Director, Australian Research Alliance for Children and Youth
Professor, School of Paediatrics and Child Health
University of Western Australia, Perth, Australia

Professor Stanley is the Founding Director of the Telethon Institute for Child Health Research; Executive Director of the Australian Research Alliance for Children and Youth; and Professor, School of Paediatrics and Child Health at the University of Western Australia. Trained in maternal and child health epidemiology and public health, Professor Stanley has spent her career researching the causes of major childhood illnesses and birth defects. For her research on behalf of Australia's children, she was named Australian of the Year in 2003. Her research includes the gathering and analysis of population data for epidemiological and public health research; the causes and prevention of birth defects and major neurological disorders, particularly the cerebral palsies and spina bifida; patterns of maternal and child health in Aboriginal and Caucasian populations; various ways of determining the developmental origins of health and disease; collaborations to link research, policy and practice; and strategies to enhance health and well-being in populations.

Dr. Barbara Starfield
Professor, Health Policy and Management
Johns Hopkins University School of Public Health, Baltimore, USA

Dr. Starfield is University Distinguished Professor of Health Policy at the Johns Hopkins University. Her work focuses on understanding the impact of health services on health, especially with regard to the relative contributions of primary care and specialty care, using both clinical and population-based approaches. Main areas of interest are in primary care, equity in health, health status assessment of children and youth, and case-mix assessment and quality of care. She was the founding and first president of the International Society for Equity in Health.

Dr. Ralph M. Steinman
Henry G. Kunkel Professor & Senior Physician
The Rockefeller University, Laboratory of Physiology and Immunology
New York City, USA

Ralph M. Steinman, MD, is Henry G. Kunkel Professor at The Rockefeller University and a senior physician at The Rockefeller University Hospital. He heads the Laboratory of Cellular Physiology and Immunology. In addition to research in fundamental mechanisms of immunity and tolerance, Steinman studies the interface of the immune system with several disease states, including research aimed at developing vaccines and immune-based therapies for tumors, infections and autoimmune diseases. Dr. Steinman is an editor of the Journal of Experimental Medicine. He is a member of the US National Academy of Sciences and its Institute of Medicine.

Professor Alan Walker
Department of Sociological Studies, University of Sheffield, Sheffield, UK

Alan Walker is Professor of Social Policy and Social Gerontology at the University of Sheffield, UK. A specialist in social gerontology and social policy, he has been researching and writing on aspects of ageing and social policy, including employment, for over 30 years. He is currently Director of a major multidisciplinary research program in the UK and of the European Research Area in Ageing, a project to develop a European strategy on ageing. Previously, he directed the UK Growing Older Programme, dedicated to promoting research to improve the quality of life in old age, and the European Forum on Population Ageing which, in 2005, developed into the ERA-Aging project. He also chaired the European Observatory on Ageing and Older People. He has published more than 20 books and 300 scientific papers. Recent books include Growing Older - Extending Quality Life (2004), Growing Older in Europe (2004) and Understanding Quality of Life in Old Age (2005) all published by McGraw-Hill.